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GHRHR

Official Full Name

growth hormone releasing hormone receptor
Overview

This gene encodes a receptor for growth hormone-releasing hormone. Binding of this hormone to the receptor leads to synthesis and release of growth hormone. Mutations in this gene have been associated with isolated growth hormone deficiency (IGHD), also known as Dwarfism of Sindh, a disorder characterized by short stature.
Synonyms

GHRHR; growth hormone releasing hormone receptor; growth hormone-releasing hormone receptor; GHRFR; GHRH R; GHRH receptor; GHRHR_HUMAN; GHRHRpsv; GRF R; GRF receptor; GRFR; Growth hormone releasing factor receptor; Growth hormone-releasing factor receptor; IGHD1B;

Type

Recombinant Proteins
Protein Pre-coupled Magnetic Beads
Assay Kits

Species

Chicken
Human
Mouse
Mus musculus (Mouse)
Rat
Sus scrofa (Pig)

Source

E.coli
E.coli expression system
HEK293
Mammalian Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi
Flag
His|GST
N/A
N

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	GHRHR-7849H	Recombinant Human GHRHR protein, His & GST-tagged	E.coli	His/GST	His23~Lys130 (Accession # Q02643)	Inquiry
Human	GHRHR-29025TH	Recombinant Human GHRHR	Wheat Germ	N/A	110 amino acids	Inquiry
Human	GHRHR-4891H	Recombinant Human GHRHR Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	GHRHR-1108HFL	Recombinant Human GHRHR protein, His&Flag-tagged	HEK293	His&Flag	1-423 aa	Inquiry
Human	GHRHR-2541H	Recombinant Human GHRHR Protein (His23-Lys130), N-GST tagged	E.coli	N-GST	His23-Lys130	Inquiry
Mouse	GHRHR-6341M	Recombinant Mouse GHRHR Protein	Mammalian Cell	His		Inquiry
Mouse	GHRHR-3551M	Recombinant Mouse GHRHR Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	Ghrhr-1576M	Recombinant Mouse Ghrhr Protein, His-tagged	E.coli	N-His	His23-Ile131	Inquiry
Mouse	GHRHR-3551M-B	Recombinant Mouse GHRHR Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rat	GHRHR-2530R	Recombinant Rat GHRHR Protein	Mammalian Cell	His		Inquiry
Rat	GHRHR-2186R-B	Recombinant Rat GHRHR Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rat	GHRHR-2186R	Recombinant Rat GHRHR Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mus musculus (Mouse)	RFL29079MF	Recombinant Full Length Mouse Growth Hormone-Releasing Hormone Receptor(Ghrhr) Protein, His-Tagged	E.coli expression system	His	Full Length of Mature Protein (23-423)	Inquiry
Sus scrofa (Pig)	RFL17658SF	Recombinant Full Length Pig Growth Hormone-Releasing Hormone Receptor(Ghrhr) Protein, His-Tagged	E.coli expression system	His	Full Length of Mature Protein (23-423)	Inquiry
Chicken	GHRHR-3303C	Recombinant Chicken GHRHR	Mammalian Cell	His		Inquiry
Chicken	GHRHR-4487C	Recombinant Chicken GHRHR	Mammalian Cell	His		Inquiry
	Kit-1055	Cathepsin E Activity Assay Kit (Fluorometric)		N/A		Inquiry
	Kit-1254	cAMP GHRHR CHO-K1 GPCR Assay Kit		N/A		Inquiry

Involved Pathway
Protein Function
Interacting Protein
GHRHR Related Articles
GHRHR Related Gene Family

GHRHR involved in several pathways and played different roles in them. We selected most pathways GHRHR participated on our site, such as Neuroactive ligand-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with GHRHR were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Neuroactive ligand-receptor interaction	PTGER4C;TAAR2;TAAR14E;GRM4;TAAR1;ADRB3B;TACR2;CYSLTR2;VIPR1B

GHRHR has several biochemical functions, for example, G-protein coupled receptor activity, growth factor binding, growth hormone-releasing hormone receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GHRHR itself. We selected most functions GHRHR had, and list some proteins which have the same functions with GHRHR. You can find most of the proteins on our site.

Function	Related Protein
G-protein coupled receptor activity	VMN1R44;CHRM5B;OPN5;EMR3;VMN1R49;LANCL1;OLFR50;OLFR688;OLFR13
growth factor binding	LIFR;NKD2;IL6ST;FLT1;FGFBP2;NRP1;FLT4;REG3B;SDCBP
growth hormone-releasing hormone receptor activity	GHSRA;GHRHR;MLNR;GHRHRA;GHSR
peptide hormone binding	OXTR;PTH1RB;ACVR1;PRLR;GALR3;GIPR;NPR1;RXFP2;MAS1
protein binding	UBXN6;XPO1;TRAPPC4;ERP29;CYB561;BIN2;CLDN18;PTH1R;MMS19

GHRHR has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GHRHR here. Most of them are supplied by our site. Hope this information will be useful for your research of GHRHR.

Qi, QE; Xi, QY; et al. Alteration of the miRNA expression profile in male porcine anterior pituitary cells in response to GHRH and CST and analysis of the potential roles for miRNAs in regulating GH. GROWTH HORMONE & IGF RESEARCH 25:66-74(2015).

Kale, S; Budyal, S; et al. A novel gross indel in the growth hormone releasing hormone receptor gene of Indian IGHD patients. GROWTH HORMONE & IGF RESEARCH 24:227-232(2014).