Recombinant Human GDF9 Protein, GST-tagged

• Cat.No.: GDF9-4830H
• Product Overview: Human GDF9 full-length ORF ( NP_005251.1, 1 a.a. - 454 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: Growth factors synthesized by ovarian somatic cells directly affect oocyte growth and function. Growth differentiation factor-9 (GDF9) is expressed in oocytes and is thought to be required for ovarian folliculogenesis. GDF9 is a member of the transforming growth factor-beta superfamily. [provided by RefSeq
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 77.8 kDa
• AA Sequence: MARPNKFLLWFCCFAWLCFPISLGS QASGGEAQIAASAELESGAMPWSLL QHIDERDRAGLLPALFKVLSVGRGG SPRLQPDSRALHYMKKLYKTYATKE GIPKSNRSHLYNTVRLFTPCTRHKQ APGDQVTGILPSVELLFNLDRITTV EHLLKSVLLYNINNSVSFSSAVKCV CNLMIKEPKSSSRTLGRAPYSFTFN SQFEFGKKHKWIQIDVTSLLQPLVA SNKRSIHMSINFTCMKDQLEHPSAQ NGLFNMTLVSPSLILYLNDTSAQAY HSWYSLHYKRRPSQGPDQERSLSAY PVGEEAAEDGRSSHHRHRRGQETVS SELKKPLGPASFNLSEYFRQFLLPQ NECELHDFRLSFSQLKWDNWIVAPH RYNPRYCKGDCPRAVGHRYGSPVHT MVQNIIYEKLDSSVPRPSCVPAKYS PLSVLTIEPDGSIAYKEYEDMIATK CTCR
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: GDF9 growth differentiation factor 9 [ Homo sapiens ]
• Official Symbol: GDF9
• Synonyms: GDF9; growth differentiation factor 9; growth/differentiation factor 9; GDF-9
• Gene ID: 2661
• mRNA Refseq: NM_005260
• Protein Refseq: NP_005251
• MIM: 601918
• UniProt ID: O60383

Reviews

11/14/2021

Expertise in peptide synthesis, accelerates our peptide-related projects.

08/24/2020

Swift protein quantification, improves data reliability in our experiments.

01/31/2019

Outstanding protein-protein interaction studies, boost our research efforts.

Q&As

How does GDF9 influence the proliferation and differentiation of granulosa cells in the ovary?

GDF9 stimulates granulosa cell proliferation and differentiation, essential for healthy ovarian function.

What are the mechanisms by which GDF9 modulates intra-ovarian signaling pathways?

GDF9 interacts with intra-ovarian signaling pathways, coordinating follicle development and ovulation.

How do alterations in GDF9 expression or function affect embryonic development and early pregnancy?

Changes in GDF9 expression impact embryonic development and the success of early pregnancy stages.

What role does GDF9 play in fertility and reproductive outcomes in females?

GDF9 significantly impacts female fertility, affecting egg quality and reproductive potential.

What is the impact of GDF9 mutations on the pathogenesis of ovarian dysfunctions and disorders?

Mutations in GDF9 can lead to ovarian disorders, impacting follicle development and female fertility.

How does GDF9 regulate ovarian follicle development and oocyte maturation?

GDF9 is crucial for ovarian follicle growth and oocyte maturation, influencing female fertility.

How does GDF9 contribute to the regulation of steroidogenesis in ovarian cells?

GDF9 regulates steroid hormone production in ovarian cells, influencing reproductive hormone balance.