ifna21

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ifna21

Official Full Name interferon, alpha 21
Background This gene is a member of the alpha interferon gene cluster on the short arm of chromosome 9. Interferons are cytokines produced in response to viral infection that mediate the immune response and interfere with viral replication. The encoded protein is a type I interferon and may play a specific role in the antiviral response to rubella virus.
Synonyms IFNA21; interferon, alpha 21; interferon alpha-21; IFN alphaI; leukocyte interferon protein; Interferon alpha F; LeIF F; MGC126687; MGC126689; IFN-alpha-21; interferon alpha-F; leIF-F; IFN-alphaI
    • Species :
    • Human
    • Source :
    • E.coli
    • HEK293
    • Spf Chicken Eggs
    • Yeast
    • Tag :
    • His
    • GST
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human IFNA21-1424H Recombinant Human IFNA21 Protein (24-189 aa), His-tagged Yeast His
    Human IFNA21-140H Recombinant Human Interferon, Alpha 21 Spf Chicken Eggs N/A
    Human IFNA21-41H Recombinant Human Interferon, Alpha 21 E.coli N/A
    Human IFNA21-5280HCL Recombinant Human IFNA21 293 Cell Lysate HEK293 N/A
    Human IFNA21-617H Recombinant Human IFNA21 Protein, His/GST-tagged E.coli His/GST
    Human IFNA21-77H Recombinant Human Interferon, Alpha 21 E.coli N/A

    ifna21 involved in several pathways and played different roles in them. We selected most pathways ifna21 participated on our site, such as Cytokine-cytokine receptor interaction, Regulation of autophagy, PIK-Akt signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with ifna21 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cytokine-cytokine receptor interaction CCL25B; TNFSF8; EDA2R; TNFRSF8; FIGF; IL23; IL12RB1; CCR6A; CCR1L1; IFNA17
    Regulation of autophagy IFNA12; ATG13; IFNA14; IFNA2; ULK2; INS2; ULK3; ATG7; IFNPHI1; ATG10
    PIK-Akt signaling pathway GNG2; LAMB1; PKN3; IFNA5; LPAR2; PKN2; LPAR6; THBS3; IFNA6; ANGPT4
    Toll-like receptor signaling pathway LBP; CXCL10; IRF5; MAP2K2A; IFNA12; TLR2-2; TNF; CD86; PIK3R5; AKT3A
    RIG-I-like receptor signaling pathway MAPK12; MAPK12A; NFKBIAB; RELA; IFNA21; MAPK8A; RNF125; IRF7; CXCL10; TRIM25
    Cytosolic DNA-sensing pathway RIPK3; IFNA13; IFNA8; POLR3G; NFKBIA; IRF7; IFNPHI3; IFNA12; POLR1D; POLR2F
    Jak-STAT signaling pathway CCND3; Il6ra; IL20RA; IL6ST; SOCS6; CNTFR; M17; CSF3R; IFNK; IL13
    Natural killer cell mediated cytotoxicity IFNA6; PIK3R5; KIR2DL3; SHC3; TNF; IFNB1; RAET1D; CD244; ZAP70; Casp3
    Tuberculosis HLA-DQA1; CALM2; RFXAP; HLA-DRB4; HSPA9; PPP3CA; HLA-DMB; IL10RB; IL12B; RIPK2
    Hepatitis C TNFRSF1A; HRAS; IFNAR2; EIF2AK3; AKT2; NFKBIA; CLDN3; PIK3CB; PPP2R1B; CLDN23
    Hepatitis B HSPG2; NFATC3; CCNE1; FADD; IFNA8; BAX; NFATC1; PTEN; IFNA12; CCNE2
    Measles EIF2AK1; IL2RG; IFNA7; OAS1B; IL4; OAS1; CD3E; TLR9; DDX58; IL12A
    Influenza A KPNA1; PIK3CB; MAPK13; HLA-DRB1; NFKBIA; IFNA8; IFNB; HSPA6; IFNA12; TMPRSS4
    Herpes simplex infection IFNA10; EP300; IFNB1; MAPK9; TLR2-1; MHC2A; HLA-A; IFNA8; Hc; C3A.3
    Autoi IFNA5; GZMB; IFNA21; HLA-DPA1; Il2; CD40LG; IFNA6; IFNA17; IL4; TPO
    ne thyroid disease HLA-DOB; IFNA16; IFNA14; HLA-DPB1; HLA-DMB; HLA-DRB5; IFNA17; H2-Q10; HLA-DRB3; HLA-DMA

    ifna21 has several biochemical functions, for example, cytokine activity, cytokine receptor binding, type I interferon receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ifna21 itself. We selected most functions ifna21 had, and list some proteins which have the same functions with ifna21. You can find most of the proteins on our site.

    Function Related Protein
    cytokine activity GDF10; CCL19A.1; BMP8B; SCGB3A1; IFNE; TGFB3; AIMP1; IFNG1-1; Ccl27a; INHBAB
    cytokine receptor binding IFNA5; IFNA12; IL17B; IL15; IFNA8; IL17A/F3; IL17A/F2; IFNA14; IFNT2; IFNA13
    type I interferon receptor binding Gm13290; IFNA6; GM13278; GM13287; IFNA3; GM13288; RNF207B; IFNA10; GM13289; IFNA17

    ifna21 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ifna21 here. Most of them are supplied by our site. Hope this information will be useful for your research of ifna21.

    Guo, YL; Gao, MC; et al. Molecular cloning and characterization of a novel bovine IFN-epsilon. GENE 558:25-30(2015).
    Liu, R; Huang, DD; et al. Immunization with Recombinant SFTSV/NSs Protein Does Not Promote Virus Clearance in SFTSV-Infected C57BL/6J Mice. VIRAL IMMUNOLOGY 28:113-122(2015).

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