GPX3

  • Official Full Name

    glutathione peroxidase 3 (plasma)

  • Overview

    This gene product belongs to the glutathione peroxidase family, which functions in the detoxification of hydrogen;peroxide. It contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA;codon, which normally signals translation termination. The 3 UTR of Sec-containing genes have a common stem-loop;structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather;than as a stop signal.
  • Synonyms

    GPX3; glutathione peroxidase 3 (plasma); glutathione peroxidase 3; GPx-3; plasma glutathione peroxidase; extracellular glutathione peroxidase; GPx-P; GSHPx-3; GSHPx-P;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E. coli
  • E.coli
  • HEK293
  • HEK293F
  • Mammalian Cell
  • Flag
  • His
  • His (Fc)
  • Avi
  • His|T7
  • N
  • Tag Free
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human GPX3-8201H Recombinant Human GPX3 protein, His & T7-tagged E.coli His/T7
Human GPX3-1928H Recombinant Human Glutathione Peroxidase 3 (plasma), His-tagged His
Human GPX3-219H Recombinant Human GPX3 Mammalian Cell His
Human GPX3-29075TH Recombinant Human GPX3, FLAG-tagged HEK293 Flag
Human GPX3-29077TH Recombinant Human GPX3, His-tagged E.coli His
Human GPX3-2213H Recombinant Human GPX3 Protein, His-tagged E.coli N-His
Human GPX3-5310H Recombinant Human GPX3 Protein, His-tagged E.coli His
Human GPX3-3073H-B Recombinant Human GPX3 Protein Pre-coupled Magnetic Beads HEK293
Human GPX3-953H Recombinant Human GPX3 Protein, His-tagged HEK293F N-His
Human GPX3-3060H Recombinant Human GPX3 Protein (Gln21-Lys225), N-His tagged E.coli N-His
Human GPX3-3073H Recombinant Human GPX3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Gpx3-625M Recombinant Mouse Glutathione Peroxidase 3 (Plasma), FLAG-tagged HEK293 Flag
Mouse Gpx3-8202M Recombinant Mouse Gpx3 protein, His & T7-tagged E.coli His/T7
Mouse Gpx3-284M Recombinant Mouse Gpx3, FLAG-tagged HEK293 Flag
Mouse GPX3-7232M Recombinant Mouse GPX3 Protein Mammalian Cell His
Mouse Gpx3-01M Recombinant Mouse Gpx3 Protein, His-tagged E. coli His
Mouse GPX3-3903M Recombinant Mouse GPX3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse GPX3-3903M-B Recombinant Mouse GPX3 Protein Pre-coupled Magnetic Beads HEK293
Mouse Gpx3-22M Recombinant Mouse Gpx3 Protein Tag Free
Rat GPX3-2678R Recombinant Rat GPX3 Protein Mammalian Cell His
Rat GPX3-2332R Recombinant Rat GPX3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat GPX3-2332R-B Recombinant Rat GPX3 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish GPX3-7216Z Recombinant Zebrafish GPX3 Mammalian Cell His
Chicken GPX3-3974C Recombinant Chicken GPX3 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • GPX3 Related Articles
  • GPX3 Related Research Area

GPX3 involved in several pathways and played different roles in them. We selected most pathways GPX3 participated on our site, such as Glutathione metabolism, Arachidonic acid metabolism, Thyroid hormone synthesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with GPX3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Glutathione metabolismANPEPB;GGCTA;GSTK1;GSTA5;GSTP2;MGST1.1;ODC1;MGST1;GSTO2
Arachidonic acid metabolismCYP2J6;PLA2G2A;GGT1A;CYP2N13;PLA2G5;GGT1;PLA2G2D;PTGES3A;CYP2J2
Thyroid hormone synthesisTG;ATP1A3;GPX3;PLCB1;GSR;PRKACG;ITPR3;PAX8;ATP1A1

GPX3 has several biochemical functions, for example, glutathione peroxidase activity, protein binding, selenium binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GPX3 itself. We selected most functions GPX3 had, and list some proteins which have the same functions with GPX3. You can find most of the proteins on our site.

Function Related Protein
glutathione peroxidase activityGPX1A;MGST3;GSTT1;LTC4S;GSTZ1;GPX4B;GPX4;MGST1;GPX8
protein bindingFAM123A;SSX2;TBL3;CNNM3;ESD;ARL4A;ZNF133;CALD1;TMEM106C
selenium bindingSEPP1;DIO1;RPH3A;SELENBP2;GPX3;DIO2;SELT;SEP15;GPX1
transcription factor bindingTMEM173;KCTD1;HES2;GPX3;NFATC3;APBB1;CEBPG;DAXX;HDAC11

GPX3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GPX3 here. Most of them are supplied by our site. Hope this information will be useful for your research of GPX3.

UBQLN1; q7cgd4_yerpe; ohrA; trmFO; fadH; livM2; ftsY

Anugu, S; Petersson-Wolfe, CS; et al. Effect of vitamin E on the immune system of ewes during late pregnancy and lactation. SMALL RUMINANT RESEARCH 111:83-89(2013).
Lee, HJ; Do, JH; et al. Immunohistochemical evidence for the over-expression of Glutathione peroxidase 3 in clear cell type ovarian adenocarcinoma. MEDICAL ONCOLOGY 28:S522-S527(2011).
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