Recombinant Human GATA6 Protein, His-tagged
| Cat.No. : | GATA6-046H |
| Product Overview : | Recombinant Human GATA6 Protein with His tag was expressed in E. coli. |
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| Species : | Human |
| Source : | E.coli |
| Tag : | His |
| Description : | GATA proteins comprise a group of transcription factors that are related by the presence of conserved zinc finger DNA-binding domains, which bind directly to the nucleotide sequence core element GATA. There are six vertebrate GATA proteins, designated GATA-1 to GATA-6. GATA-6 plays a critical role in endoderm development. It is essential for development of the heart, gut, and other organs. Knock out of GATA-6 is embryonic lethal due to defects in formation of the heart tube and a failure to develop extraembryonic endoderm. Loss of expression, or loss of nuclear localization of GATA-6 is apparent in a large number of ovarian tumors. |
| Molecular Mass : | ~66 kDa |
| AA Sequence : | HMALTDGGWCLPKRFGAAGADASDSRAFPAREPSTPPSPISSSSSSCSRGGERGPGGASNCGTPQLDTEAAAGPPARSLLLSSYASHPFGAPHGPSAPGVAGPGGNLSSWEDLLLFTDLDQAATASKLLWSSRGAKLSPFAPEQPEEMYQTLAALSSQGPAAYDGAPGGFVHSAAAAAAAAAAASSPVYVPTTRVGSMLPGLPYHLQGSGSGPANHAGGAGAHPGWPQASADSPPYGSGGGAAGGGAAGPGGAGSAAAHVSARFPYSPSPPMANGAAREPGGYAAAGSGGAGGVSGGGSSLAAMGGREPQYSSLSAARPLNGTYHHHHHHHHHHPSPYSPYVGAPLTPAWPAGPFETPVLHSLQSRAGAPLPVPRGPSADLLEDLSESRECVNCGSIQTPLWRRDGTGHYLCNACGLYSKMNGLSRPLIKPQKRVPSSRRLGLSCANCHTTTTTLWRRNAEGEPVCNACGLYMKLHGVPRPLAMKKEGIQTRKRKPKNINKSKTCSGNSNNSIPMTPTSTSSNSDDCSKNTSPTTQPTASGAGAPVMTGAGESTNPENSELKYSGQDGLYIGVSLASPAEVTSSVRPDSWCALALALE |
| Purity : | Transferred into competent cells and the supernatant was purified by NI column affinity chromatography and the purity is > 85% (by SDS-PAGE). |
| Notes : | For research use only, not for use in diagnostic procedure. |
| Storage : | Store at 4 centigrade short term. Aliquot and store at -20 centigrade long term. Avoid freeze-thaw cycles. |
| Storage Buffer : | 0.5M Urea, pH7.4 |
| Gene Name | GATA6 GATA binding protein 6 [ Homo sapiens (human) ] |
| Official Symbol | GATA6 |
| Synonyms | GATA6; GATA binding protein 6; transcription factor GATA-6; GATA-binding factor 6; GATA-binding protein 6; |
| Gene ID | 2627 |
| mRNA Refseq | NM_005257 |
| Protein Refseq | NP_005248 |
| MIM | 601656 |
| UniProt ID | Q92908 |
Not For Human Consumption!
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