|Official Full Name||integrin, alpha 8|
|Background||Integrin alpha-8 is a protein that in humans is encoded by the ITGA8 gene.|
|Synonyms||ITGA8; integrin, alpha 8; integrin alpha-8; Integrin alpha 8; ITGA 8; OTTHUMP00000019207|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
ITGA8 involved in several pathways and played different roles in them. We selected most pathways ITGA8 participated on our site, such as PIK-Akt signaling pathway, Focal adhesion, ECM-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with ITGA8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|PIK-Akt signaling pathway||ATF4; RPS6; TLR2; FGF17; SYK; ITGB1; ITGA2; ITGA1; IFNA13; GNG10|
|Focal adhesion||IGF1; THBS3; TNC; ITGA3B; PARVB; RAC1A; PDGFD; IGF1R; COL5A2; RAC3|
|ECM-receptor interaction||LAMA4; SDC1; FN1A; ITGB8; COL2A1A; COL4A3; THBS4; ITGB6; SDC4; ITGB1A|
|Cell adhesion molecules (CAMs)||NRXN3A; CADM1; CD276; NEO1; ITGB7; BMA1; NCAM2; CLDN5B; CLDN5A; CDH4|
|Regulation of actin cytoskeleton||ACTN3; VIL1; MYL2B; PIP5K1C; ABI2; ITGB8; MYL10; RHOAB; DIAPH1; ACTN4|
|Hypertrophic cardiomyopathy (HCM)||SGCG; TPM2; ITGB6; TNNI3; PRKAG2; PRKAB1; TNNC1; TGFB1; CACNG4; MYBPC3|
|Arrhythmogenic right ventricular cardiomyopathy (ARVC)||SLC8A1; CTNNA3; DSG2; PKP2; ITGA10; CTNNA2; SGCB; DSP; ACTB; AASS|
|Dilated cardiomyopathy||ITGA4; TPM3; CACNA2D1; CACNG7; CACNA2D2; CACNB3; ITGB7; ITGA2; TGFB1; LMNA|
ITGA8 has several biochemical functions, for example, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ITGA8 itself. We selected most functions ITGA8 had, and list some proteins which have the same functions with ITGA8. You can find most of the proteins on our site.
|metal ion binding||HBB-B2; ATF7A; ZFP346; FBXO30B; LHX1A; RXRBA; NRXN3A; C1GALT1B; CYB5A; CXXC1B|
ITGA8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ITGA8 here. Most of them are supplied by our site. Hope this information will be useful for your research of ITGA8.