FGFR1OP

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FGFR1OP

Official Full Name FGFR1 oncogene partner
Background This gene encodes a largely hydrophilic protein postulated to be a leucine-rich protein family member. A t(6;8)(q27;p11) chromosomal translocation, fusing this gene and the fibroblast growth factor receptor 1 (FGFR1) gene, has been found in cases of myeloproliferative disorder. The resulting chimeric protein contains the N-terminal leucine-rich region of this encoded protein fused to the catalytic domain of FGFR1. This gene is thought to play an important role in normal proliferation and differentiation of the erythroid lineage. Alternatively spliced transcript variants that encode different proteins have been identified.
Synonyms FGFR1OP; FGFR1 oncogene partner; FOP; Fibroblast growth factor receptor 1 oncogene partner; OTTHUMP00000017612; OTTHUMP00000017613
    • Species :
    • Cynomolgus Monkey
    • Human
    • Mouse
    • Zebrafish
    • Source :
    • E.coli
    • Insect Cell
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • Fc
    • His
    • GST
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human FGFR1OP-001HCL Recombinant Human FGFR1OP cell lysate Insect Cell N/A
    Human FGFR1OP-12879H Recombinant Human FGFR1OP, GST-tagged E.coli GST
    Human FGFR1OP-4125H Recombinant Human FGFR1OP Protein, GST-tagged Wheat Germ GST
    Human FGFR1OP-496H Recombinant Human FGFR1OP, His-GST tagged Insect Cell Fc/His
    Human FGFR1OP-6790H Recombinant Human FGFR1 Oncogene Partner, His-tagged E.coli His
    Mouse FGFR1OP-5861M Recombinant Mouse FGFR1OP Protein Mammalian Cell His
    Cynomolgus Monkey FGFR1OP-524C Recombinant Cynomolgus FGFR1OP Protein, His-tagged Mammalian Cell His
    Zebrafish FGFR1OP-352Z Recombinant Zebrafish FGFR1OP Mammalian Cell His

    FGFR1OP involved in several pathways and played different roles in them. We selected most pathways FGFR1OP participated on our site, such as Anchoring of the basal body to the plasma membrane, Assembly of the primary cilium, Cell Cycle, which may be useful for your reference. Also, other proteins which involved in the same pathway with FGFR1OP were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Anchoring of the basal body to the plasma membrane CEP76; CEP89; RPGRIP1L; NEK2; CEP70; NPHP4; TMEM216; HAUS2; CEP290; CC2D2A
    Assembly of the primary cilium PROL1; UNC119B; ARF4; IFT-20; TTC21B; BBS1; FLR; CEP164; DYNC1I2; TNPO1
    Cell Cycle NEDD1; TTK; YWHAQB; CSNK2B; RNF168; SKP2; TERF2; NDEL1A; TUBGCP3; NUF2
    Cell Cycle, Mitotic CEP152; CDK11B; MYCA; CTDNEP1B; GMNN; STIL; MYBL2; NUF2; CDKN2D; PHF8
    Centrosome maturation ODF2B; CLASP1; PLK4; NDE1; CEP135; CETN2; CEP164; CEP70; DCTN1A; CP110
    Disease TRIM24; STRA6; TRAT1; CTBP2; AP1G1; PSIP1; CTDP1; TLR10; RPL35; NUP50
    Diseases of signal transduction TNKS2; RLBP1; KREMEN1; TRIM24; CPSF6; OPN1LW; JAG2; STRA6; OS9; CDC37
    FGFR1 mutant receptor activation CPSF6; MYO18A; LRRFIP1; CUX1; FGFR1OP; FGFR1OP2; TRIM24

    FGFR1OP has several biochemical functions, for example, protein binding, protein homodimerization activity, protein kinase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FGFR1OP itself. We selected most functions FGFR1OP had, and list some proteins which have the same functions with FGFR1OP. You can find most of the proteins on our site.

    Function Related Protein
    protein binding DZIP1L; THOC7; AMBRA1; SYT6; PIK3C2B; POSTN; RHOJ; SPEF2; TTPA; DERL3
    protein homodimerization activity PDGFA; STK25; CRYBB2; P2RX7; SUMF1; ERP29; ACAT1; GREM2; PON3; IZUMO3
    protein kinase binding SCN5A; GHR; TRAF2; EEF1A2; HSP90AB1; TENC1; TPRKB; NSF; TBC1D14; SFN
    protein tyrosine kinase activity LTK; KIT; FGR; EPHB4B; FGFR3; MAP2K5; DYRK2; NEK1; MET; CSK
    protein tyrosine kinase inhibitor activity IBTK; GNB2L1; FGFR1OP

    FGFR1OP has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FGFR1OP here. Most of them are supplied by our site. Hope this information will be useful for your research of FGFR1OP.

    VASP; CEP19; PPP2CB; CTGF; CEP350; PACS1; NAGK; CEP350; CCHCR1; Lrrcc1; TBC1D31; PCM1; CSPP1; CCDC14

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