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FADS1

  • Official Full Name

    fatty acid desaturase 1

  • Overview

    The protein encoded by this gene is a member of the fatty acid desaturase (FADS) gene family. Desaturase enzymes regulate unsaturation of fatty acids through the introduction of double bonds between defined carbons of the fatty acyl chain. FADS family members are considered fusion products composed of an N-terminal cytochrome b5-like domain and a C-terminal multiple membrane-spanning desaturase portion, both of which are characterized by conserved histidine motifs. This gene is clustered with family members FADS1 and FADS2 at 11q12-q13.1; this cluster is thought to have arisen evolutionarily from gene duplication based on its similar exon/intron organization.
  • Synonyms

    FADS1; fatty acid desaturase 1; LLCDL1; D5D; delta 5 desaturase; FADS6; FADSD5; TU12; delta-5 desaturase; delta(5) desaturase; delta-5 fatty acid desaturase; delta(5) fatty acid desaturase; linoleoyl-CoA desaturase (delta-6-desaturase)-like 1; FLJ38956; F;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Homo sapiens (Human)
  • Human
  • Mouse
  • Mus musculus (Mouse)
  • Papio anubis (Olive baboon)
  • Rat
  • Rattus norvegicus (Rat)
  • E. coli
  • E.coli
  • E.coli expression system
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human FADS1-12639H Recombinant Human FADS1, GST-tagged E.coli GST 173-444a.a.
Human FADS1-28816TH Recombinant Human FADS1 Wheat Germ N/A 99 amino acids
Human FADS1-781H Recombinant Human FADS1 Mammalian Cell His
Human FADS1-28817H Recombinant Human FADS1 protein, GST-tagged Wheat Germ GST 1 a.a. - 444 a.a.
Human FADS1-6472HCL Recombinant Human FADS1 293 Cell Lysate HEK293 N/A
Human FADS1-17H Recombinant Human FADS1 Protein, His-tagged E.coli His 2-121
Human FADS1-2895H Recombinant Human FADS1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human FADS1-023H Recombinant Human FADS1 Protein, His-tagged E. coli His 2-121
Human FADS1-622HF Recombinant Full Length Human FADS1 Protein, GST-tagged In Vitro Cell Free System GST 444 amino acids
Human FADS1-2895H-B Recombinant Human FADS1 Protein Pre-coupled Magnetic Beads HEK293
Mouse FADS1-5431M Recombinant Mouse FADS1 Protein Mammalian Cell His
Mouse FADS1-2933M-B Recombinant Mouse FADS1 Protein Pre-coupled Magnetic Beads HEK293
Mouse FADS1-2933M Recombinant Mouse FADS1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat FADS1-2192R Recombinant Rat FADS1 Protein Mammalian Cell His
Rat FADS1-1849R-B Recombinant Rat FADS1 Protein Pre-coupled Magnetic Beads HEK293
Rat FADS1-1849R Recombinant Rat FADS1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Homo sapiens (Human) RFL8336HF Recombinant Full Length Human Fatty Acid Desaturase 1(Fads1) Protein, His-Tagged E.coli expression system His Full Length (1-501)
Mus musculus (Mouse) RFL35517MF Recombinant Full Length Mouse Fatty Acid Desaturase 1(Fads1) Protein, His-Tagged E.coli expression system His Full Length (1-447)
Papio anubis (Olive baboon) RFL4442PF Recombinant Full Length Papio Anubis Fatty Acid Desaturase 1(Fads1) Protein, His-Tagged E.coli expression system His Full Length (1-444)
Rattus norvegicus (Rat) RFL13823RF Recombinant Full Length Rat Fatty Acid Desaturase 1(Fads1) Protein, His-Tagged E.coli expression system His Full Length (1-447)
  • Involved Pathway
  • Protein Function
  • Interacting Protein

FADS1 involved in several pathways and played different roles in them. We selected most pathways FADS1 participated on our site, such as Biosynthesis of unsaturated fatty acids, Fatty acid metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with FADS1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Biosynthesis of unsaturated fatty acidsACOT1;TECR;BAAT;ACOX3;HSD17B12B;ELOVL5;ACOT7;ELOVL2;HADHA
Fatty acid metabolismACADM;CPT2;HADHAB;ELOVL5;CPT1A;HSD17B12B;MCAT;SCDB;ACOX3

FADS1 has several biochemical functions, for example, C-5 sterol desaturase activity, oxidoreductase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by FADS1 itself. We selected most functions FADS1 had, and list some proteins which have the same functions with FADS1. You can find most of the proteins on our site.

Function Related Protein
C-5 sterol desaturase activitySC5DL;FADS1
oxidoreductase activityETFDH;FDFT1;RNLS;ERO1L;CYP2AD3;CYP26C1;CYP19A1B;PYCR1B;AKR1E1

FADS1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FADS1 here. Most of them are supplied by our site. Hope this information will be useful for your research of FADS1.

q65zq1_human; PAAF1; DHCR7; CCDC22

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