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Official Full Name glucosamine-6-phosphate deaminase 2
Background The protein encoded by this gene is an allosteric enzyme that catalyzes the reversible reaction converting;D-glucosamine-6-phosphate into D-fructose-6-phosphate and ammonium. Variations of this gene have been reported to be;associated with influencing body mass index and susceptibility to obesity. A pseudogene of this gene is located on;chromosome 9. Alternative splicing results in multiple transcript variants that encode different protein isoforms.
Synonyms GNPDA2; glucosamine-6-phosphate deaminase 2; glucosamine-6-phosphate isomerase 2; glucosamine 6 phosphate isomerase; SB52; GlcN6P deaminase 2; Glucosamine 6 phosphate deaminase 2; Glucosamine 6 phosphate isomerase 2; Glucosamine 6 phosphate isomerase SB52; Glucosamine-6-phosphate isomerase SB52; GNP2; GNPDA 2; GNPI2_HUMAN; 4921523I18Rik; putative glucosamine-6-phosphate isomerase
    • Species :
    • Human
    • Mouse
    • Rhesus Macaque
    • Source :
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human GNPDA2-4679H Recombinant Human GNPDA2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human GNPDA2-5092H Recombinant Human GNPDA2 Protein, GST-tagged Wheat Germ GST
    Human GNPDA2-5842HCL Recombinant Human GNPDA2 293 Cell Lysate HEK293 N/A
    Mouse Gnpda2-3264M Recombinant Mouse Gnpda2 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Mouse GNPDA2-7051M Recombinant Mouse GNPDA2 Protein Mammalian Cell His
    Rhesus Macaque GNPDA2-1913R Recombinant Rhesus monkey GNPDA2 Protein, His-tagged Mammalian Cell His

    gnpda2 involved in several pathways and played different roles in them. We selected most pathways gnpda2 participated on our site, such as Amino sugar and nucleotide sugar metabolism, Metabolic pathways, N-acetylglucosamine degradation I, which may be useful for your reference. Also, other proteins which involved in the same pathway with gnpda2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Amino sugar and nucleotide sugar metabolism GNPDA1; GPR19; GMDS; GNPDA2; CHIA; HEXB; CHIT1; RENBP; CYB5R3; GALE
    Metabolic pathways LDHC; DGUOK; TYRP1B; ALG5; PLA2G4F; CYP27B1; PON2; PLCD3A; ACLYA; C1GALT1C1
    N-acetylglucosamine degradation I AMDHD2; GNPDA2; GNPDA1
    N-acetylglucosamine degradation II AMDHD2; GNPDA2; GNPDA1
    UDP-N-acetyl-D-galactosamine biosynthesis II GNPDA1; GNPDA2

    gnpda2 has several biochemical functions, for example, glucosamine-6-phosphate deaminase activity, hydrolase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by gnpda2 itself. We selected most functions gnpda2 had, and list some proteins which have the same functions with gnpda2. You can find most of the proteins on our site.

    Function Related Protein
    glucosamine-6-phosphate deaminase activity GNPDA1; GNPDA2
    hydrolase activity SMG6; NUDT22; DNASE2A; MMP23BB; SYNJ1; DAGLB; MRPL46; INPP5J; ADAMTS7; PNPLA7
    protein binding CPSF2; EME1; RP2; RGR; KL; SNX6; PDIA3; NPBWR2; PTGFRN; CLINT1

    gnpda2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with gnpda2 here. Most of them are supplied by our site. Hope this information will be useful for your research of gnpda2.

    TRIM27; AMDHD2

    Xi, B; Zhao, XY; et al. An obesity genetic risk score predicts risk of insulin resistance among Chinese children. ENDOCRINE 47:825-832(2014).
    Xi, B; Takeuchi, F; et al. Associations of genetic variants in/near body mass index-associated genes with type 2 diabetes: a systematic meta-analysis. CLINICAL ENDOCRINOLOGY 81:702-710(2014).

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