Recombinant Human IL20 IL20-29664TH

Recombinant Human IL20

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Cat.No. : IL20-29664TH Optional Service: Optional requirements on this protein
Product Overview : Recombinant full length protein (Human)The recombinant protein is a 35.2 kDa homodimer consisting of two 153 amino acid polypeptide chains.
Description : The protein encoded by this gene is a cytokine structurally related to interleukin 10 (IL10). This cytokine has been shown to transduce its signal through signal transducer and activator of transcription 3 (STAT3) in keratinocytes. A specific receptor for this cytokine is found to be expressed in skin and upregulated dramatically in psoriatic skin, suggesting a role for this protein in epidermal function and psoriasis.
Source : E. coli
Tissue specificity : Expressed at very low levels in skin, trachea, and other tissues.
Biological activity : Biological activity determined by its ability to activate STAT following receptor ligand interaction.
Form : Lyophilised:Reconstitute to 1mg/ml using sterile water.
Storage : The lyophilized protein is stable for a few weeks at room temperature, but best stored at -20°C.
Sequences of amino acids : MLKTLNLGSC VIATNLQEIR NGFSEIRGSV QAKDGNIDIR ILRRTESLQD TKPANRCCLL RHLLRLYLDR VFKNYQTPDH YTLRKISSLA NSFLTIKKDL RLCHAHMTCH CGEEAMKKYS QILSHFEKLE PQAAVVKALG ELDILLQWME ETE
Sequence Similarities : Belongs to the IL-10 family.
Gene Name : IL20 interleukin 20 [ Homo sapiens ]
Official Symbol : IL20
Synonyms : IL20; interleukin 20; interleukin-20; IL 20; IL10D; ZCYTO10;
Gene ID : 50604
mRNA Refseq : NM_018724
Protein Refseq : NP_061194
MIM : 605619
Uniprot ID : Q9NYY1
Chromosome Location : 1q32
Pathway : Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Jak-STAT signaling pathway, organism-specific biosystem; Jak-STAT signaling pathway, conserved biosystem;
Function : cytokine activity; interleukin-20 receptor binding; receptor binding;
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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