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GUCY2F

Official Full Name

guanylate cyclase 2F, retinal
Overview

The protein encoded by this gene is a guanylyl cyclase found predominantly in photoreceptors in the retina. The encoded protein is thought to be involved in resynthesis of cGMP after light activation of the visual signal transduction cascade, allowing a return to the dark state. This protein is a single-pass type I membrane protein. Defects in this gene may be a cause of X-linked retinitis pigmentosa.
Synonyms

GUCY2F; guanylate cyclase 2F, retinal; retinal guanylyl cyclase 2; CYGF; GC F; guanylate cyclase 2D like; membrane (retina specific); GUC2DL; RetGC 2; ROS GC2; guanylate cyclase F; rod outer segment membrane guanylate cyclase 2; guanylate cyclase 2D-like,;

Type

Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Human
Rat
Zebrafish

Source

E.coli
HEK293
Mammalian Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	GUCY2F-4494H	Recombinant Human GUCY2F Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	GUCY2F-0406H	Recombinant Human GUCY2F protein, His-tagged	E.coli	His	71-398 aa	$319 / 25ug
Rat	GUCY2F-2759R	Recombinant Rat GUCY2F Protein	Mammalian Cell	His		Inquiry
Rat	GUCY2F-2413R-B	Recombinant Rat GUCY2F Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rat	GUCY2F-2413R	Recombinant Rat GUCY2F Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Zebrafish	GUCY2F-9369Z	Recombinant Zebrafish GUCY2F	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein

GUCY2F involved in several pathways and played different roles in them. We selected most pathways GUCY2F participated on our site, such as Purine metabolism, Phototransduction, which may be useful for your reference. Also, other proteins which involved in the same pathway with GUCY2F were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Purine metabolism	POLR3B;IMPDH1B;NT5C1AA;PDE5AB;ZNRD1;GART;POLD1;PDE6C;PRUNE
Phototransduction	GRK1B;GNGT1;GUCA1D;GRK1A;CALM3A;GRK1;CALM1;GNAT1;GUCY2F

GUCY2F has several biochemical functions, for example, ATP binding, NOT adenylate cyclase activity, guanylate cyclase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GUCY2F itself. We selected most functions GUCY2F had, and list some proteins which have the same functions with GUCY2F. You can find most of the proteins on our site.

Function	Related Protein
ATP binding	NIM1K;OASL;PSKH2;DHX9;CHD2;MYLK;KIF21A;UBE2G1A;TOP2B
NOT adenylate cyclase activity	GUCY2C;GC3;NPR2;GUCY1A3;NPR3;GC2;NPR1;NPR1A;GUCY1B3
guanylate cyclase activity	NPR1A;GUCY2F;NPR2;GC3;GUCY1A3;GUCY2C;NPR1;GC2;GUCY1B3
lyase activity	ETNPPL;CAR3;GAD1B;ENO1A;GLDC;Car2;ALDOCA;CTHL;MVDA
nucleotide binding	RNPC3;TUBA8L3;MAP4K6;RBM14;CKBA;PANK1A;ARL8;CRY1;PRAC
phosphorus-oxygen lyase activity	CD38;BST1;ADCY1A;GUCY2E;NPR1A;GC2;GUCY2F;ADCY2B;GC3
protein kinase activity	PDK3;RPS6KB1;MAP3K5;NEK5;BSK146;CSNK2A2A;NTRK2B;IRAK4;PKN1B

GUCY2F has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GUCY2F here. Most of them are supplied by our site. Hope this information will be useful for your research of GUCY2F.