Recombinant Full Length Human IRAK1 Protein, GST-tagged

• Cat.No.: IRAK1-5726HF
• Product Overview: Human IRAK1 full-length ORF ( AAH14963.1, 1 a.a. - 633 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes the interleukin-1 receptor-associated kinase 1, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. This gene is partially responsible for IL1-induced upregulation of the transcription factor NF-kappa B. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 94.4 kDa
• Protein Length: 633 amino acids
• AA Sequence: MAGGPGPGEPAAPGAQHFLYEVPPW VMCRFYKVMDALEPADWCQFAALIV RDQTELRLCERSGQRTASVLWPWIN RNARVADLVHILTHLQLLRARDIIT AWHPPAPLPSPGTTAPRPSSIPAPA EAEAWSPRKLPSSASTFLSPAFPGS QTHSGPELGLVPSPASLWPPPPSPA PSSTKPGPESSVSLLQGARPSPFCW PLCEISRGTHNFSEELKIGEGGFGC VYRAVMRNTVYAVKRLKENADLEWT AVKQSFLTEVEQLSRFRHPNIVDFA GYCAQNGFYCLVYGFLPNGSLEDRL HCQTQACPPLSWPQRLDILLGTARA IQFLHQDSPSLIHGDIKSSNVLLDE RLTPKLGDFGLARFSRFAGSSPSQS SMVARTQTVRGTLAYLPEEYIKTGR LAVDTDTFSFGVVVLETLAGQRAVK THGARTKYLVYERLEKLQAVVAGVP GHLEAASCIPPSPQENSYVSSTGRA HSGAAPWQPLAAPSGASAQAAEQLQ RGPNQPVESDESLGGLSAALRSWHL TPSCPLDPAPLREAGCPQGDTAGES SWGSGPGSRPTAVEGLALGSSASSS SEPPQIIINPARQKMVQKLALYEDG ALDSLQLLSSSSLPGLGLEQDRQGP EESDEFQS
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: IRAK1 interleukin-1 receptor-associated kinase 1 [ Homo sapiens ]
• Official Symbol: IRAK1
• Synonyms: IRAK1; interleukin-1 receptor-associated kinase 1; IRAK; pelle; IRAK-1; Pelle homolog
• Gene ID: 3654
• mRNA Refseq: NM_001025242
• Protein Refseq: NP_001020413
• MIM: 300283
• UniProt ID: P51617