hrh4

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hrh4

Official Full Name histamine receptor H4
Background Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by a family of histamine receptors, which are a subset of the G-protein coupled receptor superfamily. This gene encodes a histamine receptor that is predominantly expressed in haematopoietic cells. The protein is thought to play a role in inflammation and allergy reponses. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]
Synonyms HRH4; histamine receptor H4; H4; H4R; BG26; HH4R; AXOR35; GPRv53; GPCR105; histamine H4 receptor; SP9144; pfi-013; G-protein coupled receptor 105;
    • Species :
    • Cynomolgus Monkey
    • Human
    • Mouse
    • Rat
    • Source :
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human HRH4-5038H Recombinant Human HRH4 Protein, GST-tagged Wheat Germ GST
    Mouse HRH4-7851M Recombinant Mouse HRH4 Protein Mammalian Cell His
    Rat HRH4-2913R Recombinant Rat HRH4 Protein Mammalian Cell His
    Cynomolgus Monkey HRH4-596C Recombinant Cynomolgus HRH4 Protein, His-tagged Mammalian Cell His
    Kit-0884 Midi Protein Expression Kit N/A
    Kit-1348 HRH4 U2OS β-Arrestin GPCR Assay Kit N/A

    hrh4 involved in several pathways and played different roles in them. We selected most pathways hrh4 participated on our site, such as Neuroactive ligand-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with hrh4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Neuroactive ligand-receptor interaction PRLR; NPFFR2; P2RX4B; PTGER2; MC5RA; MC1R; P2RY14; GABRB1; GLRA2; GRIK2

    hrh4 has several biochemical functions, for example, histamine binding, histamine receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by hrh4 itself. We selected most functions hrh4 had, and list some proteins which have the same functions with hrh4. You can find most of the proteins on our site.

    Function Related Protein
    histamine binding HRH3; HRH1; HRH4
    histamine receptor activity HRH2; HRH1; HRH3; HRH4; HTR6

    hrh4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with hrh4 here. Most of them are supplied by our site. Hope this information will be useful for your research of hrh4.

    Schneider, EH; Neumann, D; et al. Modulation of behavior by the histaminergic system: Lessons from HDC-, H3R- and H4R-deficient mice. NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS 47:101-121(2014).
    Yu, B; Shao, Y; et al. Copy number variations of the human histamine H4 receptor gene are associated with systemic lupus erythematosus. BRITISH JOURNAL OF DERMATOLOGY 163:935-940(2010).

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