Recombinant Human IRAK1 protein, His-tagged

Cat.No. : IRAK1-7068H
Product Overview : Recombinant Human IRAK1 aa. (Phe212~Glu440 (Accession # P51617)) fused with N-terminal His tag was produced in E. coli cells.
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Source : E. coli
Species : Human
Tag : His
Form : Freeze-dried powder
Molecular Mass : Predicted Molecular Mass: 27.1kDa
Protein length : Phe212~Glu440 (Accession # P51617)
Endotoxin : <1.0EU per 1ug (determined by the LAL method)
Purity : >95%
Characteristic : The isoelectric point is 7.2.
Applications : SDS-PAGE; WB; ELISA; IP.
Stability : The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
Storage buffer : Supplied as lyophilized form in PBS, pH7.4, containing 5% sucrose, 0.01% sarcosyl.
Reconstitution : Reconstitute in sterile PBS, pH7.2-pH7.4.
Gene Name : IRAK1 interleukin 1 receptor associated kinase 1 [ Homo sapiens (human) ]
Official Symbol : IRAK1
Synonyms : IRAK1; interleukin 1 receptor associated kinase 1; IRAK; pelle; interleukin-1 receptor-associated kinase 1; IRAK-1; Pelle homolog
Gene ID : 3654
mRNA Refseq : NM_001025242.1
Protein Refseq : NP_001020413.1
UniProt ID : P51617

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Customer Reviews (3)

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Reviews
04/01/2021

    The IRAK1 protein stands out for its exceptional quality, making it an excellent choice to meet my experimental requirements.

    04/21/2020

      The IRAK1 protein's compatibility with various experimental techniques adds to its versatility.

      05/12/2017

        Its stability and compatibility make it an excellent tool for visualizing and characterizing protein structures at high resolution.

        Q&As (5)

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        Are there any ongoing clinical trials targeting IRAK1 for cancer treatment? 03/16/2023

        Yes, there are several clinical trials exploring the inhibition of IRAK1 as a therapeutic strategy for various types of cancer.

        How is IRAK1 protein implicated in autoimmune diseases? 06/19/2020

        IRAK1 is involved in the signaling pathways that can lead to the development of autoimmune diseases by regulating the immune system's response to self-antigens.

        How does the expression of IRAK1 relate to inflammatory diseases? 01/08/2020

        Elevated levels of IRAK1 expression have been observed in inflammatory diseases, suggesting its involvement in the dysregulation of inflammatory responses.

        In what ways can IRAK1 be a target for drug development in inflammatory conditions? 08/23/2016

        Inhibiting IRAK1 activity is being investigated as a potential therapeutic approach for managing inflammatory conditions, offering a target for drug development.

        What clinical significance does IRAK1 hold in cancer research? 03/31/2016

        IRAK1 has been identified as a potential target for cancer therapy, as it plays a role in promoting tumor growth and evasion of the immune system.

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