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FGFR1OP

  • Official Full Name

    FGFR1 oncogene partner

  • Overview

    This gene encodes a largely hydrophilic protein postulated to be a leucine-rich protein family member. A t(6;8)(q27;p11) chromosomal translocation, fusing this gene and the fibroblast growth factor receptor 1 (FGFR1) gene, has been found in cases of myeloproliferative disorder. The resulting chimeric protein contains the N-terminal leucine-rich region of this encoded protein fused to the catalytic domain of FGFR1. This gene is thought to play an important role in normal proliferation and differentiation of the erythroid lineage. Alternatively spliced transcript variants that encode different proteins have been identified.
  • Synonyms

    FGFR1OP; FGFR1 oncogene partner; FOP; Fibroblast growth factor receptor 1 oncogene partner; OTTHUMP00000017612; OTTHUMP00000017613;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Cynomolgus Monkey
  • Human
  • Mouse
  • Zebrafish
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Insect Cell
  • Insect Cells
  • Mammalian Cell
  • Wheat Germ
  • Fc|His
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human FGFR1OP-496H Recombinant Human FGFR1OP, His-GST tagged Insect Cell Fc/His
Human FGFR1OP-6790H Recombinant Human FGFR1 Oncogene Partner, His-tagged E.coli His
Human FGFR1OP-12879H Recombinant Human FGFR1OP, GST-tagged E.coli GST 1-374a.a.
Human FGFR1OP-001HCL Recombinant Human FGFR1OP cell lysate Insect Cell N/A
Human FGFR1OP-4125H Recombinant Human FGFR1OP Protein, GST-tagged Wheat Germ GST
Human FGFR1OP-1320H Recombinant Human FGFR1OP protein(Ala2-Ala379), His&GST-tagged Insect Cells N-His&GST Ala2-Ala379
Human FGFR1OP-4887HF Recombinant Full Length Human FGFR1OP Protein, GST-tagged In Vitro Cell Free System GST 379 amino acids
Mouse FGFR1OP-5861M Recombinant Mouse FGFR1OP Protein Mammalian Cell His
Mouse FGFR1OP-3241M-B Recombinant Mouse FGFR1OP Protein Pre-coupled Magnetic Beads HEK293
Mouse FGFR1OP-3241M Recombinant Mouse FGFR1OP Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Cynomolgus Monkey FGFR1OP-524C Recombinant Cynomolgus FGFR1OP Protein, His-tagged Mammalian Cell His
Cynomolgus Monkey FGFR1OP-268C Recombinant Cynomolgus Monkey FGFR1OP Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Cynomolgus Monkey FGFR1OP-268C-B Recombinant Cynomolgus Monkey FGFR1OP Protein Pre-coupled Magnetic Beads HEK293
Zebrafish FGFR1OP-352Z Recombinant Zebrafish FGFR1OP Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • FGFR1OP Related Gene Family
  • FGFR1OP Related Research Area

FGFR1OP involved in several pathways and played different roles in them. We selected most pathways FGFR1OP participated on our site, such as Anchoring of the basal body to the plasma membrane, Assembly of the primary cilium, Cell Cycle, which may be useful for your reference. Also, other proteins which involved in the same pathway with FGFR1OP were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Anchoring of the basal body to the plasma membraneCCDC41;NDE1;DCTN3;NEK2;TCTN3;CEP89;TTBK2;DYNC1H1;RPGRIP1L
Assembly of the primary ciliumPLK4;TTC26;BBS13;CCT3;IFT20;EXOC8;IFT81;B9D1;DYNC1I2
Cell CycleMYBL2;GADD45B;YWHABL;SGOL1;CUL1A;SGOL2;PLK4;TERF2;SMC1AL
Cell Cycle, MitoticZWINT;CEP290;CEP78;NEK7;KNTC1;SMC2;MYCA;NCAPG2;CDKN2C
Centrosome maturationCETN2;OFD1;CEP70;NINL;TUBGCP2;HAUS2;ODF2;CSNK1D;NEDD1
DiseaseHDAC6;HMGA1;CDC37;EPM2A;CDK9;AP1G1;CCNC;EEF2;RDBP
Diseases of signal transductionCDC37;OPN1LW;HEY1;MIB1;JAG2;RBP4;STRA6;JAG1;TNKS
FGFR1 mutant receptor activationFGFR1OP;CUX1;MYO18A;TRIM24;LRRFIP1;CPSF6;FGFR1OP2

FGFR1OP has several biochemical functions, for example, protein binding, protein homodimerization activity, protein kinase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FGFR1OP itself. We selected most functions FGFR1OP had, and list some proteins which have the same functions with FGFR1OP. You can find most of the proteins on our site.

Function Related Protein
protein bindingFBXO46;IL1A;IGF2R;TSSC4;SIGLEC5;EYA4;LGALS8;MAK;B3GAT3
protein homodimerization activitySDCBP;DPY30;TENM1;HPGDS;GRPEL2;TCF3B;PRMT8;SQSTM1;CSF1
protein kinase bindingATF2;AURKA;LSM2;KCNA5;AXIN1;FGFR1OP;DCX;FZD5;TENC1
protein tyrosine kinase activityLCK;MAP2K6;PTK2AB;EPHA7;PTK2AA;IGF1R;KITA;CSF1RA;ERBB3A
protein tyrosine kinase inhibitor activityGNB2L1;FGFR1OP;IBTK

FGFR1OP has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FGFR1OP here. Most of them are supplied by our site. Hope this information will be useful for your research of FGFR1OP.

VASP; CEP19; PPP2CB; CTGF; CEP350; PACS1; NAGK; CEP350; CCHCR1; Lrrcc1; TBC1D31; PCM1; CSPP1; CCDC14

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