FGF6

  • Official Full Name

    fibroblast growth factor 6

  • Overview

    The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene displayed oncogenic transforming activity when transfected into mammalian cells. The mouse homolog of this gene exhibits a restricted expression profile predominantly in the myogenic lineage, which suggested a role in muscle regeneration or differentiation.

  • Synonyms

    FGF6;fibroblast growth factor 6;FGF-6;HST-2;HSTF-2;OTTHUMP00000238378;heparin-binding growth factor 6;heparin secretory-transforming protein 2;HST2;HBGF-6

Recombinant Proteins

  • Human
  • Mouse
  • Rat
  • E.coli
  • Mammalian Cells
  • HEK293
  • GST
  • Non
  • His
  • T7
  • Avi
  • Fc
Cat.# Product name Source (Host) Species Tag Protein Length Price
FGF6-12872H Recombinant Human FGF6, GST-tagged E.coli Human GST 38-208a.a.
Fgf6-527M Active Recombinant Mouse Fibroblast Growth Factor 6 E.coli Mouse Non 39-208 a.a.
Fgf6-637M Active Recombinant Mouse Fgf6 E.coli Mouse Non Pro39-Ile208
FGF6-176H Recombinant Human Fibroblast Growth Factor 6 E.coli Human Non
FGF6-573H Recombinant Human FGF6 E.coli Human Non 41-208 a.a.
FGF6-5855M Recombinant Mouse FGF6 Protein Mammalian Cells Mouse His
FGF6-644H Recombinant Human FGF6 protein, His & GST-tagged E.coli Human GST&His Gly41~Ile208
Fgf6-645M Recombinant Mouse Fgf6 protein, His & T7-tagged E.coli Mouse His&T7 Pro39~Ile208
Fgf6-646R Recombinant Rat Fgf6 protein, His & GST-tagged E.coli Rat GST&His Ser38~Ile208
FGF6-6237HCL Recombinant Human FGF6 293 Cell Lysate HEK293 Human Non
FGF6-040H Active Recombinant Human FGF6 Protein E.coli Human 41-208 a.a.
FGF6-3237M Recombinant Mouse FGF6 Protein, His (Fc)-Avi-tagged HEK293 Mouse Avi&Fc&His
FGF6-3237M-B Recombinant Mouse FGF6 Protein Pre-coupled Magnetic Beads HEK293 Mouse
FGF6-412F Active Recombinant Human FGF6 Protein (169 aa) E.coli Human 169
FGF6-89H Active Recombinant Human FGF6 Protein E.coli Human
FGF6-98H Active Recombinant Human FGF6 Protein (Gly41-Ile208), C-His tagged, Animal-free, Carrier-free E.coli Human His Gly41-Ile208

    Involved Pathway

    FGF6 involved in several pathways and played different roles in them. We selected most pathways FGF6 participated on our site, such as MAPK signaling pathway,Ras signaling pathway,Rap signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with FGF6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    PIK-Akt signaling pathway FGF12,INS1,GNB3,DDIT4,IFNAR1,FGF19,PRKAA2,HGF,Ifna15,TSC1
    MAPK signaling pathway NFKB2,TAB2,FGF13A,PRKCA,IL1R2,MAP3K13,RAC3B,DDIT3,STMN1,FGF1
    Ras signaling pathway PLA2G2A,Kitl,PDGFD,FGFR2,FGF2,RASA4,CALML5,ABL2,ZAP70,RASAL3
    Pathways in cancer TPM3,FN1,SKP2,WNT4,FGF18,GLI1,VEGFB,LAMB2,FGF7,PIK3R3
    Melanoma PDGFB,Pdgfa&Pdgfb,FGF9,NRAS,FGF10,FGF16,PDGFC,FGF3,FGF4,Fgf15
    Regulation of Actin Cytoskeleton ARPC5A,PDGFAB,PAK2A,FGF20,FGF10A,PIP5K1C,MYL1,ITGB2L,FGF8A,PPP1CB
    Rap signaling pathway TLN1,CALM4,SIPA1L1,PFN1,RAPGEF5,IGF1,FGF20,F2RL3,KITLG,ITGAL

    Protein Function

    FGF6 has several biochemical functions, for example, fibroblast growth factor receptor binding,growth factor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by FGF6 itself. We selected most functions FGF6 had, and list some proteins which have the same functions with FGF6. You can find most of the proteins on our site.

    Function Related Protein
    growth factor activity TIMP1,HBEGFA,HDGF,EREG,WISP3,IL8L2,CDNF,PTN,MACC1,FGF4
    fibroblast growth factor receptor binding FGF8,Fgf15,KLB,FGF20B,FGF8B,FGF16,FGF10,FGF10A,FGF8A,FGF1

    Interacting Protein

    FGF6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FGF6 here. Most of them are supplied by our site. Hope this information will be useful for your research of FGF6.

    FGF6 Related Signal Pathway

    Resources

    Gene Families

    Growth Factors

    Research Area

    FGF Family
    FGF Ligands
    Fibroblast Growth Factor (FGF)

    References

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