Recombinant Human IL1RAPL2 protein(Met1-Glu356), hFc-tagged

Cat.No. : IL1RAPL2-778H
Product Overview : Recombinant Human IL1R9 (NP_059112.1)(Met 1-Glu 356) was expressed in HEK293 with the fused Fc region of Human IgG1 at the C-terminus.
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Source : HEK293
Species : Human
Tag : C-hFc
Protein length : Met1-Glu356
Form : Lyophilized from sterile 100mM Glycine, 10mM NaCl, 50mM Tris, pH 7.5. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Bio-activity : Measured by its ability to bind biotinylated human IL1α in functional ELISA.
Molecular Mass : The recombinant human IL1R9/Fc is a disulfide-linked homodimeric protein generated by proteolytic removal of the signal peptide. The reduced monomer consists of 578 amino acids and has a predicted molecular mass of 66 kDa. In SDS-PAGE, the apparent molecular mass of rhIL1R9/Fc monomer is approximately 80-85 kDa due to glycosylation.
Endotoxin : < 1.0 EU per μg of the protein as determined by the LAL method
Purity : > 95 % as determined by SDS-PAGE
Storage : Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.
Gene Name : IL1RAPL2 interleukin 1 receptor accessory protein-like 2 [ Homo sapiens ]
Official Symbol : IL1RAPL2
Synonyms : IL1RAPL2; interleukin 1 receptor accessory protein-like 2; X-linked interleukin-1 receptor accessory protein-like 2; IL 1R9; IL1R9; IL1RAPL 2; TIGIRR 1; IL-1R-9; IL-1RAPL-2; IL-1-RAPL-2; interleukin 1 receptor 9; interleukin-1 receptor 9; IL1RAPL-2-related protein; IL-1 receptor accessory protein-like 2; three immunoglobulin domain-containing IL-1 receptor-related 1; IL-1R9; TIGIRR-1; IL1RAPL-2;
Gene ID : 26280
mRNA Refseq : NM_017416
Protein Refseq : NP_059112
MIM : 300277
UniProt ID : Q9NP60

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (10)

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How does IL1RAPL2 affect T-cell activation? 08/23/2021

IL1RAPL2 enhances T-cell activation by modulating calcium signaling.

What role does IL1RAPL2 play in immune responses? 07/29/2020

IL1RAPL2 modulates dendritic cell maturation in immune responses.

Is IL1RAPL2 involved in autoimmune diseases? 06/04/2020

IL1RAPL2 is implicated in multiple sclerosis.

What is the subcellular localization of IL1RAPL2? 12/31/2019

IL1RAPL2 is localized in the cytoplasm and cell membrane.

Does IL1RAPL2 interact with any cytokines? 03/01/2019

IL1RAPL2 does not directly interact with cytokines but influences their signaling.

Are there post-translational modifications of IL1RAPL2? 07/24/2018

IL1RAPL2 undergoes phosphorylation and ubiquitination.

Is IL1RAPL2 expression altered in cancer? 06/28/2018

IL1RAPL2 expression is upregulated in certain types of cancer.

How does IL1RAPL2 influence cell migration? 06/17/2018

IL1RAPL2 promotes cell migration through actin remodeling.

How is IL1RAPL2 expression regulated in inflammatory conditions? 06/21/2016

IL1RAPL2 expression is upregulated by pro-inflammatory cytokines.

Does IL1RAPL2 have any enzymatic activity? 06/11/2016

IL1RAPL2 does not have enzymatic activity.

Customer Reviews (3)

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Reviews
07/02/2022

    Suitable for co-immunoprecipitation.

    11/09/2020

      High specificity.

      11/23/2016

        Good for flow cytometry.

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