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Official Full Name frizzled family receptor 1
Background Members of the frizzled gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins.The FZD1 protein contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, 7 transmembrane domains, and a C-terminal PDZ domain-binding motif.The FZD1 transcript is expressed in various tissues.
Synonyms FZD1; frizzled family receptor 1; frizzled (Drosophila) homolog 1 , frizzled 1, seven transmembrane spanning receptor , frizzled homolog 1 (Drosophila); frizzled-1; DKFZp564G072; frizzled; Drosophila; homolog of; 1; Wnt receptor; fz-1; fzE1; hFz1; frizz
    • Species :
    • Chicken
    • Human
    • Mouse
    • Zebrafish
    • Source :
    • E.coli
    • Human Cell
    • Mammalian Cell
    • Mammalian cells
    • Tag :
    • Fc
    • His
    • T7
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human FZD1-1238H Recombinant Human FZD1 protein, His & T7-tagged E.coli His/T7
    Mouse Fzd1-1014M Recombinant Mouse Fzd1 Protein, Fc Chimera Mammalian cells Fc
    Mouse Fzd1-1239M Recombinant Mouse Fzd1 protein, His & T7-tagged E.coli His/T7
    Mouse Fzd1-2292M Recombinant Mouse Fzd1, His tagged Human Cell His
    Mouse FZD1-2633MCL Recombinant Mouse FZD1 cell lysate Human Cell N/A
    Chicken FZD1-2223C Recombinant Chicken FZD1 Mammalian Cell His
    Zebrafish FZD1-7095Z Recombinant Zebrafish FZD1 Mammalian Cell His

    Fzd1 involved in several pathways and played different roles in them. We selected most pathways Fzd1 participated on our site, such as Wnt signaling pathway, Hippo signaling pathway, Signaling pathways regulating pluripotency of stem cells, which may be useful for your reference. Also, other proteins which involved in the same pathway with Fzd1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Wnt signaling pathway SENP2; FZD8B; PPP3R1; RHOAA; DKK1B; MAPK10; RAC3A; TCF7; PPP3R1B; WNT5B
    Hippo signaling pathway BMP7; TEAD2; TEAD4; ACTB; CRB1; YWHAZ; BMPR1B; PPP2CB; BMP8B; AREG
    Signaling pathways regulating pluripotency of stem cells FZD7; INHBB; PCGF3; ZIC3; WNT6; ESRRB; SMAD2; STAT3; GSK3B; FZD8
    HTLV-I infection SLC25A31; H2-AA; RAN; CDC16; VAC14; CD3G; HLA-B; WNT5A; WNT1; CDC26
    Pathways in cancer HRAS; HDAC1; TPR; CCNA1; PDGFB; Casp3; LAMB2; GLI1; RXRA; STAT3
    Proteoglycans in cancer PTPN11; WNT2; NRAS; IGF1; PRKACB; RPS6KB1; MAP2K1; SDC1; PDPK1; CAV3
    Basal cell carcinoma WNT4; WNT16; PTCH2; TCF7; FZD6; TRP53; WNT8B; WNT1; GSK3B; TCF7L2

    Fzd1 has several biochemical functions, for example, G-protein coupled receptor activity, PDZ domain binding, Wnt-activated receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Fzd1 itself. We selected most functions Fzd1 had, and list some proteins which have the same functions with Fzd1. You can find most of the proteins on our site.

    Function Related Protein
    G-protein coupled receptor activity AGTR1B; VMN1R46; FZD2; OLFR502; GHSR; GPR1; EDNRAB; GPR171; MRGPRA8; GRM8
    PDZ domain binding ARHGAP29; BAIAP2; ACCN3; NSF; GRID2; DLG1; LLGL2; PROSAPIP1; LPAR2; Fzd4
    Wnt-activated receptor activity FZD7; FZD8A; FZD6; FZD8B; FZD5; FZD10; FZD8; LRP5L; Fzd4; FZD3
    Wnt-protein binding Fzd4; SZL; LRP6; FZD8; SETD6; FZD5; PTPRO; LRP5; ROR1; LRP2A
    frizzled binding RNF43; DVL3; WNT3A; MYOC; WNT1; WNT7A; SDCBP; WNT8B; NDP; DVL1B
    identical protein binding SDK2; GLUL; C10orf88; GOT1; CHEK2; VWA2; ALK; CLDN20; C1QL4; INHBA
    protein heterodimerization activity CEBPE; CHRNB2; KCNN1; HER11; IRAK3; H2AFB3; PML; UBA2; TXLNG; DRAP1
    protein homodimerization activity TARS; BCL2L1; UPK1A; BCL2A; DROSHA; TDG; G6PDX; GCH1; GCA; STK4
    receptor binding ANXA1; UFD1L; HLA-B; SEMA4D; MAG; CCL15; GNB2L1; MATK; HLA-F; PKD2
    signal transducer activity PTGER1A; GOLT1B; MALT1; GNG4; TAAR13C; OLFCW1; VMN1R47; GULP1; OLFR867; OLFR1013
    transmembrane signaling receptor activity NRXN3; IL11RA; FZD1; TNFRSF10D; FZD7A; TLR6; SPN; CD97; SIGLEC8; CD3G

    Fzd1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Fzd1 here. Most of them are supplied by our site. Hope this information will be useful for your research of Fzd1.

    Blondeau, JJC; Deng, M; et al. Identification of novel long non-coding RNAs in clear cell renal cell carcinoma. CLINICAL EPIGENETICS 7:-(2015).
    Wang, YH; Motoji, T; et al. Knockdown of a Wnt Receptor FZD1 reduces MDR1/P-Glycoprotein Expression in Human Leukemia Cells through the Wnt/beta-Catenin Signaling Pathway. BLOOD 124:-(2014).

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