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Official Full Name hydroxysteroid (17-beta) dehydrogenase 8
Background Keratins (cytokeratins) are intermediate filament proteins that are mainly expressed in epithelial cells. Keratin heterodimers composed of an acidic keratin (or type I keratin, keratins 9 to 23) and a basic keratin (or type II keratin, keratins 1 to 8) as
Synonyms HSD17B8; hydroxysteroid (17-beta) dehydrogenase 8; FabG (beta ketoacyl [acyl carrier protein] reductase, E coli) like (E. coli) , FABGL; estradiol 17-beta-dehydrogenase 8; D6S2245E; H2 KE6; HKE6; KE6; RING2; SDR30C1; short chain dehydrogenase/reductase fa
    • Species :
    • Cynomolgus Monkey
    • Human
    • Rat
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human HSD17B8-13964H Recombinant Human HSD17B8, GST-tagged E.coli GST
    Human HSD17B8-29342TH Recombinant Human HSD17B8, His-tagged E.coli His
    Human HSD17B8-3499H Recombinant Human HSD17B8, His-tagged E.coli His
    Human HSD17B8-5076H Recombinant Human HSD17B8 Protein, GST-tagged Wheat Germ GST
    Human HSD17B8-5371HCL Recombinant Human HSD17B8 293 Cell Lysate HEK293 N/A
    Rat HSD17B8-2931R Recombinant Rat HSD17B8 Protein Mammalian Cell His
    Cynomolgus Monkey HSD17B8-603C Recombinant Cynomolgus HSD17B8 Protein, His-tagged Mammalian Cell His
    Rhesus Macaque HSD17B8-2157R Recombinant Rhesus monkey HSD17B8 Protein, His-tagged Mammalian Cell His
    Zebrafish HSD17B8-1393Z Recombinant Zebrafish HSD17B8 Mammalian Cell His

    hsd17b8 involved in several pathways and played different roles in them. We selected most pathways hsd17b8 participated on our site, such as Steroid hormone biosynthesis, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with hsd17b8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Steroid hormone biosynthesis HSD17B3; UGT5G1; HSD17B12A; UGT2A1; CYP7B1; HSD17B1; CYP2C37; SRD5A3; SULT2B1; SRD5A2B
    Metabolic pathways TREH; SHMT1; B3GNT5A; SRM; UQCRQ; ATP5J2; CKBB; ATP6V1C2; AOX4; EXTL1

    hsd17b8 has several biochemical functions, for example, 3-hydroxyacyl-CoA dehydrogenase activity, estradiol 17-beta-dehydrogenase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by hsd17b8 itself. We selected most functions hsd17b8 had, and list some proteins which have the same functions with hsd17b8. You can find most of the proteins on our site.

    Function Related Protein
    3-hydroxyacyl-CoA dehydrogenase activity HADHA; HSD17B10; HADHB; H2-KE6; HADHAB; HSD17B4; HADHAA; HSD17B8; EHHADH; HADH
    estradiol 17-beta-dehydrogenase activity AKR1C6; HSD17B12A; AKR1B15; RDH8B; HSD17B8; HSD17B2; HSD17B12; HSD17B11; RDH8A; HSD17B14
    protein binding SPN; TERF2IP; OTX2; FBXL14; GTF2H2; ESRRA; LGALS14; KLRB1F; PPID; FAM134B
    testosterone dehydrogenase (NAD+) activity HSD17B8; HSD17B6; AKR1C3; HSD17B2; HSD17B1; DHRS9; H2-KE6

    hsd17b8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with hsd17b8 here. Most of them are supplied by our site. Hope this information will be useful for your research of hsd17b8.


    Yang, FQ; Priester, S; et al. Castration inhibits biliary proliferation induced by bile duct obstruction: novel role for the autocrine trophic effect of testosterone. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY 301:G981-G991(2011).
    Motohara, K; Tashiro, H; et al. Immunohistochemical analysis of 17 beta-hydroxysteroid dehydrogenase isozymes in human ovarian surface epithelium and epithelial ovarian carcinoma. MEDICAL MOLECULAR MORPHOLOGY 43:197-203(2010).

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