gp9 Protein, glycoprotein IX (platelet)


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Official Full Name glycoprotein IX (platelet)
Background This gene encodes a small membrane glycoprotein found on the surface of human platelets. It forms a 1-to-1 noncovalent complex with glycoprotein Ib, a platelet surface membrane glycoprotein complex that functions as a receptor for von Willebrand factor. The complete receptor complex includes noncovalent association of the alpha and beta subunits with the protein encoded by this gene and platelet glycoprotein V. Defects in this gene are a cause of Bernard-Soulier syndrome, also known as giant platelet disease. These patients have unusually large platelets and have a clinical bleeding tendency.
Synonyms GPIX; CD42a; GP9 platelet glycoprotein IX; GP-IX; glycoprotein 9; OTTHUMP00000217111
    • Species :
    • Human
    • Mouse
    • Rhesus Macaque
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human GP9-26632TH Recombinant Human GP9 Wheat Germ N/A
    Human GP9-5133H Recombinant Human GP9 Protein, GST-tagged Wheat Germ GST
    Human GP9-5820HCL Recombinant Human GP9 293 Cell Lysate HEK293 N/A
    Human GP9-7219H Recombinant Human GP9, His-tagged E.coli His
    Mouse GP9-7085M Recombinant Mouse GP9 Protein Mammalian Cell His
    Rhesus Macaque GP9-1925R Recombinant Rhesus monkey GP9 Protein, His-tagged Mammalian Cell His

    gp9 involved in several pathways and played different roles in them. We selected most pathways gp9 participated on our site, such as ECM-receptor interaction, Platelet activation, Hematopoietic cell lineage, which may be useful for your reference. Also, other proteins which involved in the same pathway with gp9 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    ECM-receptor interaction SV2C; COL5A1; ITGA1; TNR; LAMC2; GP1BA; COL4A2; SV2B; THBS2; GP5
    Platelet activation PIK3CG; ITGA2; ROCK2; PIK3R5; PIK3R3; PPP1R12A; MYLK2; PLA2G4F; RHOA; MAPK3
    Hematopoietic cell lineage IL1R1; IL7R; KITLG; CR2; THPO; CD22; CD1D; ITGA2; TNF; Il6ra

    gp9 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by gp9 itself. We selected most functions gp9 had, and list some proteins which have the same functions with gp9. You can find most of the proteins on our site.

    Function Related Protein
    protein binding INPP5A; PARP16; FST; MEAF6; IFI16; HFE; CDK2; WDR6; DOHH; ZCCHC12

    gp9 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with gp9 here. Most of them are supplied by our site. Hope this information will be useful for your research of gp9.

    SPRY2; GP1BA; HOXA1; GP5; APPBP2; CRK; Hoxa1; GP1BB

    Bragadottir, G; Birgisdottir, ER; et al. Clinical phenotype in heterozygote and biallelic Bernard-Soulier syndrome-A case control study. AMERICAN JOURNAL OF HEMATOLOGY 90:149-155(2015).
    Hassapis, KA; Stylianou, DC; et al. Architectural Insight into Inovirus-Associated Vectors (IAVs) and Development of IAV-Based Vaccines Inducing Humoral and Cellular Responses: Implications in HIV-1 Vaccines. VIRUSES-BASEL 6:5047-5076(2014).

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