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  • Official Full Name

    interleukin 17 receptor B

  • Overview

    The protein encoded by this gene is a cytokine receptor. This receptor specifically binds to IL17B and IL17E, but does not bind to IL17 and IL17C. This receptor has been shown to mediate the activation of NF-kappaB and the production of IL8 induced by IL17E. The expression of the rat counterpart of this gene was found to be significantly up-regulated during intestinal inflammation, which suggested the immunoregulatory activity of this receptor. [provided by RefSeq, Jul 2008]
  • Synonyms

    IL17RB; interleukin 17 receptor B; CRL4; EVI27; IL17BR; IL17RH1; interleukin-17 receptor B; IL-17RB; IL-17Rh1; IL-17B receptor; IL-17 receptor B; cytokine receptor CRL4; IL-17 receptor homolog 1; cytokine receptor-like 4; interleukin 17B receptor; interleukin-17B receptor; interleukin 17 receptor homolog 1;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Rhesus
  • Rhesus Macaque
  • E.coli
  • HEK293
  • Human Cell
  • Insect Cell
  • Mammalian cells
  • C
  • His
  • Fc
  • Fc|His
  • FLAG
  • hIgG
  • His (Fc)
  • Avi
  • His|T7
  • HlgG1 Fc
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human IL17RB-308H Active Recombinant Human IL17RB protein, His-tagged HEK293 His Met1-Gly289
Human IL17RB-483H Active Recombinant Human IL17RB Protein, Fc-tagged HEK293 Fc
Human IL17RB-710H Active Recombinant Human IL17RB Protein, Fc Chimera Mammalian cells Fc
Human IL17RB-484H Recombinant Human IL17RB Protein, FLAG-tagged Insect Cell FLAG
Human IL17RB-7987H Recombinant Human IL17RB protein, His & T7-tagged E.coli His/T7 Asp61~Thr200 (Accession # Q9NRM6)
Human IL17RB-41H Recombinant Human IL17RB, hIgG-His-tagged Insect Cell Fc/His
Human IL17RB-549HCL Recombinant Human IL17RB cell lysate Insect Cell N/A
Human IL17RB-871HCL Recombinant Human IL17RB cell lysate Human Cell N/A
Human IL17RB-01H Active Recombinant Human IL17RB Protein, hIgG/His-tagged Insect Cell hIgG/His
Human IL17RB-2295H Recombinant Human IL17RB Protein, His-tagged E.coli N-His Asp61-Thr200
Human IL17RB-96H Recombinant Human IL17RB Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human IL17RB-96H-B Recombinant Human IL17RB Protein Pre-coupled Magnetic Beads HEK293
Human IL17RB-0193H Recombinant Human IL17RB protein, Fc-tagged HEK293 Fc Arg18-Pro292
Mouse Il17rb-967M Active Recombinant Mouse Il17rb Protein, Fc-tagged HEK293 Fc
Mouse IL17RB-3369M Active Recombinant Mouse IL17RB protein(Met1-Gly286), His-tagged HEK293 C-His Met1-Gly286
Mouse Il17rb-7988M Recombinant Mouse Il17rb protein, His-tagged E.coli His Arg310-Leu499 (Accession # Q9JIP3)
Mouse Il17rb-475M Recombinant Mouse Il17rb, His tagged Human Cell Fc/His
Mouse IL17RB-1115MCL Recombinant Mouse IL17RB cell lysate Human Cell N/A
Rat Il17rb-7989R Recombinant Rat Il17rb protein, His-tagged E.coli His Gln166~Leu354 (Accession # B5DF15)
Rhesus IL17RB-990R Recombinant Rhesus IL17RB Protein (Met1-Gly288), HlgG1 Fc-tagged HEK293 HlgG1 Fc Met1-Gly288
Rhesus Macaque IL17RB-1198R Recombinant Rhesus IL17RB Protein, His-tagged HEK293 His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • IL17RB Related Gene Family
  • IL17RB Related Research Area

IL17RB involved in several pathways and played different roles in them. We selected most pathways IL17RB participated on our site, such as Cytokine-cytokine receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with IL17RB were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Cytokine-cytokine receptor interactionCCL20;IL-15RA;CCL4L1;TNFRSF17;CXCL3;IFNE;GHRA;CXCR3;CCL3

IL17RB has several biochemical functions, for example, cytokine receptor activity, interleukin-17 receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by IL17RB itself. We selected most functions IL17RB had, and list some proteins which have the same functions with IL17RB. You can find most of the proteins on our site.

Function Related Protein
cytokine receptor activityIL20RB;F3A;CRFB2;CRFB15;F3B;IRX1;IL17RB;IL15RA;Il4ra
interleukin-17 receptor activityIL17RC;IL17RB;IL17RE;IL17RD;IL17RA

IL17RB has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IL17RB here. Most of them are supplied by our site. Hope this information will be useful for your research of IL17RB.

RPS6KA5; hasR

  • Q&As
  • Reviews

Q&As (10)

Ask a question
Can you elaborate on the techniques employed to study the role of IL17RB in tissue-specific inflammation and immune cell recruitment? 11/17/2021

Animal models, flow cytometry, and tissue-specific knockout strategies uncover IL17RB's involvement in inflammation and cell recruitment.

How do researchers manipulate IL17RB expression and function in cellular and animal models to understand its contribution to autoimmune diseases? 07/10/2021

CRISPR/Cas9, siRNA, and gene editing techniques manipulate IL17RB to investigate its role in autoimmune disease pathogenesis.

Could you explain how patient samples and clinical data are utilized to investigate the correlation between IL17RB expression and disease severity in various inflammatory disorders? 01/06/2020

Biomarker analysis, patient stratification, and clinical correlation studies investigate IL17RB's association with disease severity.

What molecular and cellular assays are employed to explore the interaction between IL17RB and other immune receptors or cytokines? 09/15/2019

Co-receptor binding assays, protein-protein interaction studies, and functional rescue experiments reveal IL17RB's interaction partners.

What experimental strategies are used to dissect the involvement of IL17RB in tissue repair processes, such as wound healing and fibrosis? 05/23/2019

In vitro wound healing assays, fibroblast activation studies, and tissue regeneration models probe IL17RB's contribution to tissue repair.

What techniques are used to study the impact of IL17RB inhibition or activation on immune responses and inflammation in experimental settings? 07/29/2018

Blocking antibodies, receptor activation assays, and cytokine profiling reveal IL17RB's impact on immune responses.

How is the potential of IL17RB as a therapeutic target evaluated in preclinical studies, and what challenges exist in translating these findings into clinical applications? 12/31/2017

Animal models, therapeutic antibody studies, and safety assessments evaluate IL17RB-targeted therapies and clinical translation challenges.

How is the ligand binding affinity of IL17RB to different IL17 family members determined experimentally? 12/02/2017

Surface plasmon resonance, ELISA, and competitive binding assays determine IL17RB's affinity for various IL17 family members.

How do researchers investigate the role of IL17RB in cancer and tumor microenvironment modulation, and what experimental models are commonly used? 08/23/2017

Tumor xenograft models, immune cell infiltration assays, and gene expression analysis explore IL17RB's role in cancer biology.

What experimental methods are used to investigate the downstream signaling pathways activated by IL17RB, and how are these pathways integrated with other immune responses? 04/18/2017

Phosphorylation assays, gene expression profiling, and co-immunoprecipitation studies elucidate IL17RB-mediated signaling networks.

Customer Reviews (3)

Write a review

    High stability.


      Good for flow cytometry.


        Potent in anti-viral assays.

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