Recombinant Human IL20

• Cat.No.: IL20-29664TH
• Product Overview: Recombinant full length protein (Human)The recombinant protein is a 35.2 kDa homodimer consisting of two 153 amino acid polypeptide chains.

Specification

• Description: The protein encoded by this gene is a cytokine structurally related to interleukin 10 (IL10). This cytokine has been shown to transduce its signal through signal transducer and activator of transcription 3 (STAT3) in keratinocytes. A specific receptor for this cytokine is found to be expressed in skin and upregulated dramatically in psoriatic skin, suggesting a role for this protein in epidermal function and psoriasis.
• Source: E. coli
• Tissue specificity: Expressed at very low levels in skin, trachea, and other tissues.
• Biological activity: Biological activity determined by its ability to activate STAT following receptor ligand interaction.
• Form: Lyophilised:Reconstitute to 1mg/ml using sterile water.
• Storage: The lyophilized protein is stable for a few weeks at room temperature, but best stored at -20°C.
• Sequences of amino acids: MLKTLNLGSC VIATNLQEIR NGFSEIRGSV QAKDGNIDIR ILRRTESLQD TKPANRCCLL RHLLRLYLDR VFKNYQTPDH YTLRKISSLA NSFLTIKKDL RLCHAHMTCH CGEEAMKKYS QILSHFEKLE PQAAVVKALG ELDILLQWME ETE
• Sequence Similarities: Belongs to the IL-10 family.

Gene Information

• Gene Name: IL20 interleukin 20 [ Homo sapiens ]
• Official Symbol: IL20
• Synonyms: IL20; interleukin 20; interleukin-20; IL 20; IL10D; ZCYTO10
• Gene ID: 50604
• mRNA Refseq: NM_018724
• Protein Refseq: NP_061194
• MIM: 605619
• Uniprot ID: Q9NYY1
• Chromosome Location: 1q32
• Pathway: Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Jak-STAT signaling pathway, organism-specific biosystem; Jak-STAT signaling pathway, conserved biosystem
• Function: cytokine activity; interleukin-20 receptor binding; receptor binding