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  • Official Full Name

    interleukin 20

  • Overview

    Human IL-20 or Interleukin-20, also known as Cytokine Zcyto10, is a 176 amino acid cytokine protein expressed from the IL20 gene located at locus 1q32 on chromosome 1. After initial synthesis of the protein, it undergoes proteolytic cleavage where the 24 residue signal sequence is cleaved, allowing for the proper folding and maturation of the IL-20 cytokine. Recent studies have determined that IL-20, belonging to the IL-10 family, may be involved in epidermal function and psoriasis via signal transduction through Signal Transducer and Activator of Transcription 3 (STAT3) in keratinocytes. It is expressed at very low levels in skin, trachea and other tissues.
  • Synonyms

    UNQ852/PRO1801; IL-20; IL10D; ZCYTO10; cytokine Zcyto10; four alpha helix cytokine; interleukin-20;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • GMP Proteins
  • Horse
  • Human
  • Mouse
  • Rat
  • E. coli
  • E.coli
  • HEK293
  • HEK293F
  • HEK293T
  • Human Cell
  • C
  • His
  • Fc
  • GST
  • His(C
  • ter)
  • Myc
  • DDK
  • N/A
  • N
  • Strep II
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human IL20-500H Active Recombinant Human Interleukin 20 E.coli N/A
Human IL20-588H Recombinant Human IL20 protein, His-tagged E.coli His Leu25~Glu176
Human IL20-965H Recombinant Human IL20 Protein E.coli N/A
Human IL20-29664TH Recombinant Human IL20 E.coli N/A
Human IL20-14181H Recombinant Human IL20, GST-tagged E.coli GST 26-176a.a.
Human IL20-268H Recombinant Human IL20, StrepII-tagged Human Cell Strep II 34-179, 146 a.a.
Human IL20-29777TH Recombinant Human IL20, His-tagged His
Human IL20-278H Recombinant Human IL20 protein E.coli N/A 153
Human IL20-7346H Active Recombinant Human IL20 protein(Leu25-Glu176) E. coli N/A Leu25-Glu176
Human IL20-5233HCL Recombinant Human IL20 293 Cell Lysate HEK293 N/A
Human IL20-160H Recombinant Human IL20 Protein E.coli
Human IL20-4333HG Active GMP Recombinant Human IL20 protein E.coli N/A
Human IL20-172H Recombinant Active Human IL20 Protein, His-tagged(C-ter) E.coli His(C-ter)
Human IL20-1931H Active Recombinant Human IL20 protein, His-tagged HEK293 His Leu25-Glu176
Human IL20-240H Active Recombinant Human IL20 Protein (Leu25-Glu176), C-His tagged, Animal-free, Carrier-free E.coli C-His Leu25-Glu176
Human IL20-3566H Recombinant Human IL20 Protein (Leu25-Glu176), C-His tagged E.coli C-His Leu25-Glu176
Human IL20-3565H Recombinant Human IL20 Protein (Gly24-Glu176), N-His tagged E.coli N-His Gly24-Glu176
Mouse Il20-01M Active Recombinant Mouse Il20 Protein, His-Tagged E.coli His
Mouse Il20-74M Recombinant Mouse Interleukin 20 E.coli N/A
Mouse IL20-1818M Recombinant Mouse IL20 Protein E.coli N/A
Mouse Il20-262M Active Recombinant Mouse Il20 Protein (Leu25-Leu176), C-His tagged, Animal-free, Carrier-free E.coli C-His Leu25-Leu176
Mouse Il20-3509M Active Recombinant Mouse Il20 Protein E. coli Leu25-Glu176
Mouse Il20-1029M Recombinant Mouse Il20 Protein, His-tagged HEK293F N-His Leu25-Leu176
Mouse Il20-3510M Recombinant Mouse Il20 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse Il20-1671M Recombinant Mouse Il20 Protein, His-tagged E.coli N-His Leu25-Leu176
Mouse Il20-173M Recombinant Active Mouse IL20 Protein, His-tagged(C-ter) E.coli His(C-ter)
Rat Il20-47R Recombinant Rat Il20, None tagged E.coli Fc
Rat IL20-1033R Recombinant Rat IL20 protein(Leu25-Leu176) E. coli N/A Leu25-Leu176
Horse IL20-1028H Recombinant Horse IL20 Protein, His-tagged E.coli N-His Leu25-Glu176
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Il20 Related Gene Family
  • Il20 Related Research Area

Il20 involved in several pathways and played different roles in them. We selected most pathways Il20 participated on our site, such as Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with Il20 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Cytokine-cytokine receptor interactionTNFSF13;IL17RB;AMHR2;NGFR;IFNA14;CLCF1;IL10;LIFRA;IL15
Jak-STAT signaling pathwayIL20RA;IFNA4;CCND1;IL2RGB;IFNG;CSF3;IL11;IL24;IFNA2

Il20 has several biochemical functions, for example, cytokine activity, interleukin-20 receptor binding, interleukin-22 receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Il20 itself. We selected most functions Il20 had, and list some proteins which have the same functions with Il20. You can find most of the proteins on our site.

Function Related Protein
interleukin-20 receptor binding
interleukin-22 receptor bindingIL22;IL20

Il20 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Il20 here. Most of them are supplied by our site. Hope this information will be useful for your research of Il20.

  • Q&As
  • Reviews

Q&As (5)

Ask a question
How does IL-20 influence tissue repair and regeneration? 03/20/2022

IL-20 has been implicated in tissue repair processes, and harnessing its properties may have implications for regenerative medicine.

How is IL-20 protein clinically applied in treating autoimmune diseases? 01/12/2022

IL-20 is being explored as a potential therapeutic target in autoimmune diseases due to its involvement in immune system regulation.

In what ways does IL-20 contribute to inflammatory responses? 08/01/2020

IL-20 is known to promote inflammation, and understanding its mechanisms may lead to targeted anti-inflammatory therapies.

Are there any ongoing clinical trials involving IL-20 protein? 03/21/2019

Yes, there are several clinical trials exploring the safety and efficacy of IL-20 inhibitors in various disease contexts.

Can IL-20 be a target for personalized medicine in autoimmune conditions? 01/17/2016

Tailoring treatments based on individual IL-20 levels and responses is a potential avenue for personalized medicine.

Customer Reviews (3)

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    The reliability and reproducibility of the IL20 Protein's performance make it a go-to option for WB experiments.


      The IL20 protein is of exceptional quality and will undoubtedly meet my experimental needs with utmost reliability and accuracy.


        By utilizing the IL20 protein in my experiments, I can trust that I am working with a product of the highest caliber, backed by a company dedicated to delivering exceptional quality and support.

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