|Official Full Name||hypocretin (orexin) receptor 2|
|Background||The protein encoded by this gene is a G-protein coupled receptor involved in the regulation of feeding behavior. The encoded protein binds the hypothalamic neuropeptides orexin A and orexin B. A related gene (HCRTR1) encodes a G-protein coupled receptor that selectively binds orexin A.|
|Synonyms||HCRTR2; hypocretin (orexin) receptor 2; orexin receptor type 2; OX2R; Hypocretin receptor 2; Hypocretin receptor type 2; Orexin receptor 2; Ox-2-R; Ox2-R; OX2R_HUMAN; OTTHUMP00000017762|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
hcrtr2 involved in several pathways and played different roles in them. We selected most pathways hcrtr2 participated on our site, such as Neuroactive ligand-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with hcrtr2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Neuroactive ligand-receptor interaction||CHRNB3A; TACR1B; GRIK2; GALR3; CCKAR; Chrng; VIPR1; CHRNA2A; PTGER1B; GHRHR|
hcrtr2 has several biochemical functions, for example, neuropeptide receptor activity, orexin receptor activity, peptide binding. Some of the functions are cooperated with other proteins, some of the functions could acted by hcrtr2 itself. We selected most functions hcrtr2 had, and list some proteins which have the same functions with hcrtr2. You can find most of the proteins on our site.
|neuropeptide receptor activity||HCRTR1; NPFFR1L1; NPFFR1L2; KISS1RA; SORCS3; NPFFR2.1; KISS1RB; NMUR1; SORCS2; NPBWR2|
|orexin receptor activity||HCRTR1; HCRTR2|
|peptide binding||MAS1; ANG; ANPEP; NPFFR2.1; AVPR1B; ANPEPA; NPFFR1; AVPR2L; PPYR1; RPS6KB2|
|peptide hormone binding||ACVR1; GHRHR; NPR2; EDNRB; PTH1RB; HCRTR2; AVPR1A; GALR3; MC3R; MAS1|
hcrtr2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with hcrtr2 here. Most of them are supplied by our site. Hope this information will be useful for your research of hcrtr2.