galnt2

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galnt2

Official Full Name UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2)
Background This gene encodes polypeptide N-acetylgalactosaminyltransferase 2, a member of the GalNAc-transferases family. This family transfers an N-acetyl galactosamine to the hydroxyl group of a serine or threonine residue in the first step of O-linked oligosaccharide biosynthesis. Individual GalNAc-transferases have distinct activities and initiation of O-glycosylation in a cell is regulated by a repertoire of GalNAc-transferases.
Synonyms GALNT2; UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2); polypeptide N-acetylgalactosaminyltransferase 2; GalNAc T2; GalNAc-T2; GALT2_HUMAN; GaNTase 2; Polypeptide GalNAc transferase 2; Polypeptide N acetylgalactosaminyltransferase 2 soluble form; Polypeptide N-acetylgalactosaminyltransferase 2 soluble form; pp GaNTase 2; pp-GaNTase 2; Protein UDP acetylgalactosaminyltransferase 2; Protein-UDP acetylgalactosaminyltransferase 2; UDP GalNAc transferase 2; UDP N acetyl alpha D galactosamine:polypeptide N acetylgalactosaminyltransferase 2; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 2; UDP-GalNAc transferase 2
    • Species :
    • Human
    • Mouse
    • Rhesus Macaque
    • Rhizobia
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Human Cell
    • Mammalian Cell
    • P. pastoris
    • Wheat Germ
    • Tag :
    • Fc
    • GST
    • His
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human GALNT2-1252H Recombinant Human GALNT2 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human GALNT2-13136H Recombinant Human GALNT2, His-tagged E.coli His
    Human GALNT2-229H Recombinant Human GALNT2, His tagged Human Cell Fc
    Human GALNT2-27303TH Recombinant Human GALNT2 Wheat Germ N/A
    Human GALNT2-4698H Recombinant Human GALNT2 Protein P. pastoris N/A
    Human GALNT2-4699H Recombinant Human GALNT2 Protein, GST-tagged Wheat Germ GST
    Human GALNT2-585H Recombinant Human GALNT2 Mammalian Cell His
    Human GALNT2-907HCL Recombinant Human GALNT2 cell lysate Human Cell N/A
    Mouse GALNT2-6185M Recombinant Mouse GALNT2 Protein Mammalian Cell His
    Rhesus Macaque GALNT2-1807R Recombinant Rhesus monkey GALNT2 Protein, His-tagged Mammalian Cell His
    Zebrafish GALNT2-6862Z Recombinant Zebrafish GALNT2 Mammalian Cell His
    Rhizobia GALNT2-4700R Recombinant Rhizobia GALNT2 Protein E.coli N/A

    galnt2 involved in several pathways and played different roles in them. We selected most pathways galnt2 participated on our site, such as Mucin type O-Glycan biosynthesis, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with galnt2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Mucin type O-Glycan biosynthesis GALNT12; GALNTL5; B3GNT6; POC1BL; GCNT3; GALNT13; GALNTL4; GALNT18A; GALNT2; C1GALT1B
    Metabolic pathways ALDH3B2; Amy1; AKR1D1; ST6GALNAC6; NDUFA12; GLCEB; HADHA; ALDOA; PAICS; PCYT1BA

    galnt2 has several biochemical functions, for example, carbohydrate binding, manganese ion binding, polypeptide N-acetylgalactosaminyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by galnt2 itself. We selected most functions galnt2 had, and list some proteins which have the same functions with galnt2. You can find most of the proteins on our site.

    Function Related Protein
    carbohydrate binding FBXO2; GALNT14; LPHN1; KLRB1A; CD209A; GALNT18A; CLEC1B; Il2; LGALSLA; CLEC2B
    manganese ion binding IMPA1; FAM20C; PCK1; PPEF2; PPM1BB; ENDOU; PPM1AA; ARG1; DCP2; XPNPEP1
    polypeptide N-acetylgalactosaminyltransferase activity GALNTL4; GALNTL6; C1GALT1C1; GALNT12; GALNTL2; GALNT4; GALNT1; WBSCR17; GALNT3; GALNT2
    protein binding MRPL12; RINT1; ATP5F1; WBP11; NFKBIE; C1QTNF3; RBM44; NOSTRIN; FRMD7; SYT6

    galnt2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with galnt2 here. Most of them are supplied by our site. Hope this information will be useful for your research of galnt2.

    CCDC155; NOD2; AP4M1; Shoc2; Itgb1; PTPN1; Rab5c; Rad54l; REEP5; Papss1; MMGT1; Tor1aip1; Hspa14; Mis12; AP4S1; Uso1

    Ho, WL; Chou, CH; et al. GALNT2 suppresses malignant phenotypes through IGF-1 receptor and predicts favorable prognosis in neuroblastoma. ONCOTARGET 5:12247-12259(2014).
    Cole, CB; Nikpay, M; et al. Adiposity significantly modifies genetic risk for dyslipidemia. JOURNAL OF LIPID RESEARCH 55:2416-2422(2014).

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