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GRM1

  • Official Full Name

    Grm1 glutamate receptor, metabotropic 1

  • Synonyms

    GRM1; glutamate receptor, metabotropic 1; metabotropic glutamate receptor 1; G protein coupled receptor, family C, group 1, member A; G protein-coupled receptor, family C, group 1, member A; rcw; wobl; Gprc1a; mGluR1; nmf373; Gm10828; 4930455H15Rik; MGC90744; ENSMUSG00000075319;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • Zebrafish
  • E. coli
  • E.coli
  • HEK293
  • Mammalian Cell
  • Wheat Germ
  • C
  • His
  • GST
  • His (Fc)
  • Avi
  • Flag
  • His|T7
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human GRM1-29607TH Recombinant Human GRM1 protein, GST-tagged Wheat Germ GST
Human GRM1-1355H Recombinant Human GRM1 protein, His & T7-tagged E.coli His/T7 Ser165~Glu592 (Accession# Q13255)
Human GRM1-5737HCL Recombinant Human GRM1 293 Cell Lysate HEK293 N/A
Human GRM1-2548H Recombinant Human GRM1 Protein (Ser165-Glu592), N-His tagged E.coli N-His Ser165-Glu592
Human GRM1-1139HFL Recombinant Human GRM1 protein, His&Flag-tagged HEK293 His&Flag
Human GRM1-2851H Recombinant Human GRM1 protein(881-960 aa), C-His-tagged E. coli C-His 881-960 aa
Mouse GRM1-7284M Recombinant Mouse GRM1 Protein Mammalian Cell His
Mouse GRM1-3939M Recombinant Mouse GRM1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse GRM1-3939M-B Recombinant Mouse GRM1 Protein Pre-coupled Magnetic Beads HEK293
Rat GRM1-2713R Recombinant Rat GRM1 Protein Mammalian Cell His
Rat GRM1-2367R Recombinant Rat GRM1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat GRM1-2367R-B Recombinant Rat GRM1 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque GRM1-1976R Recombinant Rhesus monkey GRM1 Protein, His-tagged Mammalian Cell His
Rhesus Macaque GRM1-1797R-B Recombinant Rhesus Macaque GRM1 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque GRM1-1797R Recombinant Rhesus Macaque GRM1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish GRM1-8498Z Recombinant Zebrafish GRM1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • GRM1 Related Articles
  • GRM1 Related Gene Family

GRM1 involved in several pathways and played different roles in them. We selected most pathways GRM1 participated on our site, such as Calcium signaling pathway, FoxO signaling pathway, Phospholipase D signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with GRM1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Calcium signaling pathwayADCY2B;ADRA1BB;GRIN2A;AGTR1;DRD1B;CALML3;GNAS;HRH1;PLCB1
FoxO signaling pathwayG6PC3;NLK1;INS;INSRA;G6PCA.1;G6PC2;HRASA;SMAD3;GABARAPA
Phospholipase D signaling pathwayINSR;KRAS;DGKD;RRAS2;AGTR1A;MAPK3;AKT2;INS1;CYTH4
Neuroactive ligand-receptor interactionGRIA2A;HTR1AA;PTGIR;GABRP;LHB;HTR1E;DRD1A;TSHB;MC5RB
Gap junctionGRB2;MAPK3;TUBAL3;GUCY1A3;PLCB4;TUBA3B;ADCY1A;Adcy4;PRKCBB
Long-term potentiationMAP2K1;CALM1;PPP3CB;CALML5;PLCB2;PPP1CB;PPP3R2;RPS6KA6;PPP3CA
Retrograde endocannabinoid signalingGRIA3;GRM1;GNG7;ITPR3;SLC17A8;RIMS1;PRKCA;GABRG2;ABHD6
Glutamatergic synapsePLCB1;GNB2;GLS2;PLCB3;ITPR3;SLC38A1;PLD2;GRM5;GNG4
Long-term depressionPPP2R1A;GNAZ;PRKCG;LYN;MAP2K2;CRH;GNAS;GUCY1B3;PRKG2
Estrogen signaling pathwayPIK3R5;ATF4;PRKACG;KCNJ5;CALML3;HSPA8;NRAS;HSP90B1;HSP90AB1

GRM1 has several biochemical functions, for example, G-protein coupled receptor activity, glutamate receptor activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GRM1 itself. We selected most functions GRM1 had, and list some proteins which have the same functions with GRM1. You can find most of the proteins on our site.

Function Related Protein
G-protein coupled receptor activityTAAR8A;LPAR2B;OR2C1;OR4D6;CXCR1;OPN5;OXTRL;SMO;OLFR688
glutamate receptor activityGRIA1;GRIK5;GRM7;GRM1;GRM6;GRM4;GRM8;GRM3;GRM2
protein bindingTRIM44;LILRB4;KLHL41;PIP4K2B;EHD3;EDN1;MATN3;FAM151B;ADH1A

GRM1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GRM1 here. Most of them are supplied by our site. Hope this information will be useful for your research of GRM1.

KPNA1; KPNA3

Dahm, L; Ott, C; et al. Seroprevalence of Autoantibodies against Brain Antigens in Health and Disease. ANNALS OF NEUROLOGY 76:82-94(2014).
Masuda, M; Morimoto, T; et al. Measurement of soluble Fc gamma receptor type IIIa derived from macrophages in plasma: increase in patients with rheumatoid arthritis. CLINICAL AND EXPERIMENTAL IMMUNOLOGY 132:477-484(2003).
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