Recombinant Human FZD5, His-tagged

• Cat.No.: FZD5-13068H
• Product Overview: Recombinant Human FZD5 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: C-term-62a.a.
• Description: Members of the frizzled gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD5 protein is believed to be the receptor for the Wnt5A ligand.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: FZD5 frizzled family receptor 5 [ Homo sapiens ]
• Official Symbol: FZD5
• Synonyms: FZD5; frizzled family receptor 5; C2orf31, chromosome 2 open reading frame 31 , frizzled (Drosophila) homolog 5 , frizzled 5, seven transmembrane spanning receptor , frizzled homolog 5 (Drosophila); frizzled-5; DKFZP434E2135; HFZ5; fz-5; fzE5; Wnt receptor; seven-transmembrane receptor frizzled-5; frizzled 5, seven transmembrane spanning receptor; C2orf31; MGC129692; DKFZp434E2135
• Gene ID: 7855
• mRNA Refseq: NM_003468
• Protein Refseq: NP_003459
• MIM: 601723
• UniProt ID: Q13467
• Chromosome Location: 2q33.3
• Pathway: Basal cell carcinoma, organism-specific biosystem; Basal cell carcinoma, conserved biosystem; Canonical Wnt signaling pathway, organism-specific biosystem; Class B/2 (Secretin family receptors), organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; HTLV-I infection, organism-specific biosystem; HTLV-I infection, conserved biosystem
• Function: G-protein coupled receptor activity; PDZ domain binding; Wnt-activated receptor activity; Wnt-activated receptor activity; Wnt-protein binding; protein binding; protein kinase binding; receptor activity; signal transducer activity