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IFNA21

  • Official Full Name

    interferon, alpha 21

  • Overview

    This gene is a member of the alpha interferon gene cluster on the short arm of chromosome 9. Interferons are cytokines produced in response to viral infection that mediate the immune response and interfere with viral replication. The encoded protein is a type I interferon and may play a specific role in the antiviral response to rubella virus.
  • Synonyms

    IFNA21; interferon, alpha 21; interferon alpha-21; IFN alphaI; leukocyte interferon protein; Interferon alpha F; LeIF F; MGC126687; MGC126689; IFN-alpha-21; interferon alpha-F; leIF-F; IFN-alphaI;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Human
  • E. coli
  • E.coli
  • HEK293
  • HEK293T
  • Spf Chicken Eggs
  • Yeast
  • His
  • His|GST
  • Myc
  • DDK
  • N/A
  • N
  • GST
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human IFNA21-77H Recombinant Human Interferon, Alpha 21 E.coli N/A
Human IFNA21-41H Recombinant Human Interferon, Alpha 21 E.coli N/A
Human IFNA21-140H Recombinant Human Interferon, Alpha 21 Spf Chicken Eggs N/A
Human IFNA21-5280HCL Recombinant Human IFNA21 293 Cell Lysate HEK293 N/A
Human IFNA21-6275H Recombinant Human IFNA21 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human IFNA21-1424H Recombinant Human IFNA21 Protein (24-189 aa), His-tagged Yeast His 24-189 aa
Human IFNA21-617H Recombinant Human IFNA21 Protein, His/GST-tagged E.coli His/GST Asp25~Glu189
Human IFNA21-3100H Recombinant Human IFNA21 Protein (Asp25-Glu189), N-GST tagged E.coli N-GST Asp25-Glu189
Human IFNA21-3069H Recombinant Human IFNA21 protein, His-tagged E.coli His 24-189aa
Human IFNA21-076H Recombinant Human IFNA21 Protein E. coli
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • IFNA21 Related Articles

IFNA21 involved in several pathways and played different roles in them. We selected most pathways IFNA21 participated on our site, such as Cytokine-cytokine receptor interaction, Regulation of autophagy, PIK-Akt signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with IFNA21 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Cytokine-cytokine receptor interactionMPL;CSF2RA;IL18RAP;ACVR1B;IL17B;OSTN;Ccl21a;BMPR1B;BMPR2A
Regulation of autophagyIFNA7;PRKAA2;ATG4C;IFNA10;IFNA17;BECN1;INSB;IFNA12;ATG13
PIK-Akt signaling pathwayGNB1;IL4R;IFNA2;FGF3;INSR;SGK1;ITGA2B;IFNAR2;PKN1
Toll-like receptor signaling pathwayTLR5B;PIK3R5;TRAF3;PIK3CA;MAPK12;MAP2K4A;CCL3L3;IFNA5;IFNA16
RIG-I-like receptor signaling pathwayMAPK9;IL8L2;NLRX1;OTUD5;TMEM173;ATG12;TRAF3;Ifna15;IFNA14
Cytosolic DNA-sensing pathwayIfna15;OSTN;POLR3H;CCL4L2;IFNA12;POLR3C;ZBP1;CCL5;POLR2K
Jak-STAT signaling pathwayIL9;EPOR;AOX3L1;IL11RA;IFNG1-2;LIFRA;SOCS4;CSH1;NT5C3
Natural killer cell mediated cytotoxicityPRF1;PIK3R2;HRAS;MAPK3;KLRA8;FCGR3B;PIK3R5;IFNB1;IFNA8
TuberculosisSPHK2;CALM3;IFNA16;CASP8;PPP3CA;FCGR2B;ATP6V0B;MAPK11;HLA-DOA
Hepatitis CNFKB1;PIK3CG;CLDN1;PPP2R2A;PPP2R1A;PIK3R3;TBK1;IFNA12;STAT2
Hepatitis BIFNAR1;STAT1;IFNA8;Casp3;RAF1;PTEN;TLR3;CASP9;TLR2
MeaslesTLR7;TNFSF10;Il2;EIF2AK2;STAT5A;TNFRSF10C;IL13;IFNA6;EIF2AK4
Influenza APIK3CG;IVNS1ABP;TLR3;DDX58;IRF7;EIF2AK1;FURIN;ACTB;IFIH1
Herpes simplex infectionTLR9;PER2;IL12BA;TBK1;BLA;TAP1;MAPK8B;IFNA14;IL12A
AutoiIFNA14;TG;Ifna15;HLA-E;FAS;HLA-DQB1;HLA-DRB4;HLA-DOA;IFNA4
ne thyroid diseaseTSHB;IFNA16;HLA-DPA1;PRF1;HLA-F;HLA-DRB4;IFNA10;HLA-DRB5;HLA-B

IFNA21 has several biochemical functions, for example, cytokine activity, cytokine receptor binding, type I interferon receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IFNA21 itself. We selected most functions IFNA21 had, and list some proteins which have the same functions with IFNA21. You can find most of the proteins on our site.

Function Related Protein
cytokine activityIfna11;TNFSF11;CCL38.1;SPP1;IL11;IL26;IL16;CCL20A.3;CTF1
cytokine receptor bindingIL17A/F1;IL17A/F2;IFNA14;IL15;IFNA3;IFNPHI1;IL17A/F3;IL21;IL17A
type I interferon receptor bindingIFNA10;GM13279;Ifna15;IFNE;IFNB;IFNA4;IFNA12;OSTN;IFNA6

IFNA21 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IFNA21 here. Most of them are supplied by our site. Hope this information will be useful for your research of IFNA21.

Guo, YL; Gao, MC; et al. Molecular cloning and characterization of a novel bovine IFN-epsilon. GENE 558:25-30(2015).
Liu, R; Huang, DD; et al. Immunization with Recombinant SFTSV/NSs Protein Does Not Promote Virus Clearance in SFTSV-Infected C57BL/6J Mice. VIRAL IMMUNOLOGY 28:113-122(2015).
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