FGF6

  • Official Full Name

    fibroblast growth factor 6

  • Overview

    The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene displayed oncogenic transforming activity when transfected into mammalian cells. The mouse homolog of this gene exhibits a restricted expression profile predominantly in the myogenic lineage, which suggested a role in muscle regeneration or differentiation.
  • Synonyms

    FGF6; fibroblast growth factor 6; FGF-6; HST-2; HSTF-2; OTTHUMP00000238378; heparin-binding growth factor 6; heparin secretory-transforming protein 2; HST2; HBGF-6;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • E.coli
  • HEK293
  • Mammalian Cell
  • C
  • His
  • GST
  • His (Fc)
  • Avi
  • His|GST
  • His|T7
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human FGF6-176H Recombinant Human Fibroblast Growth Factor 6 E.coli N/A
Human FGF6-12872H Recombinant Human FGF6, GST-tagged E.coli GST 38-208a.a.
Human FGF6-644H Recombinant Human FGF6 protein, His & GST-tagged E.coli His/GST Gly41~Ile208 (Accession # P10767)
Human FGF6-573H Recombinant Human FGF6 E.coli N/A
Human FGF6-6237HCL Recombinant Human FGF6 293 Cell Lysate HEK293 N/A
Human FGF6-89H Active Recombinant Human FGF6 Protein E.coli
Human FGF6-040H Active Recombinant Human FGF6 Protein E.coli
Human FGF6-412F Active Recombinant Human FGF6 Protein (169 aa) E.coli 169
Human FGF6-98H Active Recombinant Human FGF6 Protein (Gly41-Ile208), C-His tagged, Animal-free, Carrier-free E.coli C-His Gly41-Ile208
Mouse Fgf6-527M Active Recombinant Mouse Fibroblast Growth Factor 6 E.coli N/A
Mouse Fgf6-637M Active Recombinant Mouse Fgf6 E.coli N/A Pro39-Ile208
Mouse Fgf6-645M Recombinant Mouse Fgf6 protein, His & T7-tagged E.coli His/T7 Pro39~Ile208 (Accession # P21658)
Mouse FGF6-5855M Recombinant Mouse FGF6 Protein Mammalian Cell His
Mouse FGF6-3237M-B Recombinant Mouse FGF6 Protein Pre-coupled Magnetic Beads HEK293
Mouse FGF6-3237M Recombinant Mouse FGF6 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat Fgf6-646R Recombinant Rat Fgf6 protein, His & GST-tagged E.coli His/GST Ser38~Ile208
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource
  • FGF6 Related Signal Pathway

FGF6 involved in several pathways and played different roles in them. We selected most pathways FGF6 participated on our site, such as MAPK signaling pathway, Ras signaling pathway, Rap signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with FGF6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
MAPK signaling pathwayPPP3R1B;PPM1NB;GNA12A;FGF11A;TGFBR1;MAX;AKT2;PAK2A;CACNA1C
Ras signaling pathwayPIK3CB;FGF1;IGF1R;FGF7;ANGPT2;MAPK9;GNG11;GNB2;PIK3CG
Rap signaling pathwayKLK1B4;BCAR1;PFN1;RAP1GAP;NRAS;ITGB1;MAP2K2;GNAQ;IGF1
PIK-Akt signaling pathwayIFNA16;Fasl;LPAR3;FIGF;TNC;Pdgfa&Pdgfb;COL6A6;INS1;HSP90AB1
Regulation of actin cytoskeletonMYH10;GSNB;RAC1;ARHGEF7;PFN2;EZRB;MYL2B;ARHGEF7A;ABI2
Pathways in cancerCCDC6;KIT;BIRC5;XIAP;PDGFA;WNT1;GNGT2;AKT1;PRKCA
MelanomaIGF1;CDH1;PDGFRA;PDGFRB;MDM2;MITF;RB1;PDGFC;HGF

FGF6 has several biochemical functions, for example, fibroblast growth factor receptor binding, growth factor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by FGF6 itself. We selected most functions FGF6 had, and list some proteins which have the same functions with FGF6. You can find most of the proteins on our site.

Function Related Protein
fibroblast growth factor receptor bindingFGF1;FGF4;FGF18A;FGF16;FGF5;FGF20A;FGF8A;FGF8;Fgf15
growth factor activityIL6;RABEP2;FGF20;NRG3;LEFTY1;THPO;TGFB1;KLK1B3;VHL

FGF6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FGF6 here. Most of them are supplied by our site. Hope this information will be useful for your research of FGF6.

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