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Official Full Name integrin, alpha 8
Background Integrin alpha-8 is a protein that in humans is encoded by the ITGA8 gene.
Synonyms ITGA8; integrin, alpha 8; integrin alpha-8; Integrin alpha 8; ITGA 8; OTTHUMP00000019207
    • Species :
    • Chicken
    • Human
    • Mouse
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Human Cell
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • C-Myc/DDK
    • Flag
    • His
    • GST
    • Myc/DDK
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ITGA8 & ITGB1-1876HCL Recombinant Human ITGA8 & ITGB1 cell lysate Human Cell N/A
    Human ITGA8-246H Recombinant Human ITGA8 Protein, His/GST-tagged E.coli His/GST
    Human ITGA8-2613H Recombinant Human ITGA8 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human ITGA8-287H Recombinant Human ITGA8 Protein, MYC/DDK-tagged, C13 and N15-labeled HEK293 C-Myc/DDK
    Human ITGA8-4118H Recombinant Human ITGA8, flag & His tagged Human Cell Flag/His
    Human ITGA8-4993H Recombinant Human ITGA8 Protein, GST-tagged Wheat Germ GST
    Mouse Itga8-3598M Recombinant Mouse Itga8 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Mouse ITGA8-8354M Recombinant Mouse ITGA8 Protein Mammalian Cell His
    Chicken ITGA8-6840C Recombinant Chicken ITGA8 Mammalian Cell His
    Zebrafish ITGA8-6497Z Recombinant Zebrafish ITGA8 Mammalian Cell His

    ITGA8 involved in several pathways and played different roles in them. We selected most pathways ITGA8 participated on our site, such as PIK-Akt signaling pathway, Focal adhesion, ECM-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with ITGA8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    PIK-Akt signaling pathway ATF4; RPS6; TLR2; FGF17; SYK; ITGB1; ITGA2; ITGA1; IFNA13; GNG10
    Focal adhesion IGF1; THBS3; TNC; ITGA3B; PARVB; RAC1A; PDGFD; IGF1R; COL5A2; RAC3
    ECM-receptor interaction LAMA4; SDC1; FN1A; ITGB8; COL2A1A; COL4A3; THBS4; ITGB6; SDC4; ITGB1A
    Cell adhesion molecules (CAMs) NRXN3A; CADM1; CD276; NEO1; ITGB7; BMA1; NCAM2; CLDN5B; CLDN5A; CDH4
    Regulation of actin cytoskeleton ACTN3; VIL1; MYL2B; PIP5K1C; ABI2; ITGB8; MYL10; RHOAB; DIAPH1; ACTN4
    Hypertrophic cardiomyopathy (HCM) SGCG; TPM2; ITGB6; TNNI3; PRKAG2; PRKAB1; TNNC1; TGFB1; CACNG4; MYBPC3
    Arrhythmogenic right ventricular cardiomyopathy (ARVC) SLC8A1; CTNNA3; DSG2; PKP2; ITGA10; CTNNA2; SGCB; DSP; ACTB; AASS
    Dilated cardiomyopathy ITGA4; TPM3; CACNA2D1; CACNG7; CACNA2D2; CACNB3; ITGB7; ITGA2; TGFB1; LMNA

    ITGA8 has several biochemical functions, for example, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ITGA8 itself. We selected most functions ITGA8 had, and list some proteins which have the same functions with ITGA8. You can find most of the proteins on our site.

    Function Related Protein
    metal ion binding HBB-B2; ATF7A; ZFP346; FBXO30B; LHX1A; RXRBA; NRXN3A; C1GALT1B; CYB5A; CXXC1B

    ITGA8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ITGA8 here. Most of them are supplied by our site. Hope this information will be useful for your research of ITGA8.

    Bakdash, G; Vogelpoel, LTC; et al. Retinoic acid primes human dendritic cells to induce gut-homing, IL-10-producing regulatory T cells. MUCOSAL IMMUNOLOGY 8:265-278(2015).
    Shi, L; Zhang, LC; et al. Expression, purification and renaturation of truncated human integrin beta 1 from inclusion bodies of Escherichia coli. PROTEIN EXPRESSION AND PURIFICATION 107:13-19(2015).

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