FZD2 Protein


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Official Full Name frizzled family receptor 2
Background This intronless gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the wingless type MMTV integration site family of signaling proteins. This gene encodes a protein that is coupled to the beta-catenin canonical signaling pathway. Competition between the wingless-type MMTV integration site family, member 3A and wingless-type MMTV integration site family, member 5A gene products for binding of this protein is thought to regulate the beta-catenin-dependent and -independent pathways.
Synonyms FZD2; frizzled family receptor 2; frizzled (Drosophila) homolog 2 , frizzled 2, seven transmembrane spanning receptor , frizzled homolog 2 (Drosophila); frizzled-2; Frizzled homolog 2; Frizzled2; Fz 2; Fz-2; Fz2; FZD 2; FZD2_HUMAN; FzE 2; FzE2; hFz 2; hFz2; frizzled 2, seven transmembrane spanning receptor
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Mammalian cells
    • Wheat Germ
    • Tag :
    • Fc
    • GST
    • His
    • human
    • IgG1
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human FZD2-2612H Recombinant Human FZD2 protein, His-tagged E.coli His
    Human FZD2-13065H Recombinant Human FZD2, GST-tagged E.coli GST
    Human FZD2-135H Recombinant Human FZD2 protein, Fc-tagged HEK293 human/IgG1/Fc
    Human FZD2-26287TH Recombinant Human FZD2 Wheat Germ N/A
    Human FZD2-321H Recombinant Human FZD2 protein, Fc-tagged HEK293 human/IgG1/Fc
    Human FZD2-4591H Recombinant Human FZD2 Protein, GST-tagged Wheat Germ GST
    Mouse Fzd2-380M Recombinant Mouse Fzd2 Protein, Fc-tagged HEK293 Fc
    Mouse Fzd2-585M Recombinant Mouse Frizzled Homolog 2 (Drosophila), Fc-tagged Mammalian cells Fc
    Rat FZD2-2429R Recombinant Rat FZD2 Protein Mammalian Cell His
    Chicken FZD2-5795C Recombinant Chicken FZD2 Mammalian Cell His
    Zebrafish FZD2-8756Z Recombinant Zebrafish FZD2 Mammalian Cell His

    FZD2 involved in several pathways and played different roles in them. We selected most pathways FZD2 participated on our site, such as Wnt signaling pathway, Hippo signaling pathway, Signaling pathways regulating pluripotency of stem cells, which may be useful for your reference. Also, other proteins which involved in the same pathway with FZD2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Wnt signaling pathway SFRP1A; CXXC4; CCND3; PRKACG; PRKCA; DKK1B; TBL1X; RAC1B; MAPK9; FZD7B
    Hippo signaling pathway CTGF; ID2; LATS2; WNT10B; NKD1; FZD1; FZD5; WNT7A; YWHAG; AXIN1
    Signaling pathways regulating pluripotency of stem cells BMP2; PCGF6; LIF; HAND1; FZD9; WNT7B; MAPK12; FZD5; AXIN2; PIK3R3
    Melanogenesis KITA; CALM3; PLCB2; HRASA; GNAI1; WNT1; CREB1A; MAPK3; DVL3A; FZD1
    Pathways in cancer FGF10; NTRK1; VHL; SMAD3; CCNA1; PTGER2; LAMC1; PIK3R5; RAF1; RASSF5
    Proteoglycans in cancer ROCK2; Fasl; RHOA; NANOG; NUDT16L1; PLCE1; CDC42; CD44; WNT5A; MAPK11
    Basal cell carcinoma TCF7; FZD10; FZD3; DVL3; WNT7A; Shh; FZD9; TP53; FZD6; WNT2B

    FZD2 has several biochemical functions, for example, G-protein coupled receptor activity, PDZ domain binding, Wnt-activated receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by FZD2 itself. We selected most functions FZD2 had, and list some proteins which have the same functions with FZD2. You can find most of the proteins on our site.

    Function Related Protein
    G-protein coupled receptor activity TAAR14L; OLFCG3; RGRA; GPR34A; TAAR13D; OR8U1; GPR34L; HCRTR1; TMTOPS3A; LPAR1
    PDZ domain binding SSTR2; ERC1; SNTA1; GJA1; ATP2B1B; LNX1; TBC1D10A; ATP2B3B; PTENB; CADM1
    Wnt-activated receptor activity FZD3B; FZD8A; FZD7A; FZD7; FZD9B; FZD5; LRP5; FZD2; FZD8; FZD8B
    Wnt-protein binding LRP5L; FZD7; CTHRC1; FZD1; WLS; SFRP2; SFRP1B; SFRP1; PTPRO; FRZB
    protein binding PSMC2; EAF2; SESN2; UHRF2; HELZ2; GNG10; FAM96B; GGACT; NTN4; CCNB1IP1

    FZD2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FZD2 here. Most of them are supplied by our site. Hope this information will be useful for your research of FZD2.

    Fyn; STAT3; C1qa

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