Recombinant Human Growth Differentiation Factor 9

Cat.No. : GDF9-245H
Product Overview : Recombinant human GDF-9 produced inE.coliis a 31.0 kDa non-disulfide-linked homodimer containing two 135 amino acid polypeptide chains.
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Cat. No. : GDF9-245H
Description : GDF-9 is a member of the TGF-β superfamily of growth and differentiation factors, and is highly homologous to GDF-3. Unlike most TGF-family members, GDF-9 and GDF-3 are not disulfide-linked dimers. GDF-3 is expressed in adult bone marrow, spleen, thymus, and adipose tissue. GDF-9 is expressed in oocytes and is required for normal ovarian folliculogenesis.
Source : E.coli.
Purity : > 98% by SDS-PAGE and HPLC analysis.
Endotoxin level : < 0.1 ng per μg of GDF-9.
Stabilizer : None.
Formulation : Lyophilized.
Biologically Activity : Testing in progress.
Reconstitution : The human GDF-9 should be reconstituted in water to a concentration of 0.1-1.0 mg/ml. This solution can be diluted in water or other buffer solutions or stored at -20℃.
Stability : The lyophilized protein is stable for a few weeks at room temperature, but best stored at -20°C. Reconstituted human GDF-9 should be stored in working aliquots at -20°C. Avoid repeated freeze-thaw cycles.
Tag : Non
Gene Name : GDF9 growth differentiation factor 9 [ Homo sapiens ]
Synonyms : GDF9; growth differentiation factor 9; OTTHUMP00000066213; Growth/differentiation factor 9; GDF-9
Gene ID : 2661
mRNA Refseq : NM_005260
Protein Refseq : NP_005251
MIM : 601918
UniProt ID : O60383
Chromosome Location : 5q31.1
Function : cytokine activity; growth factor activity

Not For Human Consumption!

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Customer Reviews (3)

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11/14/2021

    Expertise in peptide synthesis, accelerates our peptide-related projects.

    08/24/2020

      Swift protein quantification, improves data reliability in our experiments.

      01/31/2019

        Outstanding protein-protein interaction studies, boost our research efforts.

        Q&As (7)

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        How does GDF9 influence the proliferation and differentiation of granulosa cells in the ovary? 03/26/2021

        GDF9 stimulates granulosa cell proliferation and differentiation, essential for healthy ovarian function.

        What are the mechanisms by which GDF9 modulates intra-ovarian signaling pathways? 10/12/2020

        GDF9 interacts with intra-ovarian signaling pathways, coordinating follicle development and ovulation.

        How do alterations in GDF9 expression or function affect embryonic development and early pregnancy? 09/17/2020

        Changes in GDF9 expression impact embryonic development and the success of early pregnancy stages.

        What role does GDF9 play in fertility and reproductive outcomes in females? 11/28/2019

        GDF9 significantly impacts female fertility, affecting egg quality and reproductive potential.

        What is the impact of GDF9 mutations on the pathogenesis of ovarian dysfunctions and disorders? 04/28/2019

        Mutations in GDF9 can lead to ovarian disorders, impacting follicle development and female fertility.

        How does GDF9 regulate ovarian follicle development and oocyte maturation? 04/22/2019

        GDF9 is crucial for ovarian follicle growth and oocyte maturation, influencing female fertility.

        How does GDF9 contribute to the regulation of steroidogenesis in ovarian cells? 09/30/2018

        GDF9 regulates steroid hormone production in ovarian cells, influencing reproductive hormone balance.

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