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IKZF1

  • Official Full Name

    IKAROS family zinc finger 1

  • Overview

    Ikaros functions in the specification and the maturation of the T lymphocyte. It also interacts with a critical control element in the terminal deoxynucleotidyltransferase promoter as well as with the promoters for other genes expressed during early stages of B and T cell development.
  • Synonyms

    IKZF1; IKAROS family zinc finger 1; DNA-binding protein Ikaros; ikaros family zinc finger protein 1; lymphoid transcription factor LyF-1; zinc finger protein subfamily 1A, 1; zinc finger protein, subfamily 1A, 1 (Ikaros); LyF-1; hlk-1; Ikaros; Zfpn1a1; Znfn1a1; mKIAA4227; 5832432G11Rik; KIAA4227;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Chicken
  • Human
  • Mouse
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Mamanlian cells
  • Mammalian Cell
  • Mammalian cells
  • C
  • MYC
  • DDK
  • Flag
  • His
  • Avi
  • Myc
  • Myc|DDK
  • N/A
  • T7|His
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human IKZF1-182H Recombinant Human IKZF1 protein, T7/His-tagged E.coli T7/His
Human IKZF1-125H Recombinant Human IKZF1 protein, MYC/DDK-tagged HEK293 Myc/DDK
Human IKZF1-850HCL Recombinant Human IKZF1 cell lysate N/A
Human IKZF1-2552H Recombinant Human IKZF1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human IKZF1-4416H Recombinant Human IKZF1 protein, His-Avi-tagged E.coli His-Avi 1-477aa
Human IKZF1-9822HFL Recombinant Full Length Human IKZF1 protein, Flag-tagged Mamanlian cells Flag
Human IKZF1-3889H Recombinant Human IKZF1 Protein (Met1-Ser519), C-MYC/DDK tagged Mammalian cells C-MYC/DDK Met1-Ser519
Mouse Ikzf1-3498M Recombinant Mouse Ikzf1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Zebrafish IKZF1-8622Z Recombinant Zebrafish IKZF1 Mammalian Cell His
Chicken IKZF1-6645C Recombinant Chicken IKZF1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • IKZF1 Related Research Area

IKZF1 involved in several pathways and played different roles in them. We selected most pathways IKZF1 participated on our site, such as Calcineurin-regulated NFAT-dependent transcription in lymphocytes, which may be useful for your reference. Also, other proteins which involved in the same pathway with IKZF1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Calcineurin-regulated NFAT-dependent transcription in lymphocytesBATF3;JUNB;EGR4;DGKA;POU2F1;CSF2;CDK4;EGR1;IRF4

IKZF1 has several biochemical functions, for example, DNA binding, metal ion binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IKZF1 itself. We selected most functions IKZF1 had, and list some proteins which have the same functions with IKZF1. You can find most of the proteins on our site.

Function Related Protein
DNA bindingCHD4A;RUNX2A;HIST1H2AL;TOP1;TDEANC2;HIST2H2BE;H2AFVA;NKX2.2A;ZNF544
metal ion bindingCYB5B;NGLY1;ZNF43;ITGA1;CAR3;DYTN;ZNF484;ATMIN;LENG9
protein bindingHSFX1;IK;NOP2;PIH1D1;TRAP1;PASK;ARRB1;RPGRIP1;FBXW11
protein heterodimerization activityPDZD7;Pdgfa&Pdgfb;USF2;GABRR1;MPP7;CABYR;CHRAC1;UGT1A2;AHR
sequence-specific DNA bindingSOX21B;ZSCAN4;HLF;ZNF274;ATF6B;GATAD1;CEBP1;POU2F1B;HESX1
transcription factor activity, sequence-specific DNA bindingZKSCAN3;NFE2L2A;ZNF567;ZC3H8;ZNF134;ZRANB2;RXRA;VAV1;LMX1B
transcription regulatory region DNA bindingRNF10;TNF;ZFHX3;SP1;NR1H3;ZNF821;SOX2;Ar;NKX2-5

IKZF1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IKZF1 here. Most of them are supplied by our site. Hope this information will be useful for your research of IKZF1.

DCX; RAD51D; CTBP2; RWDD2B; FAM214B

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