FZD3 involved in several pathways and played different roles in them. We selected most pathways FZD3 participated on our site, such as Wnt signaling pathway, Hippo signaling pathway, Signaling pathways regulating pluripotency of stem cells, which may be useful for your reference. Also, other proteins which involved in the same pathway with FZD3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name |
Pathway Related Protein |
| Wnt signaling pathway |
PRKACBA; PRICKLE1; MAPK8; PLCB3; EP300; ROCK2; WNT2BB; FBXW11B; TCF7L1A; CAMK2A |
| Hippo signaling pathway |
INADL; BIRC2; PARD6B; FZD1; WNT10B; BMP6; APC2; TEAD3; WNT2B; TGFBR1 |
| Signaling pathways regulating pluripotency of stem cells |
ID4; KRAS; PAX6; ACVR2A; RAF1; BMI1; BMPR1A; AKT1; HAND1; PIK3R2 |
| Melanogenesis |
KIT; PRKACBB; CAMK2B; WNT2; FZD1; CALM1A; FZD8; KRAS; KITLGA; DCT |
| HTLV-I infection |
PDGFB; HLA-A; BAX; GSK3B; ELK4; POLE; PDGFRA; SPI1; HLA-DMA; HLA-DRB4 |
| Pathways in cancer |
MSH2; FGFR3; ITGB1; FZD6; RAC1; RARB; GNAI2; VHL; TGFB2; BCR |
| Proteoglycans in cancer |
MRAS; CBLB; WNT1; CAMK2B; PPP1R12B; CAMK2A; SDC2; CAV3; GPC1; RPS6KB1 |
| MicroRNAs in cancer |
DICER1; MDM2; PLAU; MAPK1; HRAS; TNC; SOCS1; HOXD10; TP53; TRIM71 |
| Basal cell carcinoma |
WNT16; GLI2; WNT8B; TCF7L2; DVL3; STK36; TRP53; WNT9B; TCF7; FZD1 |
FZD3 has several biochemical functions, for example, G-protein coupled receptor activity, PDZ domain binding, Wnt-activated receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by FZD3 itself. We selected most functions FZD3 had, and list some proteins which have the same functions with FZD3. You can find most of the proteins on our site.
| Function |
Related Protein |
| G-protein coupled receptor activity |
OLFR1013; OLFR24; PARAPINOPSINB; RXFP2B; TAAR1B; CXCR3.2; EMR2; GPR55; LPAR4; GPR97 |
| PDZ domain binding |
USHBP1; NSF; EXOC4; BAIAP2; SSTR2; SLC22A5; ATP2B1; ARHGAP29; CXADR; ARHGEF16 |
| Wnt-activated receptor activity |
FZD5; FZD6; LRP6; LRP2A; FZD7B; FZD8A; FZD2; FZD9B; FZD9; FZD3B |
| Wnt-protein binding |
LRP6; FZD9; FZD5; EVLA; PORCN; PTPRO; SFRP1A; FZD7; SETD6; FZD8A |
| protein binding |
TMEM67; GP6; AHNAK2; MPZL1; GTF2A2; RBM14; AP1S2; EIF3B; IKZF1; EIF6 |
FZD3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FZD3 here. Most of them are supplied by our site. Hope this information will be useful for your research of FZD3.
SDCBP
