JAG2
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Official Full Name
jagged 2
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Overview
The Notch signaling pathway is an intercellular signaling mechanism that is essential for proper embryonic development. Members of the Notch gene family encode transmembrane receptors that are critical for various cell fate decisions. The protein encoded by this gene is one of several ligands that activate Notch and related receptors. Two transcript variants encoding different isoforms have been found for this gene. -
Synonyms
JAG2; jagged 2; protein jagged-2; HJ2; SER2;
- Recombinant Proteins
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- CHO
- E.coli
- HEK293
- Mammalian Cell
- Mammalian cells
- Wheat Germ
- Fc
- His
- Avi
- GST
- T7
- Non
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
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Human | JAG2-229H | Active Recombinant Human JAG2, Fc Chimera | CHO | Fc |
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Human | JAG2-29877TH | Recombinant Human JAG2 | Wheat Germ | Non | 90 amino acids |
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Human | JAG2-382H | Recombinant Human JAG2, Fc-tagged | HEK293 | Fc | 1-1054 |
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Human | JAG2-601H | Recombinant Human JAG2 | Mammalian Cell | His |
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Human | JAG2-3182H | Recombinant Human JAG2 Protein, His (Fc)-Avi-tagged | HEK293 | His&Fc&Avi |
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Human | JAG2-1869H | Recombinant Human JAG2 protein, His-tagged | E.coli | His | Phe714~His981 |
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Human | JAG2-3397H | Recombinant Human JAG2 protein, His-GST-tagged | E.coli | His&GST | Phe714~His981 |
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Human | JAG2-3182H-B | Recombinant Human JAG2 Protein Pre-coupled Magnetic Beads | HEK293 |
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Mouse | Jag2-5666M | Active Recombinant Mouse Jagged 2, Fc-tagged | Mammalian cells | Fc | Met27-Lys1084 |
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Mouse | Jag2-383M | Recombinant Mouse Jag2, Fc-tagged | HEK293 | Fc | 24-1082 |
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Mouse | JAG2-8407M | Recombinant Mouse JAG2 Protein | Mammalian Cell | His |
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Mouse | Jag2-79M | Recombinant Mouse Jag2 Protein, His (Fc)-Avi-tagged | HEK293 | His&Fc&Avi |
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Mouse | Jag2-79M-B | Recombinant Mouse Jag2 Protein Pre-coupled Magnetic Beads | HEK293 |
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Mouse | Jag2-1870M | Recombinant Mouse Jag2 protein, His & T7-tagged | E.coli | His&T7 | Cys709~Pro941 |
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- Involved Pathway
- Protein Function
- Interacting Protein
- Other Resource
JAG2 involved in several pathways and played different roles in them. We selected most pathways JAG2 participated on our site, such as Activated NOTCH1 Transmits Signal to the Nucleus, Constitutive Signaling by NOTCH1 HD Domain Mutants, Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants, which may be useful for your reference. Also, other proteins which involved in the same pathway with JAG2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Activated NOTCH1 Transmits Signal to the Nucleus | JAG1;DTX2;JAG2;DNER;DLK1;MIB1;CNTN1;ADAM10 |
Constitutive Signaling by NOTCH1 HD Domain Mutants | MIB1;JAG1;JAG2;ADAM10 |
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants | HDAC6;HEY2;MIB1;HEY1;JAG2;ADAM10;HEYL;HDAC5;CDK8 |
Constitutive Signaling by NOTCH1 PEST Domain Mutants | HDAC6;JAG2;HEY1;ADAM10;HEY2;JAG1;CCNC;HDAC5;MIB1 |
Constitutive Signaling by NOTCH1 t(7 | JAG1;JAG2 |
9)(NOTCH1:M1580_K2555) Translocation Mutant | JAG1;JAG2 |
Delta-Notch Signaling Pathway | HIVEP3;ASCL1;SMAD3B;ZFPM1;MAGEA1;CNTN1B;TLE1;ADAM10A;CNTN1 |
Disease | EEF2;FKBP1A;PRELP;GPC5;OPN1MW;AP1G1;PACS1;STRA6;FMOD |
Diseases of signal transduction | KREMEN1;TRIM24;OPN1MW2;MIB1;HEYL;CUX1;CDK8;STRA6;FGFR1OP |
JAG2 has several biochemical functions, for example, Notch binding, calcium ion binding, growth factor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by JAG2 itself. We selected most functions JAG2 had, and list some proteins which have the same functions with JAG2. You can find most of the proteins on our site.
Function | Related Protein |
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Notch binding | EGFL7;JAG1A;JAG2B;DTX1;JAG1B;ADAM17;JAG2;DLL1;SNW1 |
calcium ion binding | S100A11;MAN1A;GUCA1D;ENPP1;PCDHB15;ANXA7;CPNE6;S100A8;ATP2A1 |
growth factor activity | PDGFA;NRG3;CECR1;TGFA;PDGFAB;VEGFAB;NRTN;OSGIN1;CSF3 |
protein binding | ARF4;GRIN2A;AOC3;ADAM22;CAPZA1;MTA2;NOLC1;CCNA1;IFIT2 |
JAG2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with JAG2 here. Most of them are supplied by our site. Hope this information will be useful for your research of JAG2.
GFI1B; CACNA1A; ATXN7; ATN1; thrS2; q81wx2_bacan; q9wmx2-pro_0000037548
Research Area
- Reviews
- Q&As
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