Active Recombinant Human Interleukin 20
Cat.No. : | IL20-500H |
Product Overview : | Recombinant Human IL-20 produced in E.Coli is a homodimeric, non-glycosylated polypeptide chain containing 2 x 153 amino acids and having a total molecular mass of 35,212 Dalton. |
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Cat. No. : | IL20-500H |
Description : | The newly discovered cytokine interleukin-20 (IL-20) is structurally related to IL-10, yet it appears to be an autocrine factor for keratinocytes that regulates their participation in inflammation. |
Species : | Human |
Source : | E.coli |
Form : | Recombinant hIL-20 was lyophilized from a concentrated (1mg/ml) solution containing 100mM sodium chloride and 10mM sodium citrate buffer pH-3. |
Purity : | Purity Greater than 98% as determined by: Analysis by RP-HPLC. Reducing and non-reducing SDS-PAGE. |
Bio-activity : | Human IL-20 is fully biologically active when compared to standard. The Biological Acitivity was determined by the ability to activiate STAT following receptor ligand interaction. |
Physical Appearance : | Sterile Filtered white lyophilized (freeze-dried) powder. |
Solubility : | Centrifuge vial before opening. When reconstituting the product, gently pipet and wash down the sides of the vial to ensure full recovery of the protein into solution. It is recommended to reconstitute the lyophilized product with sterile water at a concentration of 0.1 mg"s/ml, which can be further diluted into other aqueous solutions. |
Purity Greater than 98% as determined by : | Analysis by RP-HPLC. Reducing and non-reducing SDS-PAGE. |
Protein Content determined by : | UV spectroscopy at 280 nm. Analysis by RP-HPLC calibrated against a known standard. Quantitation on SDS-PAGE against a known standard. |
Endotoxin Level : | Endotoxin level as measured by LAL is <0.01ng/ug or <0.1EU/ug. |
Amino acid sequence : | MLKTLNLGSC VIATNLQEIR NGFSEIRGSV QAKDGNIDIR ILRRTESLQD TKPANRCCLL RHLLRLYLDR VFKNYQTPDH YTLRKISSLA NSFLTIKKDL RLCHAHMTCH CGEEAMKKYS QILSHFEKLE PQAAVVKALG ELDILLQWME ETE |
Storage : | Lyophilized product is very stable at -20 degrees. Reconstituted material should be aliquoted and frozen at -20. It is recommended to add a carrier protein (0.1% HSA or BSA) for long term storage. |
Pathways : | Cytokine-cytokine receptor interaction; Jak-STAT signaling pathway |
Tag : | Non |
Gene Name : | IL20 interleukin 20 [ Homo sapiens ] |
Official Symbol : | IL20 |
Synonyms : | IL20; interleukin 20; IL-20; IL10D; ZCYTO10; MGC96907; OTTHUMP00000034618; four alpha helix cytokine; OTTHUMP00000034617; Four alpha helix cytokine Zcyto10 |
Gene ID : | 50604 |
mRNA Refseq : | NM_018724 |
Protein Refseq : | NP_061194 |
MIM : | 605619 |
UniProt ID : | Q9NYY1 |
Chromosome Location : | 1q32 |
Function : | cytokine activity; interleukin-20 receptor binding |
Products Types
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IL20-240H | Active Recombinant Human IL20 Protein (Leu25-Glu176), C-His tagged, Animal-free, Carrier-free | +Inquiry |
IL20-1028H | Recombinant Horse IL20 Protein, His-tagged | +Inquiry |
Il20-173M | Recombinant Active Mouse IL20 Protein, His-tagged(C-ter) | +Inquiry |
Il20-3510M | Recombinant Mouse Il20 Protein, Myc/DDK-tagged | +Inquiry |
◆ Lysates | ||
IL20-5233HCL | Recombinant Human IL20 293 Cell Lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Customer Reviews (3)
Write a reviewThe reliability and reproducibility of the IL20 Protein's performance make it a go-to option for WB experiments.
The IL20 protein is of exceptional quality and will undoubtedly meet my experimental needs with utmost reliability and accuracy.
By utilizing the IL20 protein in my experiments, I can trust that I am working with a product of the highest caliber, backed by a company dedicated to delivering exceptional quality and support.
Q&As (5)
Ask a questionIL-20 has been implicated in tissue repair processes, and harnessing its properties may have implications for regenerative medicine.
IL-20 is being explored as a potential therapeutic target in autoimmune diseases due to its involvement in immune system regulation.
IL-20 is known to promote inflammation, and understanding its mechanisms may lead to targeted anti-inflammatory therapies.
Yes, there are several clinical trials exploring the safety and efficacy of IL-20 inhibitors in various disease contexts.
Tailoring treatments based on individual IL-20 levels and responses is a potential avenue for personalized medicine.
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