Official Full Name | GATA binding protein 6 |
Background | This gene is a member of a small family of zinc finger transcription factors that play an important role in the regulation of cellular differentiation and organogenesis during vertebrate development. This gene is expressed during early embryogenesis and localizes to endo- and mesodermally derived cells during later embryogenesis and thereby plays an important role in gut, lung, and heart development. Mutations in this gene are associated with several congenital defects. [provided by RefSeq, Mar 2012] |
Synonyms | GATA6; GATA binding protein 6; transcription factor GATA-6; GATA-binding factor 6; |
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
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GATA6 involved in several pathways and played different roles in them. We selected most pathways GATA6 participated on our site, such as Factors involved in megakaryocyte development and platelet production, Heart Development, Hemostasis, which may be useful for your reference. Also, other proteins which involved in the same pathway with GATA6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Factors involved in megakaryocyte development and platelet production | IRF1B; PHF21A; CABLES2; MAFG; HBBE2; DOCK8; LRRC16A; KIF3B; DOCK10; HBG2 |
Heart Development | NKX2-5; BMP10; NKX2; FOXC1; HEY2; IRX4; SMYD1; HEY1; FOXC2; TBX20 |
Hemostasis | KIFC1; S100A10B; RHOGA; STXBP3A; D-AKAP2; S100A10; BA1; CFHL1; SLC8A2A; CEACAM6 |
Metabolism of proteins | NEU4; CPE; MFGE8; PHC3; MUC4; DNAJB9; B3GNT6; PIGK; TPP1; O3far1 |
Notch-mediated HES/HEY network | GATA1; MYOD1; RCAN1; MYB; GATA6; HES6; CTBP1; HEY1; BGLAP; YY1 |
Surfactant metabolism | SFTPBB; LMCD1; ZDHHC2; CCDC59; SLC34A2A; CTSH; GATA6; GPR116; CKAP4; DMBT1 |
GATA6 has several biochemical functions, for example, RNA polymerase II core promoter sequence-specific DNA binding, RNA polymerase II regulatory region sequence-specific DNA binding, RNA polymerase II repressing transcription factor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GATA6 itself. We selected most functions GATA6 had, and list some proteins which have the same functions with GATA6. You can find most of the proteins on our site.
Function | Related Protein |
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RNA polymerase II core promoter sequence-specific DNA binding | EGR1; FOS; MAZ; GATA1; TFAP2A; WBP2; TAL1; SPI1; MTF1; NR4A2 |
RNA polymerase II regulatory region sequence-specific DNA binding | FOXF1; RORA; DMRT2; ACTN4; NFIL3; NHLH2; ZNF773; JARID2; BCL6AB; ONECUT3 |
RNA polymerase II repressing transcription factor binding | PROL1; PPARA; MTA2; SP1; BBS2; BBS5; MKKS; GTF2A2; BBS10; BBS7 |
RNA polymerase II transcription factor activity, sequence-specific DNA binding | MKX; FOXK1; JUNB; SOX14; TFAP2E; PAX6A; FEV; FOXQ2; HIF1AL2; ZNF444 |
RNA polymerase II transcription factor binding | DHX9; SPOP; GATA6; ZFPM1; GATA2; GFI1B; SPI1; ZFPM2A; T; ANKRD1 |
chromatin binding | EWSR1A; SAFB; ZFP354B; Ar; SMC3; AAAS; ATOH1A; SATB1; RELA; FANCM |
protein binding | CD69; JAG1; SCNN1G; INTS10; CASP2; OIT3; AHCYL2; TRMT12; CCDC42; KCNG3 |
protein kinase binding | DBF4B; PPME1; PPP1R12C; MAP3K5; B4GALT1; STK11IP; GCSAM; CCNL2; SNAP91; CDK5RAP2 |
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding | SOX9; HIF1A; NFATC1; MYF5; SOX7; HNF1B; IRF8; T; NR5A1; NKX2-1 |
transcription factor activity, sequence-specific DNA binding | POU2F1; CREB3L3L; ZIC5; PPARAB; YEATS4; FEV; NR2F5; SALL1A; TEAD3; SIX3 |
transcription factor binding | CREBBP; PPP1R13BA; HES2; POU5F1; SRY; NFATC2; E2F4; LCOR; ENPP2; APBB3 |
transcription regulatory region DNA binding | GABPB2; ARRB1; GRHL1; XRCC6; WNT11; HINFP; PRDM5; TBX21; TBX16; NR1D1 |
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding | AIRE; PAX9; ALX4; FOXF1; SOX17; FEZF2; MAFGB; FOXF2; MYF6; NEUROD2 |
zinc ion binding | TRIM43A; TRIM65; UQCRC1; TAF15; MKRN1; ZZEF1; MLLT6; SIAH1A; ZDHHC1; DNMT1 |
GATA6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GATA6 here. Most of them are supplied by our site. Hope this information will be useful for your research of GATA6.
KLF13; KPNA3; o68769_yerpe
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