• Official Full Name

    fucosyltransferase 4 (alpha (1,3) fucosyltranasferase,myeloid-specific)

  • Overview

    The product of this gene transfers fucose to N-acetyllactosamine polysaccharides to generate fucosylated carbohydrate structures. It catalyzes the synthesis of the non-sialylated antigen, Lewis x (CD15).
  • Synonyms

    LeX; CD15; ELFT; FCT3A; FUTIV; SSEA-1; FUC-TIV; FUT4; alpha-(1,3)-fucosyltransferase; Lewis X; fucT-IV; OTTHUMP 00000236888; fucosyltransferase IV; ELAM ligand fucosyltransferase; ELAM-1 ligand fucosyltransferase; galactoside 3-L-fucosyltransferase; stage-specific embryonic antigen 1;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • E.coli
  • E.Coli or Yeast
  • HEK293
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • C
  • His
  • GST
  • His (Fc)
  • Avi
  • His|T7
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human FUT4-3288H Recombinant Human FUT4, His-tagged E.Coli or Yeast His 530
Human FUT4-13044H Recombinant Human FUT4, His-tagged E.coli His 174-407a.a.
Human FUT4-4166H Recombinant Human FUT4 Protein (Gly173-Arg530), C-His tagged Mammalian cells C-His Gly173-Arg530
Human FUT4-4563H Recombinant Human FUT4 Protein, GST-tagged Wheat Germ GST
Human FUT4-043H Recombinant Human FUT4 Protein, C-His-tagged E.coli C-His
Human FUT4-0700H Recombinant Human FUT4 Protein (Asp264-Thr497), N-His tagged E.coli N-His Asp264-Thr497
Mouse FUT4-6093M Recombinant Mouse FUT4 Protein Mammalian Cell His
Mouse Fut4-1447M Recombinant Mouse Fut4 protein, His & T7-tagged E.coli His/T7 Val144~Phe389 (Accession # Q11127)
Mouse FUT4-3393M Recombinant Mouse FUT4 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse FUT4-3393M-B Recombinant Mouse FUT4 Protein Pre-coupled Magnetic Beads HEK293
Chicken FUT4-3134C Recombinant Chicken FUT4 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

FUT4 involved in several pathways and played different roles in them. We selected most pathways FUT4 participated on our site, such as Other types of O-glycan biosynthesis, Glycosphingolipid biosynthesis - lacto and neolacto series, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with FUT4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Other types of O-glycan biosynthesisST3GAL3;RFNG;POFUT2;EOGT;FUT9A;B3GALT4;B3GAT1;B3GALTLB;CHST10
Glycosphingolipid biosynthesis - lacto and neolacto seriesB3GALT5;B4GALT3;FUT5;B3GALT2;B4GALT1;GCNT2;FUT7;FUT3;B3GNT5B

FUT4 has several biochemical functions, for example, alpha-(1->3)-fucosyltransferase activity, fucosyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by FUT4 itself. We selected most functions FUT4 had, and list some proteins which have the same functions with FUT4. You can find most of the proteins on our site.

Function Related Protein
alpha-(1->3)-fucosyltransferase activityFUT3;FUT10;GTDC2;FUT6;FUT7;POMGNT2;POC1BL;FUT4;FUT9
fucosyltransferase activityFT2;PIGB;FT1;DPY19L1;FUT9D;POC1BL;UGGT1;FUT9A;B3GNTL1

FUT4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FUT4 here. Most of them are supplied by our site. Hope this information will be useful for your research of FUT4.

Research Area

Related articles

Shan, X; Aziz, F; et al. Ginsenoside Rg3-induced EGFR/MAPK pathway deactivation inhibits melanoma cell proliferation by decreasing FUT4/LeY expression. INTERNATIONAL JOURNAL OF ONCOLOGY 46:1667-1676(2015).
Poulain, M; Frydman, N; et al. Involvement of doublesex and mab-3-related transcription factors in human female germ cell development demonstrated by xenograft and interference RNA strategies. MOLECULAR HUMAN REPRODUCTION 20:960-971(2014).
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