fut4

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fut4

Official Full Name fucosyltransferase 4 (alpha (1,3) fucosyltranasferase,myeloid-specific)
Background The product of this gene transfers fucose to N-acetyllactosamine polysaccharides to generate fucosylated carbohydrate structures. It catalyzes the synthesis of the non-sialylated antigen, Lewis x (CD15).
Synonyms LeX; CD15; ELFT; FCT3A; FUTIV; SSEA-1; FUC-TIV; FUT4; alpha-(1,3)-fucosyltransferase; Lewis X; fucT-IV; OTTHUMP 00000236888; fucosyltransferase IV; ELAM ligand fucosyltransferase; ELAM-1 ligand fucosyltransferase; galactoside 3-L-fucosyltransferase; stage-specific embryonic antigen 1
    • Species :
    • Chicken
    • Human
    • Mouse
    • Source :
    • E.coli
    • E.Coli or Yeast
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • T7
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human FUT4-13044H Recombinant Human FUT4, His-tagged E.coli His
    Human FUT4-3288H Recombinant Human FUT4, His-tagged E.Coli or Yeast His
    Human FUT4-4563H Recombinant Human FUT4 Protein, GST-tagged Wheat Germ GST
    Mouse Fut4-1447M Recombinant Mouse Fut4 protein, His & T7-tagged E.coli His/T7
    Mouse FUT4-6093M Recombinant Mouse FUT4 Protein Mammalian Cell His
    Chicken FUT4-3134C Recombinant Chicken FUT4 Mammalian Cell His

    fut4 involved in several pathways and played different roles in them. We selected most pathways fut4 participated on our site, such as Other types of O-glycan biosynthesis, Glycosphingolipid biosynthesis - lacto and neolacto series, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with fut4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Other types of O-glycan biosynthesis FUT9A; OGT; POMT1; B4GALT2; B4GALT1; POFUT1; POMT2; C3orf64; B3GALT4; B3GAT1A
    Glycosphingolipid biosynthesis - lacto and neolacto series B4GALT2; B3GNTL2; ST8SIA1; B3GNT1; ST3GAL3; ST3GAL4; B4GALT4; FUT3; FUT5; B3GNT3
    Metabolic pathways HSD17B4; PGAM1; NMNAT1; MVK; ACMSD; COQ6; CES1; UGT1A7C; GNPDA2; B3GALT2

    fut4 has several biochemical functions, for example, alpha-(1->3)-fucosyltransferase activity, fucosyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by fut4 itself. We selected most functions fut4 had, and list some proteins which have the same functions with fut4. You can find most of the proteins on our site.

    Function Related Protein
    alpha-(1->3)-fucosyltransferase activity FUT9; PIGB; FUT4; DPY19L1; POMGNT2; GLT8D1; FUT3; B3GNT9; 4931440L10Rik; B3GNTL1
    fucosyltransferase activity B3GNT9-PS; FUT9A; FUT6; DPY19L4; FUT9B; FT2; PIGB; GALNTL4; FUT2; FUT1

    fut4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with fut4 here. Most of them are supplied by our site. Hope this information will be useful for your research of fut4.

    Shan, X; Aziz, F; et al. Ginsenoside Rg3-induced EGFR/MAPK pathway deactivation inhibits melanoma cell proliferation by decreasing FUT4/LeY expression. INTERNATIONAL JOURNAL OF ONCOLOGY 46:1667-1676(2015).
    Poulain, M; Frydman, N; et al. Involvement of doublesex and mab-3-related transcription factors in human female germ cell development demonstrated by xenograft and interference RNA strategies. MOLECULAR HUMAN REPRODUCTION 20:960-971(2014).

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