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Active Recombinant Mouse Il20 Protein, His-Tagged

Cat.No. : Il20-01M
Product Overview : Recombinant mouse Il20 Protein, His-tagged was expressed in E. coli cell
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Description : Interleukin 20 (IL20) is a cytokine structurally related to interleukin 10 (IL-10). This cytokine has been shown to transduce its signal through signal transducer and activator of transcription 3 (STAT3) in keratinocytes. A specific receptor for this cytokine is found to be expressed in skin and upregulated dramatically in psoriatic skin, suggesting a role for this protein in epidermal function and psoriasis.
Source : Escherichia coli
Species : Mouse
Tag : His
Form : Lyophilized powder
AA Sequence : MLKTLHLGSCVITANLQAIQKEFSE IRDSVQAEDTNIDIRILRTTESLKD IKSLDRCCFLRHLVRFYLDRVFKVY QTPDHHTLRKISSLANSFLIIKK
DLSVCHSHMACHCGEEAMEKYNQIL SHFIELELQAAVVKALGELGILLRW MEEML with polyhistidine tag at the C-terminus
Endotoxin : <0.1 EU per 1 μg of the protein by the LAL method.
Bio-activity : Measure by its ability to induce proliferation in BaF3 cells transfected with human IL-20 R alpha and human IL-20 R beta. The ED50 for this effect is <2 ng/mL.
Purity : >98% as determined by SDS-PAGE. Ni-NTA chromatography
Storage Buffer : The protein was lyophilized from a solution containing 1X PBS, pH 7.4.
Reconstitution : It is recommended to reconstitute the lyophilized protein in sterile H2O to a concentration not less than 100 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.
Storage : Lyophilized protein should be stored at -20°C. Upon reconstitution, protein aliquots should be stored at -20°C or -80°C.
Notes : Please use within one month after protein reconstitution.
Gene Name : Il20 interleukin 20 [ Mus musculus (house mouse) ]
Official Symbol : Il20
Synonyms : If2d; Zcyto10
Gene ID : 58181
mRNA Refseq : NM_001311091.1
Protein Refseq : NP_001298020.1
UniProt ID : Q9JKV9

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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How does IL-20 influence tissue repair and regeneration? 03/20/2022

IL-20 has been implicated in tissue repair processes, and harnessing its properties may have implications for regenerative medicine.

How is IL-20 protein clinically applied in treating autoimmune diseases? 01/12/2022

IL-20 is being explored as a potential therapeutic target in autoimmune diseases due to its involvement in immune system regulation.

In what ways does IL-20 contribute to inflammatory responses? 08/01/2020

IL-20 is known to promote inflammation, and understanding its mechanisms may lead to targeted anti-inflammatory therapies.

Are there any ongoing clinical trials involving IL-20 protein? 03/21/2019

Yes, there are several clinical trials exploring the safety and efficacy of IL-20 inhibitors in various disease contexts.

Can IL-20 be a target for personalized medicine in autoimmune conditions? 01/17/2016

Tailoring treatments based on individual IL-20 levels and responses is a potential avenue for personalized medicine.

Customer Reviews (3)

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Reviews
04/14/2023

    The reliability and reproducibility of the IL20 Protein's performance make it a go-to option for WB experiments.

    12/13/2022

      The IL20 protein is of exceptional quality and will undoubtedly meet my experimental needs with utmost reliability and accuracy.

      06/25/2021

        By utilizing the IL20 protein in my experiments, I can trust that I am working with a product of the highest caliber, backed by a company dedicated to delivering exceptional quality and support.

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