• Official Full Name

    interleukin 20

  • Background

    Human IL-20 or Interleukin-20, also known as Cytokine Zcyto10, is a 176 amino acid cytokine protein expressed from the IL20 gene located at locus 1q32 on chromosome 1. After initial synthesis of the protein, it undergoes proteolytic cleavage where the 24 residue signal sequence is cleaved, allowing for the proper folding and maturation of the IL-20 cytokine. Recent studies have determined that IL-20, belonging to the IL-10 family, may be involved in epidermal function and psoriasis via signal transduction through Signal Transducer and Activator of Transcription 3 (STAT3) in keratinocytes. It is expressed at very low levels in skin, trachea and other tissues.
  • Synonyms

    UNQ852/PRO1801; IL-20; IL10D; ZCYTO10; cytokine Zcyto10; four alpha helix cytokine; interleukin-20;
    • Type:
    • Recombinant Proteins
    • Cell & Tissue Lysates
    • GMP Proteins
    • Species :
    • Horse
    • Human
    • Mouse
    • Rat
    • Source :
    • E. coli
    • E.coli
    • HEK293
    • HEK293F
    • HEK293T
    • Human Cell
    • Tag :
    • Fc
    • GST
    • His
    • His(C
    • ter)
    • Myc
    • DDK
    • N/A
    • N
    • Strep II
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Horse IL20-1028H Recombinant Horse IL20 Protein, His-tagged E.coli N-His
    Human IL20-5233HCL Recombinant Human IL20 293 Cell Lysate HEK293 N/A
    Human IL20-29664TH Recombinant Human IL20 E.coli N/A
    Human IL20-268H Recombinant Human IL20, StrepII-tagged Human Cell Strep II
    Human IL20-160H Recombinant Human IL20 Protein E.coli
    Human IL20-14181H Recombinant Human IL20, GST-tagged E.coli GST
    Human IL20-588H Recombinant Human IL20 protein, His-tagged E.coli His
    Human IL20-4333HG GMP Recombinant Human IL20 protein E.coli N/A
    Human IL20-172H Recombinant Active Human IL20 Protein, His-tagged(C-ter) E.coli His(C-ter)
    Human IL20-29777TH Recombinant Human IL20, His-tagged His
    Human IL20-965H Recombinant Human IL20 Protein E.coli N/A
    Human IL20-278H Recombinant Human IL20 protein E.coli N/A
    Human IL20-7346H Recombinant Human IL20, None tagged E.coli N/A
    Human IL20-500H Active Recombinant Human Interleukin 20 E.coli N/A
    Human IL20-1931H Recombinant Human IL20 protein, His-tagged HEK293 His
    Mouse Il20-74M Recombinant Mouse Interleukin 20 E.coli N/A
    Mouse IL20-1818M Recombinant Mouse IL20 Protein E.coli N/A
    Mouse Il20-1029M Recombinant Mouse Il20 Protein, His-tagged HEK293F N-His
    Mouse Il20-3509M Recombinant Mouse Il20 Protein E. coli
    Mouse Il20-01M Active Recombinant Mouse Il20 Protein, His-Tagged E.coli His
    Mouse Il20-3510M Recombinant Mouse Il20 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Mouse Il20-1671M Recombinant Mouse Il20 Protein, His-tagged E.coli N-His
    Mouse Il20-173M Recombinant Active Mouse IL20 Protein, His-tagged(C-ter) E.coli His(C-ter)
    Rat Il20-47R Recombinant Rat Il20, None tagged E.coli Fc
    • Involved Pathway
    • Protein Function
    • Interacting Protein
    • Il20 Related Gene Family
    • Il20 Related Research Area

    Il20 involved in several pathways and played different roles in them. We selected most pathways Il20 participated on our site, such as Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with Il20 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cytokine-cytokine receptor interactionTNFRSF25;IFNA1;OSTN;IL11;CCL24;Ifna11;IL17RB;CXCL8;CCL19
    Jak-STAT signaling pathwayLEPR;M17;AKT2;PIK3R3A;CRLF2;PIK3R2;IL10RA;IRX1;PIAS4A

    Il20 has several biochemical functions, for example, cytokine activity, interleukin-20 receptor binding, interleukin-22 receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Il20 itself. We selected most functions Il20 had, and list some proteins which have the same functions with Il20. You can find most of the proteins on our site.

    Function Related Protein
    cytokine activityWNT5A;GPI1;CCL4;GDF11;C1QTNF4;BMP5;GM13288;IL17B;ILTIFB
    interleukin-20 receptor binding
    interleukin-22 receptor bindingIL20;IL22

    Il20 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Il20 here. Most of them are supplied by our site. Hope this information will be useful for your research of Il20.

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