ITIH4
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Official Full Name
inter-alpha-trypsin inhibitor heavy chain family, member 4 -
Overview
The protein encoded by this gene is secreted into the blood, where it is cleaved by plasma kallikrein into two smaller forms. Expression of this gene has been detected only in liver, and it seems to be upregulated during surgical trauma. This gene is part of a cluster of similar genes on chromosome 3. Two transcript variants encoding different isoforms have been found for this gene. -
Synonyms
ITIH4;inter-alpha-trypsin inhibitor heavy chain family, member 4;inter alpha (globulin) inhibitor H4 (plasma Kallikrein sensitive glycoprotein) , ITIHL1;inter-alpha-trypsin inhibitor heavy chain H4;H4P;IHRP;plasma Kallikrein sensitive glycoprotein
Recombinant Proteins
- Human
- Mouse
- Rat
- CHO
- Mammalian Cells
- HEK293
- E.coli
- Yeast
- His
- Flag
- Avi
- Fc
- T7
- GST
- DDK
- Myc
- SUMO
Involved Pathway
ITIH4 involved in several pathways and played different roles in them. We selected most pathways ITIH4 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ITIH4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
ITIH4 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by ITIH4 itself. We selected most functions ITIH4 had, and list some proteins which have the same functions with ITIH4. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Interacting Protein
ITIH4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ITIH4 here. Most of them are supplied by our site. Hope this information will be useful for your research of ITIH4.
Resources
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References
- Webber, J; Stone, TC; et al. Proteomics Analysis of Cancer Exosomes Using a Novel Modified Aptamer-based Array (SOMAscan(TM)) Platform*. MOLECULAR & CELLULAR PROTEOMICS 13:1050-1064(2014).
- Pineiro, M; Lampreave, F; et al. Development and validation of an ELISA for the quantification of pig Major Acute phase Protein (Pig-MAP). VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY 127:228-234(2009).
