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  • Official Full Name

    interleukin 1 receptor accessory protein-like 2

  • Overview

    The protein encoded by this gene is a member of the interleukin 1 receptor family. This protein is similar to the interleukin 1 accessory proteins, and is most closely related to interleukin 1 receptor accessory protein-like 1 (IL1RAPL1). This gene and IL1RAPL1 are located at a region on chromosome X that is associated with X-linked non-syndromic mental retardation.
  • Synonyms

    IL1RAPL2; interleukin 1 receptor accessory protein-like 2; X-linked interleukin-1 receptor accessory protein-like 2; IL 1R9; IL1R9; IL1RAPL 2; TIGIRR 1; IL-1R-9; IL-1RAPL-2; IL-1-RAPL-2; interleukin 1 receptor 9; interleukin-1 receptor 9; IL1RAPL-2-relate; IL-1R9; TIGIRR-1; IL1RAPL-2;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Human
  • Zebrafish
  • E.coli
  • HEK293
  • Human Cell
  • Mammalian Cell
  • C
  • His
  • Fc
  • His|T7
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human IL1RAPL2-778H Recombinant Human IL1RAPL2, Fc tagged Human Cell Fc
Human IL1RAPL2-3147H Recombinant Human IL1RAPL2 protein(Met1-Glu356), His-tagged HEK293 C-His Met1-Glu356
Human IL1RAPL2-2165HCL Recombinant Human IL1RAPL2 cell lysate Human Cell N/A
Human IL1RAPL2-2913HCL Recombinant Human IL1RAPL2 cell lysate Human Cell N/A
Human IL1RAPL2-3551H Recombinant Human IL1RAPL2 Protein (Ser161-Thr330), N-His tagged E.coli N-His Ser161-Thr330
Human IL1RAPL2-1574H Recombinant Human IL1RAPL2 protein, His & T7-tagged E.coli His/T7 Ser161~Thr330 (Accession # Q9NP60)
Zebrafish IL1RAPL2-7246Z Recombinant Zebrafish IL1RAPL2 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • IL1RAPL2 Related Articles
  • IL1RAPL2 Related Research Area

IL1RAPL2 involved in several pathways and played different roles in them. We selected most pathways IL1RAPL2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with IL1RAPL2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

IL1RAPL2 has several biochemical functions, for example, interleukin-1 receptor activity, interleukin-1, Type II, blocking receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by IL1RAPL2 itself. We selected most functions IL1RAPL2 had, and list some proteins which have the same functions with IL1RAPL2. You can find most of the proteins on our site.

Function Related Protein
interleukin-1 receptor activityIL18R1;IL1R1;IL1RAP;IL1RAPL2;IL1RAPL1A;IL1RL2;IL1RL1;IL1R2
interleukin-1, Type II, blocking receptor activityIL1RAPL2;IL1R2

IL1RAPL2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IL1RAPL2 here. Most of them are supplied by our site. Hope this information will be useful for your research of IL1RAPL2.

Dinopoulos, A; Stefanou, MI; et al. A Case of Startle Epilepsy Associated With IL1RAPL1 Gene Deletion. PEDIATRIC NEUROLOGY 51:271-274(2014).
Yamamoto, T; Wilsdon, A; et al. An emerging phenotype of Xq22 microdeletions in females with severe intellectual disability, hypotonia and behavioral abnormalities. JOURNAL OF HUMAN GENETICS 59:300-306(2014).
  • Q&As
  • Reviews

Q&As (10)

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How does IL1RAPL2 affect T-cell activation? 08/23/2021

IL1RAPL2 enhances T-cell activation by modulating calcium signaling.

What role does IL1RAPL2 play in immune responses? 07/29/2020

IL1RAPL2 modulates dendritic cell maturation in immune responses.

Is IL1RAPL2 involved in autoimmune diseases? 06/04/2020

IL1RAPL2 is implicated in multiple sclerosis.

What is the subcellular localization of IL1RAPL2? 12/31/2019

IL1RAPL2 is localized in the cytoplasm and cell membrane.

Does IL1RAPL2 interact with any cytokines? 03/01/2019

IL1RAPL2 does not directly interact with cytokines but influences their signaling.

Are there post-translational modifications of IL1RAPL2? 07/24/2018

IL1RAPL2 undergoes phosphorylation and ubiquitination.

Is IL1RAPL2 expression altered in cancer? 06/28/2018

IL1RAPL2 expression is upregulated in certain types of cancer.

How does IL1RAPL2 influence cell migration? 06/17/2018

IL1RAPL2 promotes cell migration through actin remodeling.

How is IL1RAPL2 expression regulated in inflammatory conditions? 06/21/2016

IL1RAPL2 expression is upregulated by pro-inflammatory cytokines.

Does IL1RAPL2 have any enzymatic activity? 06/11/2016

IL1RAPL2 does not have enzymatic activity.

Customer Reviews (3)

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    Suitable for co-immunoprecipitation.


      High specificity.


        Good for flow cytometry.

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