IRAK1 Protein

IRAK1

Home / Products / IRAK1

IRAK1

Official Full Name interleukin-1 receptor-associated kinase 1
Background Interleukin-1 (IL-1) receptor-associated kinase (IRAK) is a serine/threonine-specific kinase that can be coprecipitated in an IL-1-inducible manner with the IL-1 receptor. The mammalian family of IRAK molecules contains four members (IRAK1, IRAK2, IRAK3/I
Synonyms IRAK1; interleukin-1 receptor-associated kinase 1; IRAK; pelle; IRAK-1; Pelle homolog;
    • Species :
    • Human
    • Mouse
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • In Vitro Cell Free System
    • Insect Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • MYC/DDK
    • N/A
    • N-GST and C-His
    • No tag
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human IRAK1-1542H Recombinant Human IRAK1, His-tagged E.coli His Inquiry
    Human IRAK1-27500TH Recombinant Human IRAK1 Wheat Germ N/A Inquiry
    Human IRAK1-27502TH Recombinant Human IRAK1 Wheat Germ N/A Inquiry
    Human IRAK1-5436H Recombinant Human Interleukin-1 Receptor-Associated Kinase 1, GST-tagged Insect Cell GST Inquiry
    Human IRAK1-7068H Recombinant Human IRAK1 protein, His-tagged E.coli His Inquiry
    Human IRAK1-5173HCL Recombinant Human IRAK1 293 Cell Lysate HEK293 N/A Inquiry
    Human IRAK1-5174HCL Recombinant Human IRAK1 293 Cell Lysate HEK293 N/A Inquiry
    Human IRAK1-01H Recombinant Human IRAK1 Protein, GST-tagged Insect Cell GST Inquiry
    Human IRAK1-1170H Recombinant Human IRAK1 Protein (R194-S712), Tag Free Insect Cell No tag Inquiry
    Human IRAK1-1171H Recombinant Human IRAK1 Protein (R194-S712), GST tagged Insect Cell GST Inquiry
    Human IRAK1-1200H Recombinant Human IRAK1 Protein, Myc/DDK-tagged HEK293T Myc/DDK Inquiry
    Human IRAK1-257HF Recombinant Full Length Human IRAK1 Protein In Vitro Cell Free System Inquiry
    Human IRAK1-5726HF Recombinant Full Length Human IRAK1 Protein, GST-tagged In Vitro Cell Free System GST Inquiry
    Human IRAK1-799H Recombinant Human IRAK1 Protein, GST/His-tagged E.coli N-GST and C-His Inquiry
    Human IRAK1-2103H Recombinant Human IRAK1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK Inquiry
    Human IRAK1-5056H Recombinant Human IRAK1 Protein, GST-tagged Wheat Germ GST Inquiry
    Human IRAK1-869H Recombinant Human IRAK1 protein, His-tagged Insect cell His Inquiry
    Mouse Irak1-1243M Recombinant Mouse Irak1 Protein, MYC/DDK-tagged HEK293T MYC/DDK Inquiry

    IRAK1 involved in several pathways and played different roles in them. We selected most pathways IRAK1 participated on our site, such as NF-kappa B signaling pathway, Apoptosis, Toll-like receptor signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with IRAK1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    NF-kappa B signaling pathway LCK; NFKBIA; ZAP70; Bcl2a1b; PLCG2; CCL21; PRKCB; BLNK; RELB; IRAK4
    Apoptosis PIK3R5; IRF4A; BIRC3; PRKACBB; NGF; BIRC8; PPP3R1; TICAM1; DIABLO; HMGB2A
    Toll-like receptor signaling pathway PIK3R1; PIK3CD; CXCL9; MAP2K2B; MAPK11; CASP8; Ifna15; MAP3K7; TLR5B; CCL4
    Neurotrophin signaling pathway ABL1; BRAF; CAMK2B; RHOA; PIK3R3; PIK3R5; SH2B2; IRAK1; RAF1; AKT2
    Pertussis Il23a; CALM4; CFL2; ITGB1; RELA; C4A; CASP7; CD14; MAPK10; IRAK1
    Leishmaniasis MAPK1; MARCKSL1; PTPN6; IL12A; FCGR3A; HLA-DOA; STAT1; FCGR3B; FCGR2C; FCGR1A
    Chagas disease (American trypanosomiasis) TGFB3; IL12A; TLR4; IL1B; NFKB1; NOS2; FADD; PPP2R1B; GNA11; AKT2
    Toxoplasmosis STAT1; NOS2; RELA; GNAO1; TNF; LAMB3; MAPK11; AKT1; AKT2; HSPA1L
    Tuberculosis TNFRSF1A; IFNA12; TRADD; ATP6V0C; PPP3R1; MAPK13; HLA-DRB1; HLA-DPB1; CLEC7A; FCGR3A
    Measles CLEC4M; CD3D; IL12B; OAS1A; MYD88; Ifna11; TNFRSF10D; FAS; TLR7; IRF3
    Epstein-Barr virus infection SND1; HLA-F; EIF2AK3; H2-Q10; IKBKB; ENTPD1; NCOR2; IRAK1; CSNK2B; SHFM1

