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Official Full Name histamine receptor H3
Background Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. This gene encodes one of the histamine receptors (H3) which belongs to the family 1 of G protein-coupled receptors. It is an integral membrane protein and can regulate neurotransmitter release. This receptor can also increase voltage-dependent calcium current in smooth muscles and innervates the blood vessels and the heart in cardiovascular system.
Synonyms HRH3; histamine receptor H3; histamine H3 receptor; GPCR97; H3R; G protein-coupled receptor 97; G-protein coupled receptor 97; HH3R
    • Species :
    • Human
    • Mouse
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human HRH3-5037H Recombinant Human HRH3 Protein, GST-tagged Wheat Germ GST
    Human HRH3-702H Recombinant Human HRH3 Mammalian Cell His
    Mouse HRH3-7850M Recombinant Mouse HRH3 Protein Mammalian Cell His
    Rhesus Macaque HRH3-2144R Recombinant Rhesus monkey HRH3 Protein, His-tagged Mammalian Cell His
    Zebrafish HRH3-3136Z Recombinant Zebrafish HRH3 Mammalian Cell His
    Kit-0970 TR-FRET PPAR gamma Competitive Binding Assay Kit, goat N/A
    Kit-1075 Chitotriosidase Activity Assay Kit (Fluorometric) N/A
    Kit-1346 cAMP HRH3 CHO-K1 GPCR Assay Kit N/A
    Kit-1347 HRH3 CHO-K1 β-Arrestin GPCR Assay Kit N/A

    HRH3 involved in several pathways and played different roles in them. We selected most pathways HRH3 participated on our site, such as Amine ligand-binding receptors, Class A/1 (Rhodopsin-like receptors), G alpha (i) signalling events, which may be useful for your reference. Also, other proteins which involved in the same pathway with HRH3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Amine ligand-binding receptors DRD3; DRD4; CHRM4; ADRa1A; DRD5; CHRM2; ADRB3; TAAR1; ADRB1; CHRM5
    Class A/1 (Rhodopsin-like receptors) S1PR3; NMBA; HRH3; RGS1; GPR17; NMB; OXGR1A.2; ADORA3; CCBP2; FPR-RS4
    G alpha (i) signalling events DRD2; NMUR1; AMCF-II; ADORA1; TAS2R7; FPR-RS6; RGS20; NMS; SSTR2; APPB
    GPCR downstream signaling OXGR1A.2; SSTR2; MCF2L; ADM2; PENKB; OPN5; RAMP1; CNR1; APLNR; OPN4
    GPCR ligand binding DRD5; RAMP2; CXCL11.8; PENKB; UTS2D; CCR3; KEL; PTHLH; QRFP; CNR2
    GPCRs, Class A Rhodopsin-like SSTR5; ADORA1; GPR63; OPN1MW2; CMKLR1; CCR9; CCR8; SSTR4; CCR7; FPR-RS4
    Histamine receptors HRH3
    Monoamine Transport UNC13B; DBH; TPH2; TGFB1I1; SCAMP2; SYN1; FBXO32; HRH3

    HRH3 has several biochemical functions, for example, histamine binding, histamine receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by HRH3 itself. We selected most functions HRH3 had, and list some proteins which have the same functions with HRH3. You can find most of the proteins on our site.

    Function Related Protein
    histamine binding HRH3; HRH1; HRH4
    histamine receptor activity HTR6; HRH1; HRH2; HRH4; HRH3

    HRH3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HRH3 here. Most of them are supplied by our site. Hope this information will be useful for your research of HRH3.

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