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Official Full Name hypocretin (orexin) receptor 2
Background The protein encoded by this gene is a G-protein coupled receptor involved in the regulation of feeding behavior. The encoded protein binds the hypothalamic neuropeptides orexin A and orexin B. A related gene (HCRTR1) encodes a G-protein coupled receptor that selectively binds orexin A.
Synonyms HCRTR2; hypocretin (orexin) receptor 2; orexin receptor type 2; OX2R; Hypocretin receptor 2; Hypocretin receptor type 2; Orexin receptor 2; Ox-2-R; Ox2-R; OX2R_HUMAN; OTTHUMP00000017762
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Zebrafish
    • Source :
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human HCRTR2-4636H Recombinant Human HCRTR2 Protein, GST-tagged Wheat Germ GST
    Human HCRTR2-775HCL Recombinant Human HCRTR2 cell lysate N/A
    Mouse HCRTR2-7524M Recombinant Mouse HCRTR2 Protein Mammalian Cell His
    Rat HCRTR2-2812R Recombinant Rat HCRTR2 Protein Mammalian Cell His
    Chicken HCRTR2-2188C Recombinant Chicken HCRTR2 Mammalian Cell His
    Zebrafish HCRTR2-4905Z Recombinant Zebrafish HCRTR2 Mammalian Cell His
    Kit-1341 HCRTR2 CHO-K1 β-Arrestin GPCR Assay Kit N/A
    Kit-1342 HCRTR2 Total GPCR Internalization Assay Kit N/A

    hcrtr2 involved in several pathways and played different roles in them. We selected most pathways hcrtr2 participated on our site, such as Neuroactive ligand-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with hcrtr2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Neuroactive ligand-receptor interaction CHRNB3A; TACR1B; GRIK2; GALR3; CCKAR; Chrng; VIPR1; CHRNA2A; PTGER1B; GHRHR

    hcrtr2 has several biochemical functions, for example, neuropeptide receptor activity, orexin receptor activity, peptide binding. Some of the functions are cooperated with other proteins, some of the functions could acted by hcrtr2 itself. We selected most functions hcrtr2 had, and list some proteins which have the same functions with hcrtr2. You can find most of the proteins on our site.

    Function Related Protein
    neuropeptide receptor activity HCRTR1; NPFFR1L1; NPFFR1L2; KISS1RA; SORCS3; NPFFR2.1; KISS1RB; NMUR1; SORCS2; NPBWR2
    orexin receptor activity HCRTR1; HCRTR2
    peptide binding MAS1; ANG; ANPEP; NPFFR2.1; AVPR1B; ANPEPA; NPFFR1; AVPR2L; PPYR1; RPS6KB2
    peptide hormone binding ACVR1; GHRHR; NPR2; EDNRB; PTH1RB; HCRTR2; AVPR1A; GALR3; MC3R; MAS1

    hcrtr2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with hcrtr2 here. Most of them are supplied by our site. Hope this information will be useful for your research of hcrtr2.

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