Active Recombinant Human FZD5, Fc Chimera

• Cat.No.: FZD5-244H
• Product Overview: Recombinant Human FZD5 (Accession # AAC50385) was produced in Mouse myeloma cell line, NS0-derived.

Specification

• Species: Human
• Source: Mammalian Cells
• Tag: Fc
• Predicted N Terminal: Ala27
• Form: Lyophilized from a 0.2 µm filtered solution in PBS.
• Bio-activity: Measured by its ability to bind biotinylated Wnt-5a in a functional ELISA with an estimated KD <1.5 nM.
• Molecular Mass: Recombinant Human FZD5, Fc Chimera has a calculated MW of 42.5 kDa (monomer). In SDS-PAGE migrates as 55-60 kDa, reducing conditions.
• Purity: >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).

Gene Information

• Gene Name: FZD5 frizzled family receptor 5 [ Homo sapiens ]
• Official Symbol: FZD5
• Synonyms: FZD5; frizzled family receptor 5; C2orf31, chromosome 2 open reading frame 31 , frizzled (Drosophila) homolog 5 , frizzled 5, seven transmembrane spanning receptor , frizzled homolog 5 (Drosophila); frizzled-5; DKFZP434E2135; HFZ5; fz-5; fzE5; Wnt receptor; seven-transmembrane receptor frizzled-5; frizzled 5, seven transmembrane spanning receptor; C2orf31; MGC129692; DKFZp434E2135
• Gene ID: 7855
• mRNA Refseq: NM_003468
• Protein Refseq: NP_003459
• MIM: 601723
• UniProt ID: Q13467
• Chromosome Location: 2q33.3