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Official Full Name interferon, alpha 21
Background This gene is a member of the alpha interferon gene cluster on the short arm of chromosome 9. Interferons are cytokines produced in response to viral infection that mediate the immune response and interfere with viral replication. The encoded protein is a type I interferon and may play a specific role in the antiviral response to rubella virus.
Synonyms IFNA21; interferon, alpha 21; interferon alpha-21; IFN alphaI; leukocyte interferon protein; Interferon alpha F; LeIF F; MGC126687; MGC126689; IFN-alpha-21; interferon alpha-F; leIF-F; IFN-alphaI
    • Species :
    • Human
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Spf Chicken Eggs
    • Yeast
    • Tag :
    • His
    • GST
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human IFNA21-140H Recombinant Human Interferon, Alpha 21 Spf Chicken Eggs N/A
    Human IFNA21-1424H Recombinant Human IFNA21 Protein (24-189 aa), His-tagged Yeast His
    Human IFNA21-41H Recombinant Human Interferon, Alpha 21 E.coli N/A
    Human IFNA21-5280HCL Recombinant Human IFNA21 293 Cell Lysate HEK293 N/A
    Human IFNA21-617H Recombinant Human IFNA21 Protein, His/GST-tagged E.coli His/GST
    Human IFNA21-6275H Recombinant Human IFNA21 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human IFNA21-77H Recombinant Human Interferon, Alpha 21 E.coli N/A

    ifna21 involved in several pathways and played different roles in them. We selected most pathways ifna21 participated on our site, such as Cytokine-cytokine receptor interaction, Regulation of autophagy, PIK-Akt signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with ifna21 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cytokine-cytokine receptor interaction CXCL6; GM2506; Ccl9; IL2RA; TNFSF9; IL12RB2; IFNW1; IL6R; Ifnlr1; BMPR1BB
    Regulation of autophagy ATG14; IFNA21; IFNA3; IFNPHI3; GABARAPA; IFNA2; ATG3; IFNA6; ATG12; Ifna15
    PIK-Akt signaling pathway GNG5; TCL1A; IKBKG; PRL; INS2; IGF1R; PPP2R5E; HGF; G6PC2; PRKCA
    Toll-like receptor signaling pathway FOS; TLR1LA; MAPK14B; LY96; PIK3R3B; PIK3CB; TLR4BB; PIK3CG; TLR7; MAP2K3
    RIG-I-like receptor signaling pathway TMEM173; NFKBIAB; IFNA10; IFNA3; NFKBIAA; IKBKG; NFKB1; IL12A; OTUD5A; NFKBIA
    Cytosolic DNA-sensing pathway IFI202B; NFKBIAB; CCL4L1; IL18; POLR2F; CCL5; IRF3; IKBKG; LOC100033925; POLR3G
    Jak-STAT signaling pathway AOX2P; IL2RGB; IL4R; CSH2; IL28RA; PRL; Ifnl2; CISHB; IFNA10; SOS1
    Natural killer cell mediated cytotoxicity PRKCA; TNFSF10; CD247; MAP2K2; RAET1D; GRB2; PRKCG; IFNA8; SHC2; SH3BP2
    Tuberculosis RFX5; PPP3R2; CASP10; cgr2b; FCGR3A; TLR9; Casp3; CAMK2B; PPP3R1; TGFB3
    Hepatitis B IFNA13; HRAS; TNF; IRF7; PTEN; IFNA6; AKT1; MAPK10; PTK2B; RELA
    Influenza A KPNA1; PLG; IL1B; IFNA1; LOC780933; IFNA2; OAS2; PRSS1; IFNG; HLA-DPA1
    Herpes simplex infection SOCS3; MCRS1; NFKBIA; EIF2AK2; SRSF5A; C3A.3; TAP2; CASP8; SRPK1A; IKBKE
    Autoi IFNA8; FAS; HLA-F; IFNA2; IFNA4; HLA-A; IFNA14; IFNA7; CD86; Ifna15
    ne thyroid disease HLA-DPB1; CD28; CD80; IFNA14; HLA-DPA1; IFNA16; HLA-DRB4; HLA-DMB; IFNA1; HLA-C

    ifna21 has several biochemical functions, for example, cytokine activity, cytokine receptor binding, type I interferon receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ifna21 itself. We selected most functions ifna21 had, and list some proteins which have the same functions with ifna21. You can find most of the proteins on our site.

    Function Related Protein
    cytokine activity GM13289; IL8L2; LFT2; BMP10; IFNB1; TNFSF10; IFNA10; TNFSF8; Cxcl15; TNFSF13B
    cytokine receptor binding MIF; IFNA5; IFNW1; IFNA14; IL15L; IL17A/F2; IFNPHI4; IFN-a; IFNA8; IL17A/F1
    type I interferon receptor binding IFNA4; IFNA7; Gm13290; GM13289; IFNB; GM13287; IFNW1; IFNPHI1; GM13288; OSTN

    ifna21 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ifna21 here. Most of them are supplied by our site. Hope this information will be useful for your research of ifna21.

    Guo, YL; Gao, MC; et al. Molecular cloning and characterization of a novel bovine IFN-epsilon. GENE 558:25-30(2015).
    Liu, R; Huang, DD; et al. Immunization with Recombinant SFTSV/NSs Protein Does Not Promote Virus Clearance in SFTSV-Infected C57BL/6J Mice. VIRAL IMMUNOLOGY 28:113-122(2015).

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