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Official Full Name interferon, alpha 14
Background Interferon alpha-14 is a protein that in humans is encoded by the IFNA14 gene.
Synonyms IFNA14; interferon, alpha 14; interferon alpha-14; IFN alphaH; LEIF2H; Interferon alpha 14; Interferon alpha H; Interferon lambda2H; LeIF H; LeIFH; IFN-alpha-14; interferon alpha-H; interferon lambda-2-H; IFN-alphaH
    • Species :
    • Cynomolgus Monkey
    • Human
    • Mouse
    • Source :
    • E.coli
    • HEK293
    • Human Cell
    • Yeast
    • Tag :
    • Fc
    • His
    • SUMO
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human IFNA14-1253H Recombinant Human IFNA14 Protein, His-SUMO-tagged E.coli His/SUMO
    Human IFNA14-1423H Recombinant Human IFNA14 Protein (24-189 aa), His-tagged Yeast His
    Human IFNA14-146H Recombinant Human Interferon, Alpha 14, His-tagged E.coli His
    Human IFNA14-15840H Recombinant Human IFNA14, His-tagged E.coli His
    Human IFNA14-43H Recombinant Human Interferon, Alpha 14 E.coli N/A
    Mouse Ifna14-121M Recombinant Mouse Ifna14, Fc-tagged Human Cell Fc
    Mouse IFNA14-224M Recombinant Mouse IFNA14, His-tagged Human Cell His
    Mouse Ifna14-60M Recombinant Mouse Ifna14, Fc tagged Human Cell Fc
    Mouse Ifna14-61M Recombinant Mouse Ifna14, His tagged Human Cell His
    Mouse IFNA14-902MCL Recombinant Mouse IFNA14 cell lysate Human Cell N/A
    Mouse Ifng14-121M Recombinant Mouse Ifng14 protein, Fc-tagged HEK293 Fc
    Cynomolgus Monkey IFNA14-188C Recombinant Cynomolgus IFNA14, His-tagged Yeast His

    ifna14 involved in several pathways and played different roles in them. We selected most pathways ifna14 participated on our site, such as Cytokine-cytokine receptor interaction, Regulation of autophagy, PIK-Akt signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with ifna14 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cytokine-cytokine receptor interaction PF4V1; TNFRSF10B; IL10; PRP2; CCL19; IL23R; GM13305; Ifna11; CXCR4B; CXCL9
    Regulation of autophagy ATG4A; IFNA17; IFNA7; ATG14; IFNA21; IFNA2; GABARAP; ATG4D; INS1; GABARAPA
    PIK-Akt signaling pathway IFNA2; PRKCA; G6PC2; LAMB1; NRAS; FGF20; PPP2CA; FGF5; PHLPP1; PRLR
    Toll-like receptor signaling pathway IFNA2; MAP2K2A; MYD88; CD40; CCL3L3; MAP2K1; IFNA13; TLR9; RIPK1; IFNPHI1
    RIG-I-like receptor signaling pathway IL8L2; TRAF2; MAPK10; DDX3; IFNE; CXCL8B.3; MAPK14A; DHX58; TRAF3; FADD
    Cytosolic DNA-sensing pathway IFNA4; IFNA1; IFNA5; IKBKE; IFNA7; IFN-a; POLR3H; IFNPHI3; RIPK3; IRF7
    Jak-STAT signaling pathway IL23; PTPN2; IFNA3; PRL; BCL2A; CRFB4; IL21R; HRASB; STAM2; IFNA1
    Natural killer cell mediated cytotoxicity MAPK3; IFNA21; IFNGR2; KIR2DL3; IFNA13; PRKCA; SHC1; GM-CSF; SOS1; NFATC2
    Tuberculosis Il23a; Il12b; MAPK11; MAPK13; CLEC4E; CYCS; SPHK1; IFNGR1; CAMK2A; ARHGEF12; IFNA2
    Hepatitis C GSK3B; GRB2; OCLN; DDX58; MAPK9; IFNAR2; IRF3; TRAF2; OAS1; IFNA1
    Hepatitis B FASLG; IFNA6; IFNA12; Ifna15; MAP2K2; CREB3L3; CCNE1; CASP10; BAD; TNF
    Influenza A PIK3R1; BMA1; HLA-DPA1; HLA-DQA2; MAP2K2; TBK1; OAS1A; IL6; PLG; HNRNPUL1
    Herpes simplex infection TAF9B; STAT1A; IFNAR2; FB06F03; HLA-B; NXF1; PVRL1B; TBP; IKBKE; EEF1DA
    ne thyroid disease HLA-DMB; IFNA6; CD80; IL5; HLA-DOB; IFNA16; TPO; IL4; IFNA1; HLA-DQA2

    ifna14 has several biochemical functions, for example, cytokine activity, cytokine receptor binding, type I interferon receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ifna14 itself. We selected most functions ifna14 had, and list some proteins which have the same functions with ifna14. You can find most of the proteins on our site.

    Function Related Protein
    cytokine activity IL36RN; HMGB1; IFNA17; BMP8B; IL36G; IFNA6; LFT1; TNFSF15; IL9; GDF6B
    cytokine receptor binding IL17A/F2; IFNA3; IFNPHI1; IL15; IFNPHI2; IL17F; IFN-a; IL15L; IFNA14; IL17C
    type I interferon receptor binding IFNA17; Ifnz; IFNA21; IFNPHI3; IFNB; IFNA6; GM13289; IFNA1; Gm13290; IFNA3

    ifna14 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ifna14 here. Most of them are supplied by our site. Hope this information will be useful for your research of ifna14.

    Miterski, B; Jaeckel, S; et al. The interferon gene cluster: a candidate region for MS predisposition?. GENES AND IMMUNITY 1:37-44(1999).

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