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GRIA4

  • Official Full Name

    Gria4 glutamate receptor, ionotropic, AMPA4 (alpha 4)

  • Synonyms

    GRIA4; glutamate receptor, ionotropic, AMPA4 (alpha 4); glutamate receptor 4; spike wave 1; glutamate receptor channel alpha 4; AMPA-selective glutamate receptor 4; glutamate receptor ionotropic, AMPA 4; GluA4; Glur4; spkw1; GluR-D; Glur-4; Gluralpha4;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • E. coli
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • C
  • His
  • GST
  • His (Fc)
  • Avi
  • N
  • SUMO
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human GRIA4-216H Recombinant Human GRIA4 Mammalian Cell His
Human GRIA4-3076H Recombinant Human GRIA4 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human GRIA4-954H Recombinant Human GRIA4 Protein, His&SUMO-tagged E.coli N-His&SUMO Arg385-Pro542
Human GRIA4-3214H Recombinant Human GRIA4 protein, His-tagged E.coli His Arg385~Pro542
Human GRIA4-5333H Recombinant Human GRIA4 Protein, GST-tagged Wheat Germ GST
Human GRIA4-5624HF Recombinant Full Length Human GRIA4 Protein, GST-tagged In Vitro Cell Free System GST 433 amino acids
Human GRIA4-3076H-B Recombinant Human GRIA4 Protein Pre-coupled Magnetic Beads HEK293
Human GRIA4-2770H Recombinant Human GRIA4 protein(731-800 aa), C-His-tagged E. coli C-His 731-800 aa
Chicken GRIA4-3797C Recombinant Chicken GRIA4 Mammalian Cell His
Chicken GRIA4-6767C Recombinant Chicken GRIA4 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • GRIA4 Related Articles

GRIA4 involved in several pathways and played different roles in them. We selected most pathways GRIA4 participated on our site, such as cAMP signaling pathway, Neuroactive ligand-receptor interaction, Circadian entrainment, which may be useful for your reference. Also, other proteins which involved in the same pathway with GRIA4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
cAMP signaling pathwayEP300;HCAR3;PDE4C;ARAP3;HTR1A;NFKB1;PTGER2;ATP1A2;RAP1A
Neuroactive ligand-receptor interactionTAAR14A;GABRB1;P2RX5;PTAFR;GRIK1;SSTR1;HCRTR2;PTGER1C;MC5RB
Circadian entrainmentGRIA4;ADCYAP1R1;GNG13;GNGT2;PER2;GRIN2A;KCNJ9;NOS1;GNG7
Retrograde endocannabinoid signalingGABRA6;GABRA2;PRKCG;GNB3;GNGT2;GNAI2;GABRR1;PTGS2;GNG5
Glutamatergic synapseADRBK2;GRM7;GNG5;PPP3R2;ITPR1;GRIN2A;PPP3CA;GNG4;PLD2
Dopaminergic synapsePPP1CC;PPP2CA;PPP1CB;GNG10;CAMK2G;CLOCK;PRKCB;PLCB3;ARRB2
Nicotine addictionGRIN2C;GABRG3;GRIN2A;GABRD;SLC17A6;GABRB1;GABRP;GABRR3;GRIA1

GRIA4 has several biochemical functions, for example, AMPA glutamate receptor activity, extracellular-glutamate-gated ion channel activity, ionotropic glutamate receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GRIA4 itself. We selected most functions GRIA4 had, and list some proteins which have the same functions with GRIA4. You can find most of the proteins on our site.

Function Related Protein
AMPA glutamate receptor activityGRIA4A;GRIA3;GRIA1B;GRIA4;GRIA1A;GRIA2;GRIA2B;GRIA3B;GRIA2A
extracellular-glutamate-gated ion channel activityGRID1;GRIN1A;GRIN2A;GRIA2B;GRIA1;GRIN3B;GRIN2BB;GRIK1;GRIN2D
ionotropic glutamate receptor activityGRIA2A;GRIN2A;GRIK5;GRIA4A;GRIN1B;GRIN1A;GRIA2;GRIA1B;GRIK3

GRIA4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GRIA4 here. Most of them are supplied by our site. Hope this information will be useful for your research of GRIA4.

PTBP3; PRKACA; CAMK2A

Panzer, JA; Gleichman, AJ; et al. Glutamatergic autoencephalitides: an emerging field. JOURNAL OF NEURAL TRANSMISSION 121:957-968(2014).
Trippe, J; Steinke, K; et al. Autoantibodies to Glutamate Receptor Antigens in Multiple Sclerosis and Rasmussen's Encephalitis. NEUROIMMUNOMODULATION 21:189-194(2014).
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