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Official Full Name integrin, alpha 9
Background This gene encodes an alpha integrin. Integrins are heterodimeric integral membrane glycoproteins composed of an alpha chain and a beta chain that mediate cell-cell and cell-matrix adhesion. The protein encoded by this gene, when bound to the beta 1 chain, forms an integrin that is a receptor for VCAM1, cytotactin and osteopontin. Expression of this gene has been found to be upregulated in small cell lung cancers. [provided by RefSeq, Jul 2008]
Synonyms ITGA9; integrin, alpha 9; RLC; ITGA4L; ALPHA-RLC; integrin alpha-9; integrin alpha-RLC;
    • Species :
    • Chicken
    • Human
    • Mouse
    • Source :
    • CHO
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • MYC/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ITGA9-1236H Recombinant Human ITGA9 protein, GST-tagged E.coli GST
    Human ITGA9-176H Recombinant Human ITGA9, His-tagged E.coli His
    Human ITGA9-2053H Recombinant Human ITGA9 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human ITGA9-247H Recombinant Human ITGA9 Protein, His/GST-tagged E.coli His/GST
    Human ITGA9-4992H Recombinant Human ITGA9 Protein, GST-tagged Wheat Germ GST
    Human ITGA9-5130HCL Recombinant Human ITGA9 293 Cell Lysate HEK293 N/A
    Mouse Itga9&Itgb1-516M Recombinant Mouse Itga9&Itgb1 CHO N/A
    Mouse Itga9-248M Recombinant Mouse Itga9 Protein, His/GST-tagged E.coli His/GST
    Mouse Itga9-251M Recombinant Mouse Itga9 Protein, MYC/DDK-tagged HEK293T MYC/DDK
    Chicken ITGA9-2077C Recombinant Chicken ITGA9 Mammalian Cell His

    ITGA9 involved in several pathways and played different roles in them. We selected most pathways ITGA9 participated on our site, such as PIK-Akt signaling pathway, Focal adhesion, ECM-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with ITGA9 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    PIK-Akt signaling pathway IL6; ANGPT4; TP53; ITGB3; PPP2R1A; BCL2; VWF; PDGFB; PCK2; FGF11
    Focal adhesion PXN; PARVB; ITGB3B; CCND2A; FYNB; PDGFD; DIAPH1; COL4A1; FN1; ITGA4
    ECM-receptor interaction ITGA9; SDC1; ITGB5; COL1A1A; COL1A1; ITGA6B; ITGA3B; THBS3; LAMC3; ITGB1
    Cell adhesion molecules (CAMs) NCAM2; Ntng2; CD4; BMA1; HLA-DQA2; JAM2; CNTN2; CD40; PVRL3; ESAM
    Regulation of actin cytoskeleton PAK3; VAV3B; ITGA7; Pdgfa&Pdgfb; FGFR1A; FGF13B; FGF16; FGF18A; PFN3; GIT1
    Hypertrophic cardiomyopathy (HCM) CACNB1; ITGB8; CACNG1; ITGA2; CACNG7; ITGA9; SLC8A1; ACTB; SGCD; TNF
    Arrhythmogenic right ventricular cardiomyopathy (ARVC) DMD; LAMA2; GJA1; ITGB5; DSG2; CACNB1; CDH2; CACNA2D2; CACNA2D3; ITGA8
    Dilated cardiomyopathy EMD; ITGB3; SLC8A1; PRKACA; ITGB4; CACNB4; CACNG8; TNNI3; ITGA9; SGCB

    ITGA9 has several biochemical functions, for example, collagen binding, laminin binding, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ITGA9 itself. We selected most functions ITGA9 had, and list some proteins which have the same functions with ITGA9. You can find most of the proteins on our site.

    Function Related Protein
    collagen binding LRRC15; ITGA10; DDR1; SMAD7; Pdgfa&Pdgfb; PCOLCE; FN1; NID1; MRC2; LACRT
    laminin binding ITGB1; NCL; LYPD5; NID1; ACHE; LYPD3; AGRN; ITGA7; GPC1; RPSA
    metal ion binding MPPED2; ZNF692; COL27A1; EGLN1B; CD209; SAR1B; SMAD2; TRIM35-27; SALL3; FKBP8

    ITGA9 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ITGA9 here. Most of them are supplied by our site. Hope this information will be useful for your research of ITGA9.

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