|Official Full Name||glycoprotein IX (platelet)|
|Background||This gene encodes a small membrane glycoprotein found on the surface of human platelets. It forms a 1-to-1 noncovalent complex with glycoprotein Ib, a platelet surface membrane glycoprotein complex that functions as a receptor for von Willebrand factor. The complete receptor complex includes noncovalent association of the alpha and beta subunits with the protein encoded by this gene and platelet glycoprotein V. Defects in this gene are a cause of Bernard-Soulier syndrome, also known as giant platelet disease. These patients have unusually large platelets and have a clinical bleeding tendency.|
|Synonyms||GPIX; CD42a; GP9 platelet glycoprotein IX; GP-IX; glycoprotein 9; OTTHUMP00000217111|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
gp9 involved in several pathways and played different roles in them. We selected most pathways gp9 participated on our site, such as ECM-receptor interaction, Platelet activation, Hematopoietic cell lineage, which may be useful for your reference. Also, other proteins which involved in the same pathway with gp9 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|ECM-receptor interaction||SV2C; COL5A1; ITGA1; TNR; LAMC2; GP1BA; COL4A2; SV2B; THBS2; GP5|
|Platelet activation||PIK3CG; ITGA2; ROCK2; PIK3R5; PIK3R3; PPP1R12A; MYLK2; PLA2G4F; RHOA; MAPK3|
|Hematopoietic cell lineage||IL1R1; IL7R; KITLG; CR2; THPO; CD22; CD1D; ITGA2; TNF; Il6ra|
gp9 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by gp9 itself. We selected most functions gp9 had, and list some proteins which have the same functions with gp9. You can find most of the proteins on our site.
|protein binding||INPP5A; PARP16; FST; MEAF6; IFI16; HFE; CDK2; WDR6; DOHH; ZCCHC12|
gp9 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with gp9 here. Most of them are supplied by our site. Hope this information will be useful for your research of gp9.
SPRY2; GP1BA; HOXA1; GP5; APPBP2; CRK; Hoxa1; GP1BB