    IRAK1 has several biochemical functions, for example, ATP binding, NF-kappaB-inducing kinase activity, heat shock protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IRAK1 itself. We selected most functions IRAK1 had, and list some proteins which have the same functions with IRAK1. You can find most of the proteins on our site.

    Function Related Protein
    ATP binding PHKG2; CHUK; ATP1A3; ACSF3; SMARCA2; CKMT1B; DAPK2A; PFTK1; DDX53; AK1
    NF-kappaB-inducing kinase activity ALPK2; MAP3K14; PPP4C; RIPK3; IRAK1; IKBKE; ALK
    heat shock protein binding HSPA1A; SSUH2RS1; GRXCR2; GPR37; FAF1; FKBP4; DNAJA2L; APAF1; TFAM; KCNJ11
    interleukin-1 receptor binding IL36A; IL1B; Il1f6; IL1A; IRAK1; IL1RAP; IL37; IL1F10; IL1RN; TRIP6
    kinase activity NADKD1; PDK2B; PRKCHA; NIM1; TRIO; CAMK1DA; RAF1A; PRKAR2AA; cka1; EPHA2A
    protein binding PHC3; DPYSL3; NXT1; REXO1L1; CEP164; C1S; NUSAP1; PDLIM2; PCDH18B; RAB13
    protein heterodimerization activity PKNOX1; MCL1A; ABCG1; KHDRBS2; HIST1H2AM; BOKA; PVALB; KCNH5; ALG2; CXorf15
    protein homodimerization activity CBX1; CARD9; VOX; MCL1; DMRT2A; SPPL2B; BHLHB9; VEGFA; NKX2; Pdgfa&Pdgfb
    protein kinase activity CDK5; PAK2; CAMKV; RNASEL; PRKAG1; TRIM28; TLK1B; MMD2; BMPR1BB; SGK3
    protein serine/threonine kinase activity ACVR1B; IRAK2; TAF1L; TSSK5; STK19; PRKCQ; ACVR2B; ACVR1BA; STK35; PRKACAA
    ubiquitin-protein transferase activity FBXO21; TOPORS; RNF41; TRIM68; MALT1; ZNRF3; MIB2; RNF6; RBCK1; MARCH5L

    IRAK1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IRAK1 here. Most of them are supplied by our site. Hope this information will be useful for your research of IRAK1.

    TRAF6; PELI2; PIN1; MYD88; PELI1

    Zhang, JM; Jia, G; et al. Silencing miR-146a influences B cells and ameliorates experimental autoimmune myasthenia gravis. IMMUNOLOGY 144:56-67(2015).
    Ciccacci, C; Perricone, C; et al. A Multilocus Genetic Study in a Cohort of Italian SLE Patients Confirms the Association with STAT4 Gene and Describes a New Association with HCP5 Gene. PLOS ONE 9:-(2014).

    Q&As (0)

    Ask a Question for All IRAK1 Products

    Required fields are marked with *

    • Verification Code
    ×

    Related Services & Products

    Apply For A Coupon

    $50 OFF Your First Purchase

    Apply For a Coupon

    Enter your email here to subscribe.

    creative biomart inc.

    Easy access to products and services you need from our library via powerful searching tools.

    Follow Us

    Copyright © 2023 Creative BioMart. All Rights Reserved. Terms and Conditions | Privacy Policy