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FCRL1

Official Full Name

Fc receptor-like 1
Overview

This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein contains three extracellular C2-like immunoglobulin domains, a transmembrane domain and a cytoplasmic domain with two immunoreceptor-tyrosine activation motifs. This protein may play a role in the regulation of cancer cell growth. Alternative splicing results in multiple transcript variants.
Synonyms

FCRL1; Fc receptor-like 1; Fc receptor-like protein 1; CD307a; FCRH1; IFGP1; IRTA5; RP11 367J7.7; Fc receptor homolog 1; Fc receptor like protein 1; FcR like protein 1; FCRH 1; FCRL 1; hIFGP 1; hIFGP1; IFGP 1; IFGP family protein 1; Immune receptor translocation associated protein 5; immunoglobulin superfamily Fc receptor, gp42; IRTA 5; fcR-like protein 1; immune receptor translocation-associated protein 5;

Type

Recombinant Proteins
Cell & Tissue Lysates

Species

Human
Mouse
Rhesus monkey

Source

E.coli
HEK293
Human Cell
In Vitro Cell Free System
Mammalian cells
Wheat Germ

Tag

Fc
GST
hIgG4
His
Non

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	FCRL1-4005H	Recombinant Human FCRL1 Protein	Wheat Germ	Non		Inquiry
Human	FCRL1-027H	Recombinant Human FCRL1 protein, Gst-His-tagged	E.coli	His&GST		Inquiry
Human	FCRL1-4006H	Recombinant Human FCRL1 Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	FCRL1-3211H	Recombinant Human FCRL1 protein, His-tagged	HEK293	His	Met1-Asn303	$623 / 50 µg
Human	FCRL1-2227HCL	Recombinant Human FCRL1 cell lysate	Human Cell	Non		Inquiry
Human	FCRL1-3990H	Recombinant Human FCRL1 Protein (Met1-Ser307), C-His tagged	Mammalian cells	His	Met1-Ser307	Inquiry
Human	FCRL1-4767HF	Recombinant Full Length Human FCRL1 Protein	In Vitro Cell Free System		458 amino acids	Inquiry
Human	FCRL1-2803H	Recombinant Human FCRL1 Protein (Ala17-Asn303), C-His tagged	Mammalian cells	His	Ala17-Asn303	Inquiry
Human	FCRL1-4768HF	Recombinant Full Length Human FCRL1 Protein, GST-tagged	In Vitro Cell Free System	GST	429 amino acids	Inquiry
Mouse	Fcrl1-8689M	Recombinant Mouse FCRL1 protein(Met1-Thr204), His-tagged	HEK293	His	Met1-Thr204	Inquiry
Mouse	FCRL1-1379MCL	Recombinant Mouse FCRL1 cell lysate	Human Cell	Non		Inquiry
Mouse	Fcrl1-5760M	Recombinant Mouse Fcrl1 Protein (Ala17-Ser219), C-His tagged	Mammalian cells	His	Ala17-Ser219	Inquiry
Rhesus monkey	FCRL1-1709R	Recombinant Rhesus Monkey FCRL1 Protein	HEK293	Non	17-300	Inquiry
Rhesus monkey	FCRL1-1710R	Recombinant Rhesus Monkey FCRL1 Protein, hIgG1-tagged	HEK293	Fc	17-300	Inquiry
Rhesus monkey	FCRL1-1711R	Recombinant Rhesus Monkey FCRL1 Protein, hIgG4-tagged	HEK293	hIgG4	17-300	Inquiry

Other Resource

FCRL1 involved in several pathways and played different roles in them. We selected most pathways FCRL1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with FCRL1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

FCRL1 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by FCRL1 itself. We selected most functions FCRL1 had, and list some proteins which have the same functions with FCRL1. You can find most of the proteins on our site.

Function	Related Protein

FCRL1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FCRL1 here. Most of them are supplied by our site. Hope this information will be useful for your research of FCRL1.

Research Area

B Cell Receptor-Associated Proteins

Fc Receptors

ITIM/ITAM Immunoreceptors and Related Molecules

Shabani, M; Bayat, AA; et al. Ligation of human Fc receptor like-2 by monoclonal antibodies down-regulates B-cell receptor-mediated signalling. IMMUNOLOGY 143:341-353(2014).

Shabani, M; Hemmati, A; et al. Cloning, Expression and Characterization of Recombinant Human Fc Receptor Like 1, 2 and 4 Molecules. IRANIAN JOURNAL OF BIOTECHNOLOGY 11:182-192(2013).