Recombinant Human FGFR1OP Protein, GST-tagged

• Cat.No.: FGFR1OP-4125H
• Product Overview: Human FGFR1OP full-length ORF ( AAH11902, 1 a.a. - 379 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a largely hydrophilic protein postulated to be a leucine-rich protein family member. A t(6;8)(q27;p11) chromosomal translocation, fusing this gene and the fibroblast growth factor receptor 1 (FGFR1) gene, has been found in cases of myeloproliferative disorder. The resulting chimeric protein contains the N-terminal leucine-rich region of this encoded protein fused to the catalytic domain of FGFR1. This gene is thought to play an important role in normal proliferation and differentiation of the erythroid lineage. Alternatively spliced transcript variants that encode different proteins have been identified. [provided by RefSeq
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 67.43 kDa
• AA Sequence: MAATAAAVVAEEDTELRDLLVQTLE NSGVLNRIKAELRAAVFLALEEQEK VENKTPLVNESLRKFLNTKDGRLVA SLVAEFLQFFNLDFTLAVFQPETST LQGLEGRENLARDLGIIEAEGTVGG PLLLEVIRRCQQKEKGPTTGEGALD LSDVHSPPKSPEGKTSAQTTPSKKA NDEANQSDTSVSLSEPKSKSSLHLL SHETKIGSFLSNRTLDGKDKAGLCP DEDDMEGDSFFDDPIPKPEKTYGLR NEPRKQAGSLASLSDAPPLKSGLSS LAGAPSLKDSESKRGNTVLKDLKLI SDKIGSLGLGTGEDDDYVDDFNSTS HRSEKSEISIGEEIEEDLSVEIDDI NTSDKLDDLTQDLTVSQLSDVADYL EDVA
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: FGFR1OP FGFR1 oncogene partner [ Homo sapiens ]
• Official Symbol: FGFR1OP
• Synonyms: FGFR1OP; FGFR1 oncogene partner; FOP; fibroblast growth factor receptor 1 oncogene partner
• Gene ID: 11116
• mRNA Refseq: NM_007045
• Protein Refseq: NP_008976
• MIM: 605392
• UniProt ID: O95684