Active Recombinant Human IRAK1 Protein, GST-tagged

• Cat.No.: IRAK1-01H
• Product Overview: Recombinant full-length human IRAK1 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.

Specification

• Species: Human
• Source: Insect Cells
• Tag: GST
• Description: This gene encodes the interleukin-1 receptor-associated kinase 1, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. This gene is partially responsible for IL1-induced upregulation of the transcription factor NF-kappa B. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
• Bio-activity: The specific activity of IRAK1 was determined to be 31 nmol/min/mg
• Molecular Mass: 132 kDa
• Purity: > 90%
• Stability: One year at -70 centigrade from date of shipment.
• Storage: Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
• Concentration: 0.1 μg/μL
• Storage Buffer: 20 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1mM PMSF, and 25% glycerol.
• Shipping: Dry ice.

Gene Information

• Gene Name: IRAK1 interleukin 1 receptor associated kinase 1 [ Homo sapiens (human) ]
• Official Symbol: IRAK1
• Synonyms: IRAK1; interleukin 1 receptor associated kinase 1; IRAK; pelle; interleukin-1 receptor-associated kinase 1; IRAK-1; Pelle homolog; EC 2.7.11.1
• Gene ID: 3654
• mRNA Refseq: NM_001569
• Protein Refseq: NP_001560
• MIM: 300283
• UniProt ID: P51617