IL17RB
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Official Full Name
interleukin 17 receptor B -
Overview
The protein encoded by this gene is a cytokine receptor. This receptor specifically binds to IL17B and IL17E, but does not bind to IL17 and IL17C. This receptor has been shown to mediate the activation of NF-kappaB and the production of IL8 induced by IL17E. The expression of the rat counterpart of this gene was found to be significantly up-regulated during intestinal inflammation, which suggested the immunoregulatory activity of this receptor. [provided by RefSeq, Jul 2008] -
Synonyms
IL17RB;interleukin 17 receptor B;CRL4;EVI27;IL17BR;IL17RH1;interleukin-17 receptor B;IL-17RB;IL-17Rh1;IL-17B receptor;IL-17 receptor B;cytokine receptor CRL4;IL-17 receptor homolog 1;cytokine receptor-like 4;interleukin 17B receptor;interleukin-17B receptor;interleukin 17 receptor homolog 1
Recombinant Proteins
- Human
- Mouse
- Rhesus macaque
- Rat
- HEK293
- Mammalian Cells
- Insect Cells
- Human Cells
- E.coli
- His
- Fc
- Flag
- T7
- Non
- Avi
Involved Pathway
IL17RB involved in several pathways and played different roles in them. We selected most pathways IL17RB participated on our site, such as Cytokine-cytokine receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with IL17RB were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Cytokine-cytokine receptor interaction | IFN-a,PDGFC,HGF,CXCR3.2,KITB,TNFSF18,Ifnlr1,TNFSF13B,CXCL6,Cxcl15 |
Protein Function
IL17RB has several biochemical functions, for example, cytokine receptor activity,interleukin-17 receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by IL17RB itself. We selected most functions IL17RB had, and list some proteins which have the same functions with IL17RB. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| cytokine receptor activity | IL12RB1,IL13RA2,LEPR,Il4ra,GHR,IL2RGA,IL12B,CRFB6,FLT3,CD74 |
| interleukin-17 receptor activity | IL17RA,IL17RD,IL17RE,IL17RC |
Interacting Protein
IL17RB has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IL17RB here. Most of them are supplied by our site. Hope this information will be useful for your research of IL17RB.
RPS6KA5;hasR
Resources
Research Area
Multiple Sclerosis and Myelin Related MoleculesNatural Killer T (NKT) Cells
Th2 Cells
Th9 Cells
IL-17 Family Receptors
Related Services
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References
