FGF6

Official Full Name

fibroblast growth factor 6
Background

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene displayed oncogenic transforming activity when transfected into mammalian cells. The mouse homolog of this gene exhibits a restricted expression profile predominantly in the myogenic lineage, which suggested a role in muscle regeneration or differentiation.
Synonyms

FGF6; fibroblast growth factor 6; FGF-6; HST-2; HSTF-2; OTTHUMP00000238378; heparin-binding growth factor 6; heparin secretory-transforming protein 2; HST2; HBGF-6;

Type:
Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species :
Human
Mouse
Rat

Source :
E. coli
E.coli
HEK293
Mammalian Cell

Tag :
C
His
GST
His (Fc)
Avi
His|GST
His|T7
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Price
Human	FGF6-176H	Recombinant Human Fibroblast Growth Factor 6	E.coli	N/A	Inquiry
Human	FGF6-12872H	Recombinant Human FGF6, GST-tagged	E.coli	GST	$319.00 / 25ug
Human	FGF6-644H	Recombinant Human FGF6 protein, His & GST-tagged	E.coli	His/GST	Inquiry
Human	FGF6-573H	Recombinant Human FGF6	E.coli	N/A	Inquiry
Human	FGF6-6237HCL	Recombinant Human FGF6 293 Cell Lysate	HEK293	N/A	Inquiry
Human	FGF6-89H	Active Recombinant Human FGF6 Protein	E.coli		Inquiry
Human	FGF6-040H	Active Recombinant Human FGF6 Protein	E. coli		Inquiry
Human	FGF6-412F	Active Recombinant Human FGF6 Protein (169 aa)	E.coli		Inquiry
Human	FGF6-98H	Active Recombinant Human FGF6 Protein (Gly41-Ile208), C-His tagged, Animal-free, Carrier-free	E.coli	C-His	Inquiry
Mouse	Fgf6-527M	Active Recombinant Mouse Fibroblast Growth Factor 6	E.coli	N/A	Inquiry
Mouse	Fgf6-637M	Active Recombinant Mouse Fgf6	E.coli	N/A	Inquiry
Mouse	Fgf6-645M	Recombinant Mouse Fgf6 protein, His & T7-tagged	E.coli	His/T7	Inquiry
Mouse	FGF6-5855M	Recombinant Mouse FGF6 Protein	Mammalian Cell	His	Inquiry
Mouse	FGF6-3237M-B	Recombinant Mouse FGF6 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry
Mouse	FGF6-3237M	Recombinant Mouse FGF6 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry
Rat	Fgf6-646R	Recombinant Rat Fgf6 protein, His & GST-tagged	E.coli	His/GST	Inquiry

Involved Pathway
Protein Function
Interacting Protein
FGF6 Related Research Area
FGF6 Related Signal Pathway

FGF6 involved in several pathways and played different roles in them. We selected most pathways FGF6 participated on our site, such as MAPK signaling pathway, Ras signaling pathway, Rap signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with FGF6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
MAPK signaling pathway	MKNK2;HSC70;CACNA1G;PRKACAB;MKNK2B;PAK2;FGF1;AKT2;RPS6KA3
Ras signaling pathway	CALML5;RAB5B;AKT1;NFKB1;PLA2G6;RASGRF2;RALGDS;GRIN1;PRKACB
Rap signaling pathway	CALM2;FGF9;PFN2;INS2;MAPK3;PRKD3;RAC1;MAP2K6;FGF22
PIK-Akt signaling pathway	ITGAV;ITGA3;CCND3;COL27A1;TNXB;FGF14;PPP2R5A;FGF6;MCL1
Regulation of actin cytoskeleton	ITGA2B;FN1A;PIK3CB;TMSB4Y;ACTN1;ITGA2;CYFIP2;BRAF;MAPK1
Pathways in cancer	VEGFC;RAC2;GNA11;FGFR3;BAX;Fzd4;PTGER4;RALBP1;AHA-1
Melanoma	Pdgfa&Pdgfb;NRAS;FGF4;CCND1;HGF;PIK3CD;PDGFRA;TP53;FGF12

FGF6 has several biochemical functions, for example, fibroblast growth factor receptor binding, growth factor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by FGF6 itself. We selected most functions FGF6 had, and list some proteins which have the same functions with FGF6. You can find most of the proteins on our site.

Function	Related Protein
fibroblast growth factor receptor binding	Fgf15;FGF8;FRS2;FGF8B;FRS3;FGF9;FGF6A;FGF10;FGF6B
growth factor activity	PDGFD;FGF16;IL5;NRG4;BMP4;GPI1;FBRS;Pdgfa&Pdgfb;NRG3

FGF6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FGF6 here. Most of them are supplied by our site. Hope this information will be useful for your research of FGF6.

FGF Family

FGF Ligands

Fibroblast Growth Factor (FGF)