FGF6
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Official Full Name
fibroblast growth factor 6
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Overview
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene displayed oncogenic transforming activity when transfected into mammalian cells. The mouse homolog of this gene exhibits a restricted expression profile predominantly in the myogenic lineage, which suggested a role in muscle regeneration or differentiation. -
Synonyms
FGF6; fibroblast growth factor 6; FGF-6; HST-2; HSTF-2; OTTHUMP00000238378; heparin-binding growth factor 6; heparin secretory-transforming protein 2; HST2; HBGF-6;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rat
- E.coli
- HEK293
- Mammalian Cell
- C
- His
- GST
- His (Fc)
- Avi
- His|GST
- His|T7
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
- Other Resource
- FGF6 Related Signal Pathway
FGF6 involved in several pathways and played different roles in them. We selected most pathways FGF6 participated on our site, such as MAPK signaling pathway, Ras signaling pathway, Rap signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with FGF6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| MAPK signaling pathway | Casp3;LRRK2;IL1B;HSPA1A;NR4A1;RAP1B;MEF2CB;GNG12A;PRKACA |
| Ras signaling pathway | RHOA;PLA1A;FGF8;INS2;PRKCG;KRAS;FGF19;PLA2G3;INS1 |
| Rap signaling pathway | RAPGEF5;THBS1;RAP1B;CALML5;GNAO1;PARD3;MAP2K1;PDGFB;MET |
| PIK-Akt signaling pathway | IFNA5;PHLPP2;IFNA13;IL2RG;TSC1;FLT4;TRP53;GRB2;IL7R |
| Regulation of actin cytoskeleton | DIAPH3;MYLPFA;RRAS2;PPP1CBL;PXN;ITGA2;MAPK1;TMSB;VAV3 |
| Pathways in cancer | PLD1;MAPK3;F2RL3;FZD9;MDM2;RUNX1;PTCH2;PTK2;TPR |
| Melanoma | FGF2;FGF11;CCND1;FGF17;FGF1;FGF22;FGF13;FGF5;IGF1R |
FGF6 has several biochemical functions, for example, fibroblast growth factor receptor binding, growth factor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by FGF6 itself. We selected most functions FGF6 had, and list some proteins which have the same functions with FGF6. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| fibroblast growth factor receptor binding | KLB;FGF2;FGF10B;FGF20A;FGF8B;FGF4;FGF6;FGF18A;FGF10A |
| growth factor activity | EFEMP1;IGF2B;FGF13;TGFB2;GDF2;FGF1B;GDF6;GDNF;TYMP |
FGF6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FGF6 here. Most of them are supplied by our site. Hope this information will be useful for your research of FGF6.
Research Area
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