|Official Full Name||frizzled family receptor 3|
|Background||This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. The function of this protein is unknown, although it may play a role in mammalian hair follicle development. Alternative splicing results in multiple transcript variants. This gene is a susceptibility locus for schizophrenia.|
|Synonyms||FZD3; frizzled family receptor 3; frizzled (Drosophila) homolog 3 , frizzled 3, seven transmembrane spanning receptor , frizzled homolog 3 (Drosophila); frizzled-3; frizzled homolog 3; frizzled 3, seven transmembrane spanning receptor; Fz-3;|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
FZD3 involved in several pathways and played different roles in them. We selected most pathways FZD3 participated on our site, such as Wnt signaling pathway, Hippo signaling pathway, Signaling pathways regulating pluripotency of stem cells, which may be useful for your reference. Also, other proteins which involved in the same pathway with FZD3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Wnt signaling pathway||PRKACBA; PRICKLE1; MAPK8; PLCB3; EP300; ROCK2; WNT2BB; FBXW11B; TCF7L1A; CAMK2A|
|Hippo signaling pathway||INADL; BIRC2; PARD6B; FZD1; WNT10B; BMP6; APC2; TEAD3; WNT2B; TGFBR1|
|Signaling pathways regulating pluripotency of stem cells||ID4; KRAS; PAX6; ACVR2A; RAF1; BMI1; BMPR1A; AKT1; HAND1; PIK3R2|
|Melanogenesis||KIT; PRKACBB; CAMK2B; WNT2; FZD1; CALM1A; FZD8; KRAS; KITLGA; DCT|
|HTLV-I infection||PDGFB; HLA-A; BAX; GSK3B; ELK4; POLE; PDGFRA; SPI1; HLA-DMA; HLA-DRB4|
|Pathways in cancer||MSH2; FGFR3; ITGB1; FZD6; RAC1; RARB; GNAI2; VHL; TGFB2; BCR|
|Proteoglycans in cancer||MRAS; CBLB; WNT1; CAMK2B; PPP1R12B; CAMK2A; SDC2; CAV3; GPC1; RPS6KB1|
|MicroRNAs in cancer||DICER1; MDM2; PLAU; MAPK1; HRAS; TNC; SOCS1; HOXD10; TP53; TRIM71|
|Basal cell carcinoma||WNT16; GLI2; WNT8B; TCF7L2; DVL3; STK36; TRP53; WNT9B; TCF7; FZD1|
FZD3 has several biochemical functions, for example, G-protein coupled receptor activity, PDZ domain binding, Wnt-activated receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by FZD3 itself. We selected most functions FZD3 had, and list some proteins which have the same functions with FZD3. You can find most of the proteins on our site.
|G-protein coupled receptor activity||OLFR1013; OLFR24; PARAPINOPSINB; RXFP2B; TAAR1B; CXCR3.2; EMR2; GPR55; LPAR4; GPR97|
|PDZ domain binding||USHBP1; NSF; EXOC4; BAIAP2; SSTR2; SLC22A5; ATP2B1; ARHGAP29; CXADR; ARHGEF16|
|Wnt-activated receptor activity||FZD5; FZD6; LRP6; LRP2A; FZD7B; FZD8A; FZD2; FZD9B; FZD9; FZD3B|
|Wnt-protein binding||LRP6; FZD9; FZD5; EVLA; PORCN; PTPRO; SFRP1A; FZD7; SETD6; FZD8A|
|protein binding||TMEM67; GP6; AHNAK2; MPZL1; GTF2A2; RBM14; AP1S2; EIF3B; IKZF1; EIF6|
FZD3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FZD3 here. Most of them are supplied by our site. Hope this information will be useful for your research of FZD3.
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