Official Full Name | interleukin-1 receptor-associated kinase 1 |
Background | Interleukin-1 (IL-1) receptor-associated kinase (IRAK) is a serine/threonine-specific kinase that can be coprecipitated in an IL-1-inducible manner with the IL-1 receptor. The mammalian family of IRAK molecules contains four members (IRAK1, IRAK2, IRAK3/I |
Synonyms | IRAK1; interleukin-1 receptor-associated kinase 1; IRAK; pelle; IRAK-1; Pelle homolog; |
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
---|
IRAK1 involved in several pathways and played different roles in them. We selected most pathways IRAK1 participated on our site, such as NF-kappa B signaling pathway, Apoptosis, Toll-like receptor signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with IRAK1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
---|---|
NF-kappa B signaling pathway | LCK; NFKBIA; ZAP70; Bcl2a1b; PLCG2; CCL21; PRKCB; BLNK; RELB; IRAK4 |
Apoptosis | PIK3R5; IRF4A; BIRC3; PRKACBB; NGF; BIRC8; PPP3R1; TICAM1; DIABLO; HMGB2A |
Toll-like receptor signaling pathway | PIK3R1; PIK3CD; CXCL9; MAP2K2B; MAPK11; CASP8; Ifna15; MAP3K7; TLR5B; CCL4 |
Neurotrophin signaling pathway | ABL1; BRAF; CAMK2B; RHOA; PIK3R3; PIK3R5; SH2B2; IRAK1; RAF1; AKT2 |
Pertussis | Il23a; CALM4; CFL2; ITGB1; RELA; C4A; CASP7; CD14; MAPK10; IRAK1 |
Leishmaniasis | MAPK1; MARCKSL1; PTPN6; IL12A; FCGR3A; HLA-DOA; STAT1; FCGR3B; FCGR2C; FCGR1A |
Chagas disease (American trypanosomiasis) | TGFB3; IL12A; TLR4; IL1B; NFKB1; NOS2; FADD; PPP2R1B; GNA11; AKT2 |
Toxoplasmosis | STAT1; NOS2; RELA; GNAO1; TNF; LAMB3; MAPK11; AKT1; AKT2; HSPA1L |
Tuberculosis | TNFRSF1A; IFNA12; TRADD; ATP6V0C; PPP3R1; MAPK13; HLA-DRB1; HLA-DPB1; CLEC7A; FCGR3A |
Measles | CLEC4M; CD3D; IL12B; OAS1A; MYD88; Ifna11; TNFRSF10D; FAS; TLR7; IRF3 |
Epstein-Barr virus infection | SND1; HLA-F; EIF2AK3; H2-Q10; IKBKB; ENTPD1; NCOR2; IRAK1; CSNK2B; SHFM1 |
IRAK1 has several biochemical functions, for example, ATP binding, NF-kappaB-inducing kinase activity, heat shock protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IRAK1 itself. We selected most functions IRAK1 had, and list some proteins which have the same functions with IRAK1. You can find most of the proteins on our site.
Function | Related Protein |
---|---|
ATP binding | PHKG2; CHUK; ATP1A3; ACSF3; SMARCA2; CKMT1B; DAPK2A; PFTK1; DDX53; AK1 |
NF-kappaB-inducing kinase activity | ALPK2; MAP3K14; PPP4C; RIPK3; IRAK1; IKBKE; ALK |
heat shock protein binding | HSPA1A; SSUH2RS1; GRXCR2; GPR37; FAF1; FKBP4; DNAJA2L; APAF1; TFAM; KCNJ11 |
interleukin-1 receptor binding | IL36A; IL1B; Il1f6; IL1A; IRAK1; IL1RAP; IL37; IL1F10; IL1RN; TRIP6 |
kinase activity | NADKD1; PDK2B; PRKCHA; NIM1; TRIO; CAMK1DA; RAF1A; PRKAR2AA; cka1; EPHA2A |
protein binding | PHC3; DPYSL3; NXT1; REXO1L1; CEP164; C1S; NUSAP1; PDLIM2; PCDH18B; RAB13 |
protein heterodimerization activity | PKNOX1; MCL1A; ABCG1; KHDRBS2; HIST1H2AM; BOKA; PVALB; KCNH5; ALG2; CXorf15 |
protein homodimerization activity | CBX1; CARD9; VOX; MCL1; DMRT2A; SPPL2B; BHLHB9; VEGFA; NKX2; Pdgfa&Pdgfb |
protein kinase activity | CDK5; PAK2; CAMKV; RNASEL; PRKAG1; TRIM28; TLK1B; MMD2; BMPR1BB; SGK3 |
protein serine/threonine kinase activity | ACVR1B; IRAK2; TAF1L; TSSK5; STK19; PRKCQ; ACVR2B; ACVR1BA; STK35; PRKACAA |
ubiquitin-protein transferase activity | FBXO21; TOPORS; RNF41; TRIM68; MALT1; ZNRF3; MIB2; RNF6; RBCK1; MARCH5L |
IRAK1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IRAK1 here. Most of them are supplied by our site. Hope this information will be useful for your research of IRAK1.
TRAF6; PELI2; PIN1; MYD88; PELI1
Easy access to products and services you need from our library via powerful searching tools.
Copyright © 2023 Creative BioMart. All Rights Reserved. Terms and Conditions | Privacy Policy