FZD5

  • Official Full Name

    frizzled family receptor 5

  • Overview

    Members of the frizzled gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins.The FZD5 protein is believed to be the receptor for the Wnt5A ligand.
  • Synonyms

    FZD5; frizzled family receptor 5; C2orf31, chromosome 2 open reading frame 31 , frizzled (Drosophila) homolog 5 , frizzled 5, seven transmembrane spanning receptor , frizzled homolog 5 (Drosophila); frizzled-5; DKFZP434E2135; HFZ5; fz-5; fzE5; Wnt rec;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Homo sapiens (Human)
  • Human
  • Mouse
  • Mus musculus (Mouse)
  • Rat
  • Rattus norvegicus (Rat)
  • Xenopus laevis (African clawed frog)
  • Zebrafish
  • CHO
  • E.coli
  • E.coli expression system
  • HEK293
  • Human Cell
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • C
  • hFc
  • Fc
  • Fc Chimera
  • Fc|His
  • GST
  • His
  • His (Fc)
  • Avi
  • Flag
  • human|IgG1|Fc
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human FZD5-244H Active Recombinant Human FZD5, Fc Chimera Mammalian cells Fc Chimera
Human FZD5-536H Active Recombinant Human FZD5 Protein, Fc Chimera CHO Fc
Human FZD5-13068H Recombinant Human FZD5, His-tagged E.coli His C-term-62a.a.
Human FZD5-713H Recombinant Human FZD5, Fc-His tagged Human Cell Fc/His
Human FZD5-167H Recombinant Human FZD5 protein, Fc-tagged HEK293 human/IgG1/Fc Ala27-Pro167
Human FZD5-3173H Recombinant Human FZD5 protein, His-tagged HEK293 His Met1-Pro167
Human FZD5-2388HCL Recombinant Human FZD5 cell lysate Human Cell N/A
Human FZD5-4595H Recombinant Human FZD5 Protein, GST-tagged Wheat Germ GST
Human FZD5-5085HF Recombinant Full Length Human FZD5 Protein, GST-tagged In Vitro Cell Free System GST 585 amino acids
Human FZD5-189H-B Recombinant Human FZD5 Protein Pre-coupled Magnetic Beads HEK293
Human FZD5-1112HFL Recombinant Human FZD5 protein, His&Flag-tagged HEK293 His&Flag 1-585 aa
Human FZD5-189H Recombinant Human FZD5 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human FZD5-257H Recombinant Human FZD5 Protein, Fc-tagged HEK293 Fc 585
Human FZD5-1438H Recombinant Human FZD5 protein, Fc-tagged HEK293 Fc Ala27-Pro167
Mouse Fzd5-8681M Recombinant Mouse Fzd5, Fc tagged CHO His
Mouse FZD5-001MCL Recombinant Mouse FZD5 cell lysate CHO N/A
Mouse FZD5-1280M Recombinant Mouse FZD5 protein(Met1-Pro167), hFc-tagged CHO C-hFc Met1-Pro167
Rat FZD5-2431R Recombinant Rat FZD5 Protein Mammalian Cell His
Rat FZD5-2087R-B Recombinant Rat FZD5 Protein Pre-coupled Magnetic Beads HEK293
Rat FZD5-2087R Recombinant Rat FZD5 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Homo sapiens (Human) RFL27056HF Recombinant Full Length Human Frizzled-5(Fzd5) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (27-585)
Mus musculus (Mouse) RFL8244MF Recombinant Full Length Mouse Frizzled-5(Fzd5) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (27-585)
Rattus norvegicus (Rat) RFL32401RF Recombinant Full Length Rat Frizzled-5(Fzd5) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (27-585)
Xenopus laevis (African clawed frog) RFL19746XF Recombinant Full Length Xenopus Laevis Frizzled-5(Fzd5) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (27-559)
Zebrafish FZD5-8754Z Recombinant Zebrafish FZD5 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource
  • FZD5 Related Signal Pathway

FZD5 involved in several pathways and played different roles in them. We selected most pathways FZD5 participated on our site, such as Wnt signaling pathway, Hippo signaling pathway, Signaling pathways regulating pluripotency of stem cells, which may be useful for your reference. Also, other proteins which involved in the same pathway with FZD5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Wnt signaling pathwayAXIN2;PRKCG;LRP5;NFATC2;TBL1XR1;PRICKLE1;VANGL2;DKK4;CHD8
Hippo signaling pathwaySMAD3;LLGL2;NF2;PPP1CB;WNT7B;MOB1A;FZD2;ITGB2;FZD7
Signaling pathways regulating pluripotency of stem cellsLIFR;WNT9B;AXIN2;SMARCAD1;KRAS;ID1;LEFTY2;WNT11;MAPK13
MelanogenesisWNT16;PRKCB;GSK3B;CREB1A;KITA;TYRP1;TYRP1B;CALM2A;FZD7B
HTLV-I infectionXBP1;IL1R2;BCL2L1;SLC25A4;FZD1;EGR2;POLD4;ATF4;CALR
Pathways in cancerNFKB1;RASSF5;LAMA3;GNG11;SMAD4;TFG;XIAP;PLEKHG5;NKX3-1
Proteoglycans in cancerTLR4;WNT9A;MAPK13;PRKCG;FN1;FLNA;MAP2K2;PXN;PPP1R12B
Basal cell carcinomaDVL1;SMO;APC2;FZD8;WNT11;GLI2;GLI3;FZD3;AXIN2

FZD5 has several biochemical functions, for example, G-protein coupled receptor activity, Wnt-activated receptor activity, Wnt-protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FZD5 itself. We selected most functions FZD5 had, and list some proteins which have the same functions with FZD5. You can find most of the proteins on our site.

Function Related Protein
G-protein coupled receptor activityTAS2R121;OR6K3;MC5RB;MC5RA;OR10A5;OLFR154;MRGPRB1;TAAR12E;TAS2R108
Wnt-activated receptor activityLRP6;FZD2;FZD8B;LRP5L;LRP5;FZD7B;FZD3;Fzd4;FZD9
Wnt-protein bindingSETD6;SMO;SFRP1B;FZD3B;SFRP1A;GM12824;FZD2;Fzd4;FZD6
protein bindingDYNC1LI1;CTSK;ULK2;CHRNA5;SIVA1;DYNLRB1;DNAJC10;ANXA5;CCNB2
protein kinase bindingSPRED2;ARHGEF7;CHEK2;CCNY;H2AFY;TCF7L2;JTB;CCND1;SLC12A4
ubiquitin protein ligase bindingPTPN22;ARIH1;TRAF5;EGR2;SMAD5;TNFRSF14;CUL4A;HSPA1A;MOAP1

FZD5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FZD5 here. Most of them are supplied by our site. Hope this information will be useful for your research of FZD5.

SCYL2; WNT5A; BAMBI; WNT2B; RGS2; GSK3B; ABI3BP; UBTD1; LZTFL1; RPS6KA6; LRRK2

Gene Family

GPCRs

Research Area

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