Recombinant Human IL20
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Cat.No. : | IL20-29664TH Optional Service: Optional requirements on this protein |
Product Overview : | Recombinant full length protein (Human)The recombinant protein is a 35.2 kDa homodimer consisting of two 153 amino acid polypeptide chains. |
Description : | The protein encoded by this gene is a cytokine structurally related to interleukin 10 (IL10). This cytokine has been shown to transduce its signal through signal transducer and activator of transcription 3 (STAT3) in keratinocytes. A specific receptor for this cytokine is found to be expressed in skin and upregulated dramatically in psoriatic skin, suggesting a role for this protein in epidermal function and psoriasis. |
Source : | E. coli |
Tissue specificity : | Expressed at very low levels in skin, trachea, and other tissues. |
Biological activity : | Biological activity determined by its ability to activate STAT following receptor ligand interaction. |
Form : | Lyophilised:Reconstitute to 1mg/ml using sterile water. |
Storage : | The lyophilized protein is stable for a few weeks at room temperature, but best stored at -20°C. |
Sequences of amino acids : | MLKTLNLGSC VIATNLQEIR NGFSEIRGSV QAKDGNIDIR ILRRTESLQD TKPANRCCLL RHLLRLYLDR VFKNYQTPDH YTLRKISSLA NSFLTIKKDL RLCHAHMTCH CGEEAMKKYS QILSHFEKLE PQAAVVKALG ELDILLQWME ETE |
Sequence Similarities : | Belongs to the IL-10 family. |
Gene Name : | IL20 interleukin 20 [ Homo sapiens ] |
Official Symbol : | IL20 |
Synonyms : | IL20; interleukin 20; interleukin-20; IL 20; IL10D; ZCYTO10; |
Gene ID : | 50604 |
mRNA Refseq : | NM_018724 |
Protein Refseq : | NP_061194 |
MIM : | 605619 |
Uniprot ID : | Q9NYY1 |
Chromosome Location : | 1q32 |
Pathway : | Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Jak-STAT signaling pathway, organism-specific biosystem; Jak-STAT signaling pathway, conserved biosystem; |
Function : | cytokine activity; interleukin-20 receptor binding; receptor binding; |
◆ Recombinant Protein
IL20-160H | Recombinant Human IL20 Protein | +Inquiry |
IL20-1818M | Recombinant Mouse IL20 Protein | +Inquiry |
Il20-3509M | Recombinant Mouse Il20 Protein | +Inquiry |
Il20-1029M | Recombinant Mouse Il20 Protein, His-tagged | +Inquiry |
Il20-3510M | Recombinant Mouse Il20 Protein, Myc/DDK-tagged | +Inquiry |
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◆ Lysates
IL20-5233HCL | Recombinant Human IL20 293 Cell Lysate | +Inquiry |
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IL10IL10RAIL10RBIL11IL11RAIl11ra1IL12IL12AIL12BIL12RB1IL13IL13RA1IL13RA2IL15IL15RAIL16IL17AIL17BIl17cIL17DIl17fIL17RAIL17RDIL18IL18BPIL18R1IL18RAPIl19Il1aIl1bIL1F10IL1R1Il1r2IL1RAPIL1RAPL1IL1RAPL2IL1RL1IL1RL2Il1rnIL2Il20IL20RAIL21IL21RIL22IL22BPIL22RA1IL22RA2IL23AIL24Il25IL27IL27RAIL28AIl28bIL29IL2RAIL2RBIl2rgIL3IL31IL32Il33Il34IL3RAIL4IL4RIl4raIl5IL5RAIl6IL6RIl6raIL6STIl7IL7RIL8IL9IL36AIl12rb2IL17RBIL23RIL26IL31RAIL36BIL36GIL36RNIL37IL9RIL17RCIL17REIL28RAIL4I1IL20RBIL17RELIl11ra2IL27bIL7RAIl23a&Il12b
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