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GTF3A

Official Full Name

general transcription factor IIIA
Overview

The product of this gene is a zinc finger protein with nine Cis[2]-His[2] zinc finger domains. It functions as an RNA polymerase III transcription factor to induce transcription of the 5S rRNA genes. The protein binds to a 50 bp internal promoter in the 5S genes called the internal control region (ICR), and nucleates formation of a stable preinitiation complex. This complex recruits the TFIIIC and TFIIIB transcription factors and RNA polymerase III to form the complete transcription complex. The protein is thought to be translated using a non-AUG translation initiation site in mammals based on sequence analysis, protein homology, and the size of the purified protein. [provided by RefSeq, Jul 2008]
Synonyms

GTF3A; general transcription factor IIIA; AP2; TFIIIA; transcription factor IIIA;

Type

Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Chicken
Human
Mouse
Rat

Source

E.coli
HEK293
Mammalian Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi
His|T7
N

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	GTF3A-4461H	Recombinant Human GTF3A Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	GTF3A-1057H	Recombinant Human GTF3A protein, His & T7-tagged	E.coli	His/T7	Val71~Gly365 (Accession # Q92664)	Inquiry
Mouse	GTF3A-7366M	Recombinant Mouse GTF3A Protein	Mammalian Cell	His		Inquiry
Mouse	Gtf3a-1605M	Recombinant Mouse Gtf3a Protein, His&GST-tagged	E.coli	N-His&GST	Gly166-Cys364	Inquiry
Mouse	GTF3A-3996M	Recombinant Mouse GTF3A Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	GTF3A-3996M-B	Recombinant Mouse GTF3A Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rat	GTF3A-2746R	Recombinant Rat GTF3A Protein	Mammalian Cell	His		Inquiry
Rat	GTF3A-2400R	Recombinant Rat GTF3A Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rat	Gtf3a-1681R	Recombinant Rat Gtf3a protein, His & T7-tagged	E.coli	His/T7	Val69~His363 (Accession # Q8VHT8)	Inquiry
Rat	GTF3A-2400R-B	Recombinant Rat GTF3A Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Chicken	GTF3A-3806C	Recombinant Chicken GTF3A	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein

GTF3A involved in several pathways and played different roles in them. We selected most pathways GTF3A participated on our site, such as Gene Expression, RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription, RNA Polymerase III Transcription, which may be useful for your reference. Also, other proteins which involved in the same pathway with GTF3A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Gene Expression	ZNF71;ZNF2;RNPC3;TBX5;TET3;ZNF563;RRP8;ZNF621;NR2C2AP
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription	GATAD2B;CHD4A;SNAPC1A;POLR3GLA;GTF3C2;CBX3A;BRF1;NFIA;ZNF143
RNA Polymerase III Transcription	ZNF143;SNAPC5;SNAPC2;NFIB;ZNF143A;GTF3C3;SNAPC1;BRF1;BRF2
RNA Polymerase III Transcription Initiation	SNAPC5;SNAPC2;BRF1;ZFP143;SNAPC4;SNAPC1B;GTF3AB;POU2F1B;GTF3C3
RNA Polymerase III Transcription Initiation From Type 1 Promoter	BRF1;GTF3C4;GTF3C3;BRF1B;GTF3AB;GTF3A;POLR3GLA;GTF3C2;GTF3C5

GTF3A has several biochemical functions, for example, DNA binding, RNA binding, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GTF3A itself. We selected most functions GTF3A had, and list some proteins which have the same functions with GTF3A. You can find most of the proteins on our site.

Function	Related Protein
DNA binding	PPARA;CIC;ADNPA;TCF3;BRCA1;HEMK1;LEMD3;LMX1BB;PARP1
RNA binding	LIN28A;PTBP1B;DOM3Z;PABPC1L;TRIM32;HNRNPD;MOV10B.1;TIMM50;RPL7A
metal ion binding	TATDN3;RXRAB;AARSD1;PDE1C;KDM4D;SNAI1A;KLK1B4;NR1H5;TIMP4
nucleic acid binding	KLF11B;ZFP516;ZFP91;ZFP667;GPATCH1;EWSR1A;ZNF728;SRSF6A;NPM2A
transcription factor activity, sequence-specific DNA binding	WNT5A;ZNF287;MAFA;POU5F1;FOXB1A;SRF;MECP2;FOXP1A;HOXD3

GTF3A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GTF3A here. Most of them are supplied by our site. Hope this information will be useful for your research of GTF3A.