Recombinant Human IL17RB Protein, His-tagged
Cat.No. : | IL17RB-2295H |
Product Overview : | Recombinant Human IL17RB Protein (Asp61-Thr200) with a N-His tag was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a cytokine receptor. This receptor specifically binds to IL17B and IL17E, but does not bind to IL17 and IL17C. This receptor has been shown to mediate the activation of NF-kappaB and the production of IL8 induced by IL17E. The expression of the rat counterpart of this gene was found to be significantly up-regulated during intestinal inflammation, which suggested the immunoregulatory activity of this receptor. |
Source : | E. coli |
Species : | Human |
Tag : | N-His |
Form : | Freeze-dried powder |
Molecular Mass : | Predicted Molecular Mass: 19.4 kDa Accurate Molecular Mass: 19 kDa |
Protein length : | Asp61-Thr200 |
Endotoxin : | <1.0 EU per 1µg (determined by the LAL method). |
Purity : | > 80% |
Applications : | Cell culture; Activity Assays. |
Stability : | The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. |
Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months. |
Storage Buffer : | 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300. |
Reconstitution : | Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex. |
Gene Name : | IL17RB interleukin 17 receptor B [ Homo sapiens (human) ] |
Official Symbol : | IL17RB |
Synonyms : | IL17RB; interleukin 17 receptor B; IL17BR, interleukin 17B receptor; interleukin-17 receptor B; CRL4; EVI27; IL17RH1; IL-17RB; IL-17Rh1; IL-17B receptor; IL-17 receptor B; cytokine receptor CRL4; IL-17 receptor homolog 1; cytokine receptor-like 4; interleukin 17B receptor; interleukin-17B receptor; interleukin 17 receptor homolog 1; IL17BR; MGC5245; |
Gene ID : | 55540 |
mRNA Refseq : | NM_018725 |
Protein Refseq : | NP_061195 |
MIM : | 605458 |
UniProt ID : | Q9NRM6 |
Products Types
◆ Recombinant Protein | ||
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IL17RB-990R | Recombinant Rhesus IL17RB Protein (Met1-Gly288), HlgG1 Fc-tagged | +Inquiry |
IL17RB-3369M | Active Recombinant Mouse IL17RB protein(Met1-Gly286), His-tagged | +Inquiry |
Il17rb-967M | Active Recombinant Mouse Il17rb Protein, Fc-tagged | +Inquiry |
◆ Lysates | ||
IL17RB-871HCL | Recombinant Human IL17RB cell lysate | +Inquiry |
IL17RB-549HCL | Recombinant Human IL17RB cell lysate | +Inquiry |
IL17RB-1115MCL | Recombinant Mouse IL17RB cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (10)
Ask a questionAnimal models, flow cytometry, and tissue-specific knockout strategies uncover IL17RB's involvement in inflammation and cell recruitment.
CRISPR/Cas9, siRNA, and gene editing techniques manipulate IL17RB to investigate its role in autoimmune disease pathogenesis.
Biomarker analysis, patient stratification, and clinical correlation studies investigate IL17RB's association with disease severity.
Co-receptor binding assays, protein-protein interaction studies, and functional rescue experiments reveal IL17RB's interaction partners.
In vitro wound healing assays, fibroblast activation studies, and tissue regeneration models probe IL17RB's contribution to tissue repair.
Blocking antibodies, receptor activation assays, and cytokine profiling reveal IL17RB's impact on immune responses.
Animal models, therapeutic antibody studies, and safety assessments evaluate IL17RB-targeted therapies and clinical translation challenges.
Surface plasmon resonance, ELISA, and competitive binding assays determine IL17RB's affinity for various IL17 family members.
Tumor xenograft models, immune cell infiltration assays, and gene expression analysis explore IL17RB's role in cancer biology.
Phosphorylation assays, gene expression profiling, and co-immunoprecipitation studies elucidate IL17RB-mediated signaling networks.
Customer Reviews (3)
Write a reviewHigh stability.
Good for flow cytometry.
Potent in anti-viral assays.
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