Recombinant Human GATA6 Protein, His-tagged

Cat.No. : GATA6-046H
Product Overview : Recombinant Human GATA6 Protein with His tag was expressed in E. coli.
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Description : GATA proteins comprise a group of transcription factors that are related by the presence of conserved zinc finger DNA-binding domains, which bind directly to the nucleotide sequence core element GATA. There are six vertebrate GATA proteins, designated GATA-1 to GATA-6. GATA-6 plays a critical role in endoderm development. It is essential for development of the heart, gut, and other organs. Knock out of GATA-6 is embryonic lethal due to defects in formation of the heart tube and a failure to develop extraembryonic endoderm. Loss of expression, or loss of nuclear localization of GATA-6 is apparent in a large number of ovarian tumors.
Source : E. coli
Species : Human
Tag : His
Molecular Mass : ~66 kDa
AA Sequence : HMALTDGGWCLPKRFGAAGADASDS RAFPAREPSTPPSPISSSSSSCSRG GERGPGGASNCGTPQLDTEAAAGPP ARSLLLSSYASHPFGAPHGPSAPGV AGPGGNLSSWEDLLLFTDLDQAATA SKLLWSSRGAKLSPFAPEQPEEMYQ TLAALSSQGPAAYDGAPGGFVHSAA AAAAAAAAASSPVYVPTTRVGSMLP GLPYHLQGSGSGPANHAGGAGAHPG WPQASADSPPYGSGGGAAGGGAAGP GGAGSAAAHVSARFPYSPSPPMANG AAREPGGYAAAGSGGAGGVSGGGSS LAAMGGREPQYSSLSAARPLNGTYH HHHHHHHHHPSPYSPYVGAPLTPAW PAGPFETPVLHSLQSRAGAPLPVPR GPSADLLEDLSESRECVNCGSIQTP LWRRDGTGHYLCNACGLYSKMNGLS RPLIKPQKRVPSSRRLGLSCANCHT TTTTLWRRNAEGEPVCNACGLYMKL HGVPRPLAMKKEGIQTRKRKPKNIN KSKTCSGNSNNSIPMTPTSTSSNSD DCSKNTSPTTQPTASGAGAPVMTGA GESTNPENSELKYSGQDGLYIGVSL ASPAEVTSSVRPDSWCALALALE
Purity : Transferred into competent cells and the supernatant was purified by NI column affinity chromatography and the purity is > 85% (by SDS-PAGE).
Notes : For research use only, not for use in diagnostic procedure.
Storage : Store at 4 centigrade short term. Aliquot and store at -20 centigrade long term. Avoid freeze-thaw cycles.
Storage Buffer : 0.5M Urea, pH7.4
FACS:
Gene Name : GATA6 GATA binding protein 6 [ Homo sapiens (human) ]
Official Symbol : GATA6
Synonyms : GATA6; GATA binding protein 6; transcription factor GATA-6; GATA-binding factor 6; GATA-binding protein 6;
Gene ID : 2627
mRNA Refseq : NM_005257
Protein Refseq : NP_005248
MIM : 601656
UniProt ID : Q92908

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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