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Official Full Name keratin 27
Background This gene encodes a member of the type I (acidic) keratin family, which belongs to the superfamily of intermediate filament (IF) proteins. Keratins are heteropolymeric structural proteins which form the intermediate filament. These filaments, along with actin microfilaments and microtubules, compose the cytoskeleton of epithelial cells. The type I keratin genes are clustered in a region of chromosome 17q12-q21.
Synonyms KRT27; keratin 27; KRT25C; keratin, type I cytoskeletal 27 K27; K25C; CK-27; keratin-27; keratin 25C; keratin-25C; cytokeratin-27; type I inner root sheath specific keratin 25 irs3; type I inner root sheath-specific keratin-K25irs3; OTTHUMP00000164526; keratin K27; K25irs3 KRT27; K25irs3
    • Species :
    • Human
    • Mouse
    • Rat
    • Source :
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human KRT27-4858H Recombinant Human KRT27 Protein, GST-tagged Wheat Germ GST
    Mouse KRT27-8830M Recombinant Mouse KRT27 Protein Mammalian Cell His
    Rat KRT27-3321R Recombinant Rat KRT27 Protein Mammalian Cell His

    KRT27 involved in several pathways and played different roles in them. We selected most pathways KRT27 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with KRT27 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    KRT27 has several biochemical functions, for example, structural molecule activity. Some of the functions are cooperated with other proteins, some of the functions could acted by KRT27 itself. We selected most functions KRT27 had, and list some proteins which have the same functions with KRT27. You can find most of the proteins on our site.

    Function Related Protein
    structural molecule activity JAG1; MAP2; KRT23; CYT1L; LCE3E; KRT80; KRT77; COPG2; IFLTD1; SNTB2

    KRT27 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KRT27 here. Most of them are supplied by our site. Hope this information will be useful for your research of KRT27.


    Tanaka, S; Miura, I; et al. Mutations in the helix termination motif of mouse type IIRS keratin genes impair the assembly of keratin intermediate filament. GENOMICS 90:703-711(2007).

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