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Recombinant Human IL1RAPL2 protein, His & T7-tagged

Cat.No. : IL1RAPL2-1574H
Product Overview : Recombinant Human IL1RAPL2 aa. (Ser161~Thr330 (Accession # Q9NP60)) fused with N-terminal His & T7 tag was produced in E. coli cells.
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Description : The protein encoded by this gene is a member of the interleukin 1 receptor family. This protein is similar to the interleukin 1 accessory proteins, and is most closely related to interleukin 1 receptor accessory protein-like 1 (IL1RAPL1). This gene and IL1RAPL1 are located at a region on chromosome X that is associated with X-linked non-syndromic cognitive disability.
Source : E. coli
Species : Human
Tag : His&T7
Form : Freeze-dried powder
Molecular Mass : 27kDa as determined by SDS-PAGE reducing conditions.
Protein length : Ser161~Thr330
Endotoxin : <1.0EU per 1ug (determined by the LAL method)
Purity : >95%
Applications : SDS-PAGE; WB; ELISA; IP.
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
Storage buffer : Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
Reconstitution : Reconstitute in sterile PBS, pH7.2-pH7.4.
Isoelectric Point : 4.9
Gene Name : IL1RAPL2 interleukin 1 receptor accessory protein like 2 [ Homo sapiens (human) ]
Official Symbol : IL1RAPL2
Synonyms : IL1RAPL2; interleukin 1 receptor accessory protein like 2; IL1R9; IL-1R9; TIGIRR-1; IL1RAPL-2; X-linked interleukin-1 receptor accessory protein-like 2; IL-1 receptor accessory protein-like 2; IL-1R-9; IL1RAPL-2-related protein; interleukin 1 receptor 9; three immunoglobulin domain-containing IL-1 receptor-related 1
Gene ID : 26280
mRNA Refseq : NM_017416.1
Protein Refseq : NP_059112.1
UniProt ID : Q9NP60

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Customer Reviews (3)

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Reviews
07/02/2022

    Suitable for co-immunoprecipitation.

    11/09/2020

      High specificity.

      11/23/2016

        Good for flow cytometry.

        Q&As (10)

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        How does IL1RAPL2 affect T-cell activation? 08/23/2021

        IL1RAPL2 enhances T-cell activation by modulating calcium signaling.

        What role does IL1RAPL2 play in immune responses? 07/29/2020

        IL1RAPL2 modulates dendritic cell maturation in immune responses.

        Is IL1RAPL2 involved in autoimmune diseases? 06/04/2020

        IL1RAPL2 is implicated in multiple sclerosis.

        What is the subcellular localization of IL1RAPL2? 12/31/2019

        IL1RAPL2 is localized in the cytoplasm and cell membrane.

        Does IL1RAPL2 interact with any cytokines? 03/01/2019

        IL1RAPL2 does not directly interact with cytokines but influences their signaling.

        Are there post-translational modifications of IL1RAPL2? 07/24/2018

        IL1RAPL2 undergoes phosphorylation and ubiquitination.

        Is IL1RAPL2 expression altered in cancer? 06/28/2018

        IL1RAPL2 expression is upregulated in certain types of cancer.

        How does IL1RAPL2 influence cell migration? 06/17/2018

        IL1RAPL2 promotes cell migration through actin remodeling.

        How is IL1RAPL2 expression regulated in inflammatory conditions? 06/21/2016

        IL1RAPL2 expression is upregulated by pro-inflammatory cytokines.

        Does IL1RAPL2 have any enzymatic activity? 06/11/2016

        IL1RAPL2 does not have enzymatic activity.

